Gene Information

Name : Thewi_1786 (Thewi_1786)
Accession : YP_004820461.1
Strain : Thermoanaerobacter wiegelii Rt8.B1
Genome accession: NC_015958
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1791206 - 1792957 bp
Length : 1752 bp
Strand : -
Note : KEGG: thx:Thet_1715 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region

DNA sequence :
ATGCGCAGAACAAAAATAGTGTGTACAATAGGACCTGCCAGCGAAGACTATAATATACTGAGAAAATTAATTGAGAAGGG
CATGAACGTTGCTCGATTGAATTTTTCTCATGGAGATTTTGAAGAGCATGGGGCAAGAATTGACAATATTAAAAAGATAA
GAGAAGAATTAGGGTTACCTGTTGCTATTTTGTTGGATACTAAAGGTCCAGAGATAAGGACAGGAAAGTTTAAAAATGGC
GGAGTGGAATTAAAAGAAGGACAAACTTTTGTCATTACGACAAGAGATGTATTAGGAGACGAAACTATATGCAGTGTATC
CTATAAAGGGTTGCCTCAAGATGTGGAAAGAGGTAGCCGCATATTAATTGACGATGGGTTAATTTCTCTAAAGGTTACTG
ATGTTAAAGGAGAAGATATAGTTTGTATTGTAGAAAATTCTGGTGCTGTAAAAGACCATAAAGGAGTAAATGTTCCAGGA
GTAAAACTCAATCTTCCTGCTTTGACTCAAAAAGACGTAGATGATATAGAGTTTGGAATTCAAAAGGGCATTGATATAAT
TGCGGCTTCTTTTGTTAGAAAAGCAGCTGATGTTTTGGCAATAAGAAGACTTTTAGAAGAAAATAAGGCAGAGCATATTT
TAATTATTGCTAAAATAGAAAATCGCGAAGGAGTAGAAAATATAGACGAAATTATAAAGGTTTCAGATGGAATAATGGTA
GCCAGAGGAGATTTAGGGGTTGAGATTCCTCTTGAAGAAATACCAATCGTTCAAAAAATGATTATACAAAAATGTAATAA
AGCAGGGAAACCGGTAATTACTGCAACTCAAATGTTAGACTCTATGATGAGAAATCCAAGGCCTACAAGAGCAGAAGTTA
CAGATGTAGCAAATGCTATTCTTGATGGAACAGATGCTATAATGCTATCAGGGGAGACAGCTCAAGGTAAATACCCAATA
GAGGCCTTTGAGACAATGGCAAAGATTGCAGAAAAGACAGAGGCTTATGTGGGATATAGAGATATCATTGATAGAAATAT
TGATACAAATGTTTCTATTACAAACGCTATAAGCCATGCAACTTGTACTACTGCAAGAGATATAGGAGCAGCTGCTATAA
TAACTTGTACTAAATCTGGTTATACAGCGAGAATGGTATCGAGGTACAGACCTCAAGCTCCAATTATTGCTACTACTCCA
AGCGAAAGTGTTGCGAGGAAGCTCTCTATAGTCTGGGGAGTATATCCTTTAGTTACAGAAGAGGTTTCTACTACAGATGA
AATGATAGATGTTGCAATACAAAGTGCTTTAACTGCTGGACTTATAAGAAATGGCGATATCGTAGTAATTTCTGCAGGAA
TTCCTGTAGCTATGACAGGTACCACCAACATGTTGAAGGTACATATAGTAGGAGATGTTTTGTTGAGAGGAATAGGTATA
GGTTCTAAGGCTACTACAGGTGTTGTATGTGTTATTAATGATATCAGCAAAGACAAAGATAAATTTAGAGAAGGCGATAT
AATAGTAACTGCAAAGACAGAAAGAGATTTTATGCCTCTTATAGAGAAAGCTTCTGCTATAATCACAGAAGAAGGAGGGC
TTACTTCTCACGCAGCTATTGTGGGATTAAACTTAGGAATTCCTGTAGTTGTAGGTTGTGAAGGAGCGACTTCTAAATTA
AAAGATGGCATGACTGTAACGGTTGACACAGTTAGAGGATTTGTGTATAAAGGAATTGTAAATATTAAATAA

Protein sequence :
MRRTKIVCTIGPASEDYNILRKLIEKGMNVARLNFSHGDFEEHGARIDNIKKIREELGLPVAILLDTKGPEIRTGKFKNG
GVELKEGQTFVITTRDVLGDETICSVSYKGLPQDVERGSRILIDDGLISLKVTDVKGEDIVCIVENSGAVKDHKGVNVPG
VKLNLPALTQKDVDDIEFGIQKGIDIIAASFVRKAADVLAIRRLLEENKAEHILIIAKIENREGVENIDEIIKVSDGIMV
ARGDLGVEIPLEEIPIVQKMIIQKCNKAGKPVITATQMLDSMMRNPRPTRAEVTDVANAILDGTDAIMLSGETAQGKYPI
EAFETMAKIAEKTEAYVGYRDIIDRNIDTNVSITNAISHATCTTARDIGAAAIITCTKSGYTARMVSRYRPQAPIIATTP
SESVARKLSIVWGVYPLVTEEVSTTDEMIDVAIQSALTAGLIRNGDIVVISAGIPVAMTGTTNMLKVHIVGDVLLRGIGI
GSKATTGVVCVINDISKDKDKFREGDIIVTAKTERDFMPLIEKASAIITEEGGLTSHAAIVGLNLGIPVVVGCEGATSKL
KDGMTVTVDTVRGFVYKGIVNIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-106 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 9e-107 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 9e-107 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-106 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thewi_1786 YP_004820461.1 pyruvate kinase VFG0479 Protein 4e-107 51