Gene Information

Name : Thewi_1394 (Thewi_1394)
Accession : YP_004820100.1
Strain : Thermoanaerobacter wiegelii Rt8.B1
Genome accession: NC_015958
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 1399358 - 1400668 bp
Length : 1311 bp
Strand : -
Note : TIGRFAM: flagellar protein export ATPase FliI; ATPase, type III secretion system, FliI/YscN; PFAM: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; KEGG: tpd:Teth39_1254 fla

DNA sequence :
ATGAGTAATATGTTAGATAAATATAAAAAAGTTCTTCAAGAAAAAAGGCTAATTCAATATTATGGAAAAGTTTCTCAAGT
AATAGGATTAACAATCGAAAGTACAGGGCCTCTTTCCAACATAGGAGAAATATGTAATATCAAGACTATTAACGGAAATA
CAATTTTGGCAGAAGTTGTAGGTTTTAAAGAAGAAAAAGTGTATCTCATGCCTTTAGGGAATATGGAGGGAATAGGAGCA
GGCAGCAAAGTGATAGCTACAGGTCAAACACTTAGAATTAACGTAGGAAATGAACTTCTTGGAAGGGTATTAGACGGTTT
GGGCAATCCTATAGATGGCAAAGGACCGATAAAATTTGAAAAATCTATTCCTATTAATAATGTGCCGCCTGATCCTTTAG
AAAGGAAGCGAATTAGAGAAGTCATTCCTCTTGGTATAAAAGCGATAGATGGACTACTTACTTGCGGCAAAGGGCAGAGA
ATTGGTATTTTTGCAGGAAGTGGTGTAGGAAAAAGTACGTTATTAGGTATGATGGCAAGAAATGCTAAAGCTGATTTAAA
TGTAATAGCTCTTATAGGAGAAAGAGGAAGAGAGGTAAATGAATTTTTAGAAAAAGATTTAGGGGAAGAAGGTTTAAAAA
AATCTGTAGTTGTAGTAGCTACTTCTGATACTCCAGCTCTTATAAGAGTAAAAGGCGCTATGACTGCAACTGCTATAGCT
GAATATTTTAGAGACCAGGGGTTAGATGTTCTTTTGATGATGGATTCAGTAACTCGTTTTGCCATGGCTCAAAGAGAAGT
AGGGCTTTCTATAGGGGAAGCTCCTGTTTCACGAGGTTATACTCCTTCTGTCTTTTCAGTTTTACCTAAGCTTTTAGAAC
GATCTGGATGTTCTAAAAAAGGCTCTATTACAGCTCTTTACACTGTGCTAGTAGATGGGGATGATTTGAATGAGCCAATT
GCTGACGCAGTAAGGGGTATACTCGATGGGCACATAGTTTTGTCAAGGAAACTGGCTAATAAAAACCATTATCCTGCTAT
TGATGTATTAGCAAGTGTTAGCAGGGTGATAAATGACATAATTACAGAAGAACATAAAGAACTAATAGCGAGGTTTAAAG
ATATTTTGGCGACTTACACAGAAGCGGAGGATTTAATAAATATAGGAGCATATAATTTTGGCAGTAATCCTAAAATTGAT
GAAGCTATTGAGCTAAATGAAAAAATGAATAGTTTCTTAAGGCAGAGAATAGACGAATCTTATGACTTTGAAACTACAAA
ACAACTTTTATACGAATCTATTAAAAGGTGA

Protein sequence :
MSNMLDKYKKVLQEKRLIQYYGKVSQVIGLTIESTGPLSNIGEICNIKTINGNTILAEVVGFKEEKVYLMPLGNMEGIGA
GSKVIATGQTLRINVGNELLGRVLDGLGNPIDGKGPIKFEKSIPINNVPPDPLERKRIREVIPLGIKAIDGLLTCGKGQR
IGIFAGSGVGKSTLLGMMARNAKADLNVIALIGERGREVNEFLEKDLGEEGLKKSVVVVATSDTPALIRVKGAMTATAIA
EYFRDQGLDVLLMMDSVTRFAMAQREVGLSIGEAPVSRGYTPSVFSVLPKLLERSGCSKKGSITALYTVLVDGDDLNEPI
ADAVRGILDGHIVLSRKLANKNHYPAIDVLASVSRVINDIITEEHKELIARFKDILATYTEAEDLINIGAYNFGSNPKID
EAIELNEKMNSFLRQRIDESYDFETTKQLLYESIKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 6e-108 54
escN CAI43874.1 EscN protein Virulence LEE Protein 9e-94 52
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-93 52
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-90 52
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-90 52
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-103 52
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-103 52
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-102 52
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-103 52
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-103 52
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 3e-103 52
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-103 52
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-100 51
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-100 51
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-93 50
escN AAC38383.1 EscN Virulence LEE Protein 2e-93 50
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-93 50
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-93 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-93 50
escN AAC31513.1 L0034 Virulence LEE Protein 3e-93 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 5e-94 50
escN AAK26715.1 EscN Virulence LEE Protein 2e-93 49
escN AAL57542.1 EscN Virulence LEE Protein 2e-93 49
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-93 49
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-93 49
unnamed AAL06369.1 EscN Virulence LEE Protein 6e-92 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-87 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-85 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 6e-87 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-87 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-85 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 7e-80 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-79 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-83 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 5e-84 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-84 46
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-91 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-79 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-79 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-87 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 8e-82 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-82 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-82 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-75 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-73 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-73 42
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-73 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-73 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 1e-75 42
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 7e-72 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG2144 Protein 1e-112 57
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG0048 Protein 2e-108 56
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG0390 Protein 4e-106 53
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG0192 Protein 4e-110 52
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG0812 Protein 2e-93 50
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG0730 Protein 1e-93 50
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG1254 Protein 8e-103 49
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG0515 Protein 4e-87 49
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG2331 Protein 4e-94 48
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG2499 Protein 5e-96 48
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG1008 Protein 4e-73 44
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG2459 Protein 6e-81 43
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG1778 Protein 6e-73 43
Thewi_1394 YP_004820100.1 flagellar protein export ATPase FliI VFG0555 Protein 1e-73 42