Gene Information

Name : PARA_12090 (PARA_12090)
Accession : YP_004822901.1
Strain : Haemophilus parainfluenzae T3T1
Genome accession: NC_015964
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 1200649 - 1202694 bp
Length : 2046 bp
Strand : -
Note : -

DNA sequence :
ATGAAACTTTTCTTATGTGAAAAACCATCACAAGGTAATGATATTGCAAAAATATTAGGCGCGACAAAGCGTGGTGAAGG
TTGTTTATCAACACCTGATGGTCAGCTTACAGTTACCTGGGGAATTGGTCATCTAGTAGAGCAATTTAATCCTGAAGAAT
ATGATCCTGCCTTTAAAAAGTGGGCTTTTGAGACCTTGCCAATTATCCCGGGTAAATGGGGGCTTTCACCTAAAAAAGAA
ACAAAAAAACAGTTCAACGTCGTAATGAAACTTATCAAACAAGCTAAACTTGTTGTCATTGCAACCGATATTGATAGAGA
GGGCGAAACTATAGCAAGAGAATTGCTGGATTTAGCAGGATTTCGAGGGCAAATAAAACGCCTTTGGTTGTCTGCACTAG
ATGATGCCAGTATTCGTAAAGCCTTGGGTGCGCTTAAAGATAATGAGGAGACTCTCCCTCTTTACTATGCAGGACTTGCA
CGTAGTCGAGCAGATTGGCTTATTGGTATGAATTTCTCTCGTATCTATACCTTATTAGCGCAACAACAAGGGTATCAAGG
GAAACCTTTAAGTGTTGGGCGGGTACAAACTCCAACATTAAGCCTGGTTGTTAATCGTGACCGTGAGATAAAAAACTTCA
TTCCTAAGCAACATTTTGCTTTGCAAGTAATGCTTTCTGATGGAAATCAGCATTTTGCTACGCAATATGTTATTCCGGAG
CAATATTGTGATCCTGATGGACTTTGTTTGTCTGCCCAAGTTATACAAGCAGCAAATCAGCAAATTCGTCAATTGGGCCA
AGCGAAAATGGAATCAGTTGAAACTAAACGTGAAAGACAAAATGCTCCACTTTGCTTTGCATTAAGTGACTTACAATCAG
AAGCTAACCGCCTTTATGGACTGGGTGCGCAAAGGGTATTGGATATAGCTCAATCACTCTATGAGACTCACAAAGCGACA
ACCTATCCTAGAACAGATTGTGGTTATTTACCGGAGTCTCAGTTTGCTGAAGCCCCTAAAATTATCCAATGTTTATTGCA
ATCCGATAATCGATTACAACCCCTTGCAGGTATGTTAAACCTTAATCAAAAATCACGAGTTTGGAATGATAAAAAAATTA
CTGCTCACCATGGCATTATTCCGACTATGATTAAAGCTGATATTAGCAAAATGTCTGATGAAGAATTAAAGCTCTATGAT
CTCATACGTCGTCGTTATTTAGCTCAATTCTTACCTGTTTCTGAAACAGATAAGACACAAATTATTTTGAAGTGCGGTCA
ACATATATTAAGTGCACGTGGGAATGTGCTTATTGCTCCAGGTTGGAAAATTCTATTTGGCAAATCACTTGATGAAGATG
ATGATGCACCTCAAGCCTTGCCGACGTTAAAGCAAGGACAAATCTGTCAGATTTCTGATTCAGAAATAAAAACCTTACAA
ACATCACCACCTAATCACTTCACGGAAGGCACATTGCTCACCGCAATGAAAAATGCAGCTCGCTTTGTAACTGATGAGCG
TTTAAAACAACGCTTACGAGAAACTGAAGGGCTTGGTACAGAAGCCACCCGGGCGGGAACGATTCAAGGTTTGATTGATA
AAGGTTTCTTGAAAAAGAAAGGTAAATCACTATTAGCGACAGATGAAGCAATGACGCTAATTGATAATTTACCTCAGATG
TTAAAAGATCCTGGTTTAACCGCACTTTGGGAGCAAGCGCTCAATCAAATTGCTGAAAGAACGCTTTCGCTAGAAGTGTT
TATGCAAAAACAAGAAGTCTTTGTGCGGCATTTGATGGCTGATTGCCTTAAAAAGGGAATGAGTTTGGGGAATATTGAAA
TTCGTAAATGCCCTAAGTGCGGTGCACCAATGATTAAAAGAAATGGTAAAAATGGGGCTTTTTTGGGGTGTTCTGCTTAT
CCAAATTGCCAACATATTGAAAATTTTGATAGCAAAAAGAATACTAAGGGCGCGAAAAGTTCTAAGAAAACATCGAGTAA
AAGTGTTAGCGAGCAAATTTCATCTTTACGAAGCTTATTGAATTAG

Protein sequence :
MKLFLCEKPSQGNDIAKILGATKRGEGCLSTPDGQLTVTWGIGHLVEQFNPEEYDPAFKKWAFETLPIIPGKWGLSPKKE
TKKQFNVVMKLIKQAKLVVIATDIDREGETIARELLDLAGFRGQIKRLWLSALDDASIRKALGALKDNEETLPLYYAGLA
RSRADWLIGMNFSRIYTLLAQQQGYQGKPLSVGRVQTPTLSLVVNRDREIKNFIPKQHFALQVMLSDGNQHFATQYVIPE
QYCDPDGLCLSAQVIQAANQQIRQLGQAKMESVETKRERQNAPLCFALSDLQSEANRLYGLGAQRVLDIAQSLYETHKAT
TYPRTDCGYLPESQFAEAPKIIQCLLQSDNRLQPLAGMLNLNQKSRVWNDKKITAHHGIIPTMIKADISKMSDEELKLYD
LIRRRYLAQFLPVSETDKTQIILKCGQHILSARGNVLIAPGWKILFGKSLDEDDDAPQALPTLKQGQICQISDSEIKTLQ
TSPPNHFTEGTLLTAMKNAARFVTDERLKQRLRETEGLGTEATRAGTIQGLIDKGFLKKKGKSLLATDEAMTLIDNLPQM
LKDPGLTALWEQALNQIAERTLSLEVFMQKQEVFVRHLMADCLKKGMSLGNIEIRKCPKCGAPMIKRNGKNGAFLGCSAY
PNCQHIENFDSKKNTKGAKSSKKTSSKSVSEQISSLRSLLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 0.0 68
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 9e-162 52
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 1e-157 52
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 3e-153 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 4e-153 51
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 4e-153 51
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 3e-151 50
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 5e-143 47