Gene Information

Name : Thewi_2289 (Thewi_2289)
Accession : YP_004820921.1
Strain : Thermoanaerobacter wiegelii Rt8.B1
Genome accession: NC_015958
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain-containing protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2328455 - 2330905 bp
Length : 2451 bp
Strand : -
Note : KEGG: tbo:Thebr_0352 ATPase AAA-2 domain-containing protein; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; UvrB/UvrC protein; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGGCGATGTTTGGAAGATTTACAGAAAGAGCTCAAAAAGCTCTTTATTTGGCTCAAGAGGAAGCGAGGTCTTTTTATCA
TAACTATGTAGGGACAGAACACATTTTATTAGGATTGTTAAAAGAAGATGAAGGAATTGCAGCAAGAGTTTTAAAAAAAC
TGGGAGTAACTTATGAAACTACAAGAGAGAAGGTATTGTCTTTGATTGGAATGGGAAATATTCCAGGAGACGTCGTAGGT
TATACCCCTCGGGCAAAAAGAGTACTAGAGCTAAGTCTTAGTGAGGCAAGGAGATTTAATACCAGCTATGTAGGGACAGA
GCATATTTTGTTAGGACTTTTAAGAGAAGGCGAAGGAGTTGCTGTAAGAATTTTAATGGAACAAGGTATAGATTTCAATA
GGGTGAGAGAGGAGATTGTAAAAATGCTTAATGAAGAGCCTGCAGGAGGACCTGCAAAGGCTGCAAAAGTTAAAAATACC
AATACACCTACTTTAAATCAATTTGGAAGAGATTTAACTGAGCTTGCAAGAGACGGCAAACTTGACCCTGTAATAGGAAG
AGAAAAAGAGATTGAAAGAGTTATACAAATCTTAAGCAGAAGGACAAAGAATAACCCTGTCCTAATAGGTGAACCGGGTG
TCGGTAAAACTGCTATTGTAGAAGGTCTTGCGCAAAAGATTGTAGAAGGAGAAATTCCTGAAATTTTGAAAGATAAAAGA
GTTGTAACTTTAGACATGGCTTCTATGGTAGCAGGTACAAAGTACAGAGGCGAATTTGAAGATAGGTTAAAAACAGTATT
AAATGAGGTTATAAAGGCAGGAAATGTGATACTATTTATAGATGAGATGCACACTTTGATAGGAGCAGGTGCAGCAGAGG
GTGCAATAGATGCATCAAATATTCTAAAACCGGCACTTGCAAGAGGTGAAATTCAAGTAGTTGGAGCTACTACTTTGGAT
GAGTACAGAAAATATGTAGAAAGAGACCCTGCATTAGAGAGACGATTCCAACCAATAATTGTAGATGAACCAACTGTGGA
GGAGACTATTGAGATATTAAAGGGCTTGAGAGATAAGTATGAAGCCCATCATAGGGTTAAAATTACTGACGAAGCTTTAG
AAGCAGCAGCTAGACTTTCTCACAGATATATTGCAGATAGATTTTTACCTGATAAAGCTATAGACTTAATAGATGAAGCA
GCTTCTCGCGTAAGACTAAAGACAGTGACAGCTCCTCCAGAGATAAAAGAACTGGAAGATAAAATCAATGACCTTATAAA
AGAGAAGGAAGAAGCGATAAGAACTCAAGAATACGAAAAAGCTGCAAAAATAAGAGATGAAGAACAAAAATTGAGAGAAG
AATTAGAAAAATTAAAAGCTAAATGGCAACAAAATTCTCTTTCTAATGAAAAAAGTGTAGGACCTGAAGAAATCGCACAA
GTCGTATCTCTGTGGACAGGAATACCTGTTAAAAAGTTAGCTGAAGAGGAATCAGAGAGATTGCTCCACTTAGAGGAGGT
ATTGCATGAAAGAGTTATAGGACAAGATGAAGCAGTAGAAGCAGTGGCAAGAGCTATAAGAAGGGCAAGAGTAGGCTTAA
AAGATCCAAAAAGGCCAATAGGTTCATTTATCTTCTTGGGTCCTACTGGTGTTGGTAAAACAGAACTTACAAAGGCTTTG
GCAGAAGCTCTTTTTGGTGACGAAAATGCTATGATTAGGCTTGATATGTCAGAATACATGGAAAGACACACTGTATCTAA
ACTTATCGGTTCACCTCCAGGATATGTAGGATTTGAAGAAGGAGGACAATTAACAGAAAAAGTAAGAAGAAAGCCCTATT
CAGTAATCTTGCTGGATGAAATTGAAAAAGCGCATCCTGACGTGTTTAACATTCTCCTTCAAATATTAGAAGATGGACGA
CTCACAGATTCAAAAGGTAGAACTGTGGACTTTAAAAATACAGTTATAATCATGACATCAAATGTGGGAGCAGAACTTTT
GAAAAAGCAATCTACCTTAGGATTTATGCCTCAAGAAAAAGAAGACAAAGCCTCTTATGACAAAATAAAAGAAACATTGA
TGGCAGAGTTGAGAAAGACCTTTAGACCTGAATTCTTAAATAGGGTGGATGAGATAATTGTATTTCATCAACTCTCAAAA
GAAGATATTGAAAAGATTGCTGATATAATGATTAAAGAATTGAATAATAGACTAAAAGAGAACAACATTAAACTGGAGTT
TACTCCTGAAGCCAAAGAGGAAATTATCAAACAAGGATATGACCCCAACTACGGTGCAAGGCCTTTAAGAAGAGTTATAC
AAAGAATTGTAGAGAATCAATTATCAGAATTGATGTTGCAAGGGGAAGTCAAACCAGGAGATGAACTTATTGTAACTGCT
AAAGATGGTAAAATAGACTTTGTAAAAAAAGATGCTGTGCAAAAGGCTTAG

Protein sequence :
MAMFGRFTERAQKALYLAQEEARSFYHNYVGTEHILLGLLKEDEGIAARVLKKLGVTYETTREKVLSLIGMGNIPGDVVG
YTPRAKRVLELSLSEARRFNTSYVGTEHILLGLLREGEGVAVRILMEQGIDFNRVREEIVKMLNEEPAGGPAKAAKVKNT
NTPTLNQFGRDLTELARDGKLDPVIGREKEIERVIQILSRRTKNNPVLIGEPGVGKTAIVEGLAQKIVEGEIPEILKDKR
VVTLDMASMVAGTKYRGEFEDRLKTVLNEVIKAGNVILFIDEMHTLIGAGAAEGAIDASNILKPALARGEIQVVGATTLD
EYRKYVERDPALERRFQPIIVDEPTVEETIEILKGLRDKYEAHHRVKITDEALEAAARLSHRYIADRFLPDKAIDLIDEA
ASRVRLKTVTAPPEIKELEDKINDLIKEKEEAIRTQEYEKAAKIRDEEQKLREELEKLKAKWQQNSLSNEKSVGPEEIAQ
VVSLWTGIPVKKLAEEESERLLHLEEVLHERVIGQDEAVEAVARAIRRARVGLKDPKRPIGSFIFLGPTGVGKTELTKAL
AEALFGDENAMIRLDMSEYMERHTVSKLIGSPPGYVGFEEGGQLTEKVRRKPYSVILLDEIEKAHPDVFNILLQILEDGR
LTDSKGRTVDFKNTVIIMTSNVGAELLKKQSTLGFMPQEKEDKASYDKIKETLMAELRKTFRPEFLNRVDEIIVFHQLSK
EDIEKIADIMIKELNNRLKENNIKLEFTPEAKEEIIKQGYDPNYGARPLRRVIQRIVENQLSELMLQGEVKPGDELIVTA
KDGKIDFVKKDAVQKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 57
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-95 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thewi_2289 YP_004820921.1 ATPase AAA-2 domain-containing protein VFG0079 Protein 0.0 63
Thewi_2289 YP_004820921.1 ATPase AAA-2 domain-containing protein VFG0080 Protein 2e-149 55