Gene Information

Name : Thewi_2696 (Thewi_2696)
Accession : YP_004821297.1
Strain : Thermoanaerobacter wiegelii Rt8.B1
Genome accession: NC_015958
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 2760072 - 2761400 bp
Length : 1329 bp
Strand : -
Note : TIGRFAM: DNA helicase, DnaB type; PFAM: DNA helicase, DnaB-like, C-terminal; DNA helicase, DnaB-like, N-terminal; KEGG: thx:Thet_2436 replicative DNA helicase; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGGAGTGGAGCAAAATCCCTCCCCAAAACATAGAAGCTGAACAATCCGTCTTAGGGTCAATGCTTTTATCTAGGGATGC
TATAATAGACGTTTCTGAAATAATAAAAGCCGACGACTTTTATAAAGAATCCCACAAAAAATTATTCGATGTAATGATGG
AGATGTTTGAAAAAGACATCCCCGTTGACCTTGTGACAGTAGTTGATGAACTTAGAAAGCGAAACATGCTGGAGGCTGTT
GGCGGAATTGATTATATAGCAAGCCTGTCTTCCAATGTTATTACCACTGCTAACGTATCTTACTATGCAAAGCTTATAAA
AGAAAAGGCCACATTGAGAAGGCTCATTGAGGCCTCTTCAGAGATTATGGAGTTAAGTTACGAAGGGGATGACGTAGAAA
CTGTCCTTGACATAGCAGAACAAAAAATATTTGATATAGCTCAAGGAAGAAACACTACTAATTTTTCACCTATAAAAGAC
GTGTTAATGAATACCTTTTATAAAATAGAAGAACTTTACAAAAACAAAGGACAGCTTACGGGAATTCCCTCTGGCTTTCC
TGACCTTGACTTAAAAACTGCCGGCTTTCAGCCCTCTGACTTTATATTAGTCGCAGCAAGACCTTCAATGGGAAAAACCT
CTTTTGCTTTAAATATTGCTCAAAATGCAGCTCTTTTGACAGGCCTTCCTGTTGCCATATTTAGCTTAGAGATGTCAAAA
GAGCAGTTGGTAAACAGGCTTATCTGTTCTACTGCCAATATAGATAGCCAAAAGCTTAGGACAGGAAACCTTGATGAAGA
TGACTGGATGAAACTGGCAGCTGCGATGACTCCTCTTTCTAAAGCTCCTATCTATATTGATGATACCCCTGGAATTGGCG
TAATGGACATAAGGGCGAAGTGCCGGCGTCTTAAACTGGAAAAAGGATTGGGCTTGGTGATGATAGATTATCTGCAGCTT
ATGCAGGGAAGAGGAAGGGCAGAAAACAGGCAACAAGAAATTTCAGAAATATCGAGGTCTCTTAAAAGTTTAGCAAGAGA
ACTCAATGTTCCTGTAATCACCCTTTCACAGCTTTCCCGTGCACCTGAGTCCAGGTCAGACCACAGACCTATTTTAAGCG
ATTTGAGAGAATCTGGAGCAATAGAGCAGGACGCTGACATAGTAATGTTTTTGTACAGAGATGATTACTATCATAAAGAT
TCTGAAAAGAAAAACATAGCAGAAGTTATAATTGCAAAACACAGAAATGGGCCCACAGGGACAGTGGAACTTTTATGGCT
TGCACAGTATACAAAATTTGTAAGTCTTGATAAATATAGAACGGAATAA

Protein sequence :
MEWSKIPPQNIEAEQSVLGSMLLSRDAIIDVSEIIKADDFYKESHKKLFDVMMEMFEKDIPVDLVTVVDELRKRNMLEAV
GGIDYIASLSSNVITTANVSYYAKLIKEKATLRRLIEASSEIMELSYEGDDVETVLDIAEQKIFDIAQGRNTTNFSPIKD
VLMNTFYKIEELYKNKGQLTGIPSGFPDLDLKTAGFQPSDFILVAARPSMGKTSFALNIAQNAALLTGLPVAIFSLEMSK
EQLVNRLICSTANIDSQKLRTGNLDEDDWMKLAAAMTPLSKAPIYIDDTPGIGVMDIRAKCRRLKLEKGLGLVMIDYLQL
MQGRGRAENRQQEISEISRSLKSLARELNVPVITLSQLSRAPESRSDHRPILSDLRESGAIEQDADIVMFLYRDDYYHKD
SEKKNIAEVIIAKHRNGPTGTVELLWLAQYTKFVSLDKYRTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 5e-73 43
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 3e-70 42
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 2e-75 42