Gene Information

Name : Thewi_0667 (Thewi_0667)
Accession : YP_004819404.1
Strain : Thermoanaerobacter wiegelii Rt8.B1
Genome accession: NC_015958
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 689967 - 691505 bp
Length : 1539 bp
Strand : +
Note : TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal; HAMAP: GMP synthase [glutamine-hydrolyzing]; KEGG: tbo:Thebr_1759 GMP synthase large subunit; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA methyl transfer

DNA sequence :
ATGGGGATTAAACGTGAAGTAGTGCTTATTTTAGATTTTGGAGGGCAGTATACCCAATTAATTGCCAGAAGAATAAGAGA
AGCAAATGTCTTTTGTGAAATTGTTCCTTACAATATTTCTCCAGAGGAAATACGAAAAAAAGAGCCAAAGGGAATTGTGC
TTTCTGGAGGGCCAGCCAGTGTCTACGTACAAAATGCTCCTAAGTGTGATAAAGAAATTTTTGAATTGGGCTATCCTGTA
TTAGGGATATGTTATGGCGCACAGCTTATGACAGAGCTTTTAGGTGGAAAAGTGGCTCCAGCCCCTGTAAAGGAATATGG
CAAGACAGAAATTGTATTAAACAATACTATTCCTTTGTTTAAAGGCATAGAAAGAGACACTATTGTTTGGATGAGCCATA
CTGATCAAATAGAACTTCCTCCTCCAGATTTTAAGGTAGTAGCTTCTACTGACAATTGCCCTATCGCAGCGATTGCGAAT
GTAGAGAAAAAGTTGTATGCGGTTCAATTCCACCCTGAAGTTTCACACACTCATAGAGGGACAGAGATTATAAGAAATTT
CCTCTTTGAAGTATGTGATTGCGCGGCAGATTGGACAATGGATTCTTTGATTGAGCAGACAGTAAAGGAAATAAAAGCGA
AAGTGGGAAAACACAAAGCTGTATGTGCTCTGTCTGGTGGTGTAGATTCTTCAGTTGCTGCTGTTTTAGTAGACAGAGCC
ATTCACGACCAATTGGTGTGCATTTTTGTTGATACAGGGCTTTTAAGGAAAAATGAAGGAGATATGGTTATTGAAACCTT
TAGAAAAAATTATGACATGAACATAATCCGGGTAGATGCAAGGGATAGATTTTTGTCCCGCCTTAAAGGAGTTACGGATC
CAGAAGAAAAGAGAAAAATTATTGGTAATGTTTTTATAGAAGTTTTTAAAGAAGAGGCTTTAAAGATAGGAGATGTGAAA
TTTTTGGTGCAAGGTACTTTGTATCCTGATGTAATAGAAAGTGGCAATGGCGTGTCTTCTACTATTAAAAGTCACCACAA
TGTTGGAGGTTTGCCTGAAGATATAGGTTTTGAACTTATTGAACCTTTGAGGATGCTCTTTAAAGATGAAGTAAGGCAAG
TAGGAAAAGAATTAGGAATCCCTGAGGAGATATTATATAGGCAGCCTTTCCCTGGACCAGGCCTTGCAGTCAGAATTCTT
GGAGAAGTTACAGAAGAAAAGTTAGAAATTTTGAGACAAGCTGACAGCATAGTTTTAAGGGAAATGAAAAAGTTTGGCTG
GTACAATAAAGTATGGCAATCTTTTGCGATTTTGCCTGGCATAAAAAGTGTTGGAGTTATGGGGGATGAAAGGACTTACG
CCTATGCGATAGTTTTGAGAGTAGTAGATAGCTACGACGGGATGACGGCGGATTGGACAAAGCTTCCTTATGAAATTTTG
GAGAGCATATCTACAAGCATTACTAATGAAGTGCCAGGAGTAAACAGAGTGCTTTACGATATTACTTCGAAACCACCAGC
TACCATAGAGTGGGAATAA

Protein sequence :
MGIKREVVLILDFGGQYTQLIARRIREANVFCEIVPYNISPEEIRKKEPKGIVLSGGPASVYVQNAPKCDKEIFELGYPV
LGICYGAQLMTELLGGKVAPAPVKEYGKTEIVLNNTIPLFKGIERDTIVWMSHTDQIELPPPDFKVVASTDNCPIAAIAN
VEKKLYAVQFHPEVSHTHRGTEIIRNFLFEVCDCAADWTMDSLIEQTVKEIKAKVGKHKAVCALSGGVDSSVAAVLVDRA
IHDQLVCIFVDTGLLRKNEGDMVIETFRKNYDMNIIRVDARDRFLSRLKGVTDPEEKRKIIGNVFIEVFKEEALKIGDVK
FLVQGTLYPDVIESGNGVSSTIKSHHNVGGLPEDIGFELIEPLRMLFKDEVRQVGKELGIPEEILYRQPFPGPGLAVRIL
GEVTEEKLEILRQADSIVLREMKKFGWYNKVWQSFAILPGIKSVGVMGDERTYAYAIVLRVVDSYDGMTADWTKLPYEIL
ESISTSITNEVPGVNRVLYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-148 57
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-148 57
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-148 57
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-136 53