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Name : Entas_4593 (Entas_4593) Accession : YP_004821650.1 Strain : Genome accession: NC_015963 Putative virulence/resistance : Unknown Product : integrase catalytic subunit Function : - COG functional category : L : Replication, recombination and repair COG ID : COG2801 EC number : - Position : 100576 - 101415 bp Length : 840 bp Strand : - Note : KEGG: enc:ECL_A128 putative IS911 transposase orfA; manually curated; PFAM: Integrase, catalytic core DNA sequence : GTGGTTACTCTCTGCCACGTGTTCGGGGTTCATCGCAGTAGCTACAAATACTGGAAAAACCGTCCTGAAAAGCCAGACGG CAAACGGGCTGTATTACGCAGCCAGGTACTTGAGCTACATGGCATCAGCCACGGTTCTGCCGGAGCAAGAAGCATCGCCA CAATGGCCACTCAGAGAGGCTACCAGATGGGGCGCTGGCTCGCTGGCAGACTCATGAAAGAGCTGAGGCTGGTCAGTTGC CAGCAGCCGACTCACCGGTACAGGCGTGGCGGTCATGAGCACGTTGCTATCCCGAATCATCTTGAGCGACAGTTCGCCGT AACAGAGCCAAACCAGGTGTGGTGCGGTGATGTGACCTATATCTGGACAGGTAAGCGCTGGGCGTACCTTGCTGTTGTTC TCGACCTGTTCGCAAGGAAACCAGTAGGCTGGGCAATGTCGTTCTCACCGGACAGCAGACTCACTATGAAAGCGCTGGAA ATGGCATGGGAAACGCGCGGCAAGCCCGTTGGAGTAATGTTCCACAGCGATCAAGGTAGTCATTATACGAGCAGGCAGTT CCGGCAGTTACTGTGGCGATACCGGATCAGACAGAGTATGAGTCGGCGCGGAAACTGCTGGGATAATAGCCCAATGGAGC GCTTCTTCAGGAGTCTGAAGAACGAATGGGTGCCGGTGACGGGTTACGTAAGCTTCAGCGATGCAGTCCACGCAATAACG GACTATATCGTTGGGTATTATAGCGTGCTCAGGCCGCATGAATATAACGGTGGGTTACCACCAAACGAATCGGAAAACCG ATACCGGAAAAACTCTAACACGGTGGCCAGTTTTAGTTGA Protein sequence : MVTLCHVFGVHRSSYKYWKNRPEKPDGKRAVLRSQVLELHGISHGSAGARSIATMATQRGYQMGRWLAGRLMKELRLVSC QQPTHRYRRGGHEHVAIPNHLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFARKPVGWAMSFSPDSRLTMKALE MAWETRGKPVGVMFHSDQGSHYTSRQFRQLLWRYRIRQSMSRRGNCWDNSPMERFFRSLKNEWVPVTGYVSFSDAVHAIT DYIVGYYSVLRPHEYNGGLPPNESENRYRKNSNTVASFS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| l7094 | CAD33743.1 | ORF B protein | Not tested | PAI I 536 | Protein | 1e-96 | 88 |
| orfB | CAE85178.1 | OrfB protein, IS911 | Not tested | PAI V 536 | Protein | 1e-96 | 88 |
| orfB | AGK06910.1 | IS1359 transposase; OrfB | Not tested | SGI1 | Protein | 7e-93 | 67 |
| overlap with orfA characteristic of IS3 family members | AGK06947.1 | IS1359 transposase; OrfB | Not tested | SGI1 | Protein | 7e-93 | 67 |
| orfB | AGK06993.1 | IS1359 transposase; OrfB | Not tested | SGI1 | Protein | 7e-93 | 67 |
| orfB | AGK07051.1 | IS1359 transposase; OrfB | Not tested | SGI1 | Protein | 7e-93 | 67 |
| VC1789 | NP_231424.1 | transposase OrfAB subunit B | Not tested | VPI-2 | Protein | 9e-93 | 67 |
| orfB | ACX47958.1 | IS1359 transposase; OrfB | Not tested | SGI1 | Protein | 7e-93 | 67 |
| orfB | YP_001217329.1 | transposase OrfAB subunit B | Not tested | VPI-2 | Protein | 9e-93 | 67 |
| VPI2_0008c | ACA01825.1 | transposase OrfAB subunit B | Not tested | VPI-2 | Protein | 7e-93 | 67 |
| unnamed | AAC31485.1 | L0006 | Not tested | LEE | Protein | 5e-67 | 63 |
| ECs4537 | NP_312564.1 | hypothetical protein | Not tested | LEE | Protein | 7e-67 | 63 |
| Z5089 | NP_290241.1 | transposase | Not tested | LEE | Protein | 3e-68 | 62 |
| unnamed | ACU09432.1 | IS911 transposase orfB | Not tested | LEE | Protein | 3e-68 | 62 |
| ECO111_3779 | YP_003236114.1 | putative IS602 transposase OrfB | Not tested | LEE | Protein | 1e-70 | 62 |
| unnamed | CAI43898.1 | putative transposase | Not tested | LEE | Protein | 1e-67 | 61 |
| aec65 | AAW51748.1 | Aec65 | Not tested | AGI-3 | Protein | 1e-67 | 61 |
| RS04 | AAP82949.1 | putative transposase | Not tested | PAPI-2 | Protein | 4e-63 | 54 |
| tnpB | CAB61574.1 | transposase B | Not tested | HPI | Protein | 8e-38 | 41 |
| trp1329B | CAB46576.1 | IS1329 transposase B | Not tested | HPI | Protein | 6e-37 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Entas_4593 | YP_004821650.1 | integrase catalytic subunit | VFG1484 | Protein | 7e-97 | 88 |
| Entas_4593 | YP_004821650.1 | integrase catalytic subunit | VFG1122 | Protein | 4e-93 | 67 |
| Entas_4593 | YP_004821650.1 | integrase catalytic subunit | VFG0785 | Protein | 1e-68 | 62 |
