Gene Information

Name : Halar_3215 (Halar_3215)
Accession : YP_004809202.1
Strain : halophilic archaeon DL31
Genome accession: NC_015954
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 2423032 - 2424291 bp
Length : 1260 bp
Strand : +
Note : KEGG: hsl:OE2173F cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase); PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme

DNA sequence : 
ATGTACCCCATTTCAACCATGCCAGAGAATCACGACCATCGGTTTGATACCCGCGCCGTCTCCTGGGGCGAGCATCCCGA
GGGCCACGGCGTCGGCGACGTCGTCTCACCCATCCATCTGGCCTCCACCTTCGCCATCCCCGGCCTCGACCCGGATTTCA
AGCTGGACGAGGCCGACCCGCACAAGGGTGAGTTCCTCTACGGTCGACTCTCGAACCCGACGCGCCACGCGGCCGAGAAG
CGCCTCGCAGCCCTCGAAGACGGCAATCATGGACTCGCCTTCGCCTCCGGAACGGCGGCTATCTCGACGCTCTTTTTCGC
CACACTCTCGCCGGGGGACCACGTCGTCGCCTTCGACGACCTCTACGCCGGCACCCGACGGATGCTGGAGTATTACTACC
GAGACCACCTCGGCGTCGAAATCTCGTTTGTGGACGCCACGGAGACTGAGAACGTCGCCGACGCGATGCGCTCGGAAACG
GCGCTCGTCTACATGGAGACGCCGACGAACCCCCTGCTCAAGCTCTGTGATCTCGAAGCAATCGCCGACATCGCCCACGA
GGGCGACGCGCTCCTCGGCGTCGACAACACGTTCTGCTCGCCGTCCCTCCAGAACCCCCTCGACCTCGGAGCAGACGTCG
TCGCCCACAGTACGACCAAATATCTGAACGGCCACTCCGACTCTATCGGCGGTGCGCTTGTCGTCGACGACGACGACCTA
GCAGAGGAGCTCTACTTCCTCCAGCGCGTCGTGCTTGGGAACATGATGTCGCCGTTCGACGCCTACCTCACCCTCCGCGG
GACGAAGACGCTCCCGATGCGGATGCGCCAGCACGAAGCCAACGCGCAGGTCATCGCGGAGTACCTCGACGAGCACGAGC
TGGTCGAGACAGTCTACTATCCGGGCCTCGAGAGCCACCCACAACATGACCTCGCCGCCCGTCAGCAGTCGGGCTTCGGC
GGGATGCTCTCGTTCGACCTGGTCGGCGAGATGGGTGACGCCAAAGTGTTCTTAGAGAGCCTTCGGACCTTCACCCTCGC
CGTCTCGCTCGGCGGCGTCGAGTCGCTCGTGGAGCTTCCGGCAGGGATGACCCACCAGCCGATTCCGAAGGAGACACGCG
AAGCCCACGGCATCTCGGACACCCTCGTGCGGATGTCGGTCGGCGTCGAGGACATCGACGACCTCATCGCGGACCTGGAC
CGTGGCTTCGAGGCGATGGCAGGCGGCCAGGCGCTCGGCGCGGCGGCCGACGACGACTGA

Protein sequence : 
MYPISTMPENHDHRFDTRAVSWGEHPEGHGVGDVVSPIHLASTFAIPGLDPDFKLDEADPHKGEFLYGRLSNPTRHAAEK
RLAALEDGNHGLAFASGTAAISTLFFATLSPGDHVVAFDDLYAGTRRMLEYYYRDHLGVEISFVDATETENVADAMRSET
ALVYMETPTNPLLKLCDLEAIADIAHEGDALLGVDNTFCSPSLQNPLDLGADVVAHSTTKYLNGHSDSIGGALVVDDDDL
AEELYFLQRVVLGNMMSPFDAYLTLRGTKTLPMRMRQHEANAQVIAEYLDEHELVETVYYPGLESHPQHDLAARQQSGFG
GMLSFDLVGEMGDAKVFLESLRTFTLAVSLGGVESLVELPAGMTHQPIPKETREAHGISDTLVRMSVGVEDIDDLIADLD
RGFEAMAGGQALGAAADDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-59 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-60 42
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-51 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Halar_3215 YP_004809202.1 cystathionine gamma-lyase BAC0207 Protein 9e-62 42