Gene Information

Name : Entas_4593 (Entas_4593)
Accession : YP_004821650.1
Strain :
Genome accession: NC_015963
Putative virulence/resistance : Unknown
Product : integrase catalytic subunit
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG2801
EC number : -
Position : 100576 - 101415 bp
Length : 840 bp
Strand : -
Note : KEGG: enc:ECL_A128 putative IS911 transposase orfA; manually curated; PFAM: Integrase, catalytic core

DNA sequence :
GTGGTTACTCTCTGCCACGTGTTCGGGGTTCATCGCAGTAGCTACAAATACTGGAAAAACCGTCCTGAAAAGCCAGACGG
CAAACGGGCTGTATTACGCAGCCAGGTACTTGAGCTACATGGCATCAGCCACGGTTCTGCCGGAGCAAGAAGCATCGCCA
CAATGGCCACTCAGAGAGGCTACCAGATGGGGCGCTGGCTCGCTGGCAGACTCATGAAAGAGCTGAGGCTGGTCAGTTGC
CAGCAGCCGACTCACCGGTACAGGCGTGGCGGTCATGAGCACGTTGCTATCCCGAATCATCTTGAGCGACAGTTCGCCGT
AACAGAGCCAAACCAGGTGTGGTGCGGTGATGTGACCTATATCTGGACAGGTAAGCGCTGGGCGTACCTTGCTGTTGTTC
TCGACCTGTTCGCAAGGAAACCAGTAGGCTGGGCAATGTCGTTCTCACCGGACAGCAGACTCACTATGAAAGCGCTGGAA
ATGGCATGGGAAACGCGCGGCAAGCCCGTTGGAGTAATGTTCCACAGCGATCAAGGTAGTCATTATACGAGCAGGCAGTT
CCGGCAGTTACTGTGGCGATACCGGATCAGACAGAGTATGAGTCGGCGCGGAAACTGCTGGGATAATAGCCCAATGGAGC
GCTTCTTCAGGAGTCTGAAGAACGAATGGGTGCCGGTGACGGGTTACGTAAGCTTCAGCGATGCAGTCCACGCAATAACG
GACTATATCGTTGGGTATTATAGCGTGCTCAGGCCGCATGAATATAACGGTGGGTTACCACCAAACGAATCGGAAAACCG
ATACCGGAAAAACTCTAACACGGTGGCCAGTTTTAGTTGA

Protein sequence :
MVTLCHVFGVHRSSYKYWKNRPEKPDGKRAVLRSQVLELHGISHGSAGARSIATMATQRGYQMGRWLAGRLMKELRLVSC
QQPTHRYRRGGHEHVAIPNHLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFARKPVGWAMSFSPDSRLTMKALE
MAWETRGKPVGVMFHSDQGSHYTSRQFRQLLWRYRIRQSMSRRGNCWDNSPMERFFRSLKNEWVPVTGYVSFSDAVHAIT
DYIVGYYSVLRPHEYNGGLPPNESENRYRKNSNTVASFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
l7094 CAD33743.1 ORF B protein Not tested PAI I 536 Protein 1e-96 88
orfB CAE85178.1 OrfB protein, IS911 Not tested PAI V 536 Protein 1e-96 88
orfB ACX47958.1 IS1359 transposase; OrfB Not tested SGI1 Protein 7e-93 67
orfB YP_001217329.1 transposase OrfAB subunit B Not tested VPI-2 Protein 9e-93 67
VPI2_0008c ACA01825.1 transposase OrfAB subunit B Not tested VPI-2 Protein 7e-93 67
orfB AGK06910.1 IS1359 transposase; OrfB Not tested SGI1 Protein 7e-93 67
overlap with orfA characteristic of IS3 family members AGK06947.1 IS1359 transposase; OrfB Not tested SGI1 Protein 7e-93 67
orfB AGK06993.1 IS1359 transposase; OrfB Not tested SGI1 Protein 7e-93 67
orfB AGK07051.1 IS1359 transposase; OrfB Not tested SGI1 Protein 7e-93 67
VC1789 NP_231424.1 transposase OrfAB subunit B Not tested VPI-2 Protein 9e-93 67
unnamed AAC31485.1 L0006 Not tested LEE Protein 5e-67 63
ECs4537 NP_312564.1 hypothetical protein Not tested LEE Protein 7e-67 63
Z5089 NP_290241.1 transposase Not tested LEE Protein 3e-68 62
unnamed ACU09432.1 IS911 transposase orfB Not tested LEE Protein 3e-68 62
ECO111_3779 YP_003236114.1 putative IS602 transposase OrfB Not tested LEE Protein 1e-70 62
unnamed CAI43898.1 putative transposase Not tested LEE Protein 1e-67 61
aec65 AAW51748.1 Aec65 Not tested AGI-3 Protein 1e-67 61
RS04 AAP82949.1 putative transposase Not tested PAPI-2 Protein 4e-63 54
trp1329B CAB46576.1 IS1329 transposase B Not tested HPI Protein 6e-37 41
tnpB CAB61574.1 transposase B Not tested HPI Protein 8e-38 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Entas_4593 YP_004821650.1 integrase catalytic subunit VFG1484 Protein 7e-97 88
Entas_4593 YP_004821650.1 integrase catalytic subunit VFG1122 Protein 4e-93 67
Entas_4593 YP_004821650.1 integrase catalytic subunit VFG0785 Protein 1e-68 62