Gene Information

Name : SACTE_4205 (SACTE_4205)
Accession : YP_004804585.1
Strain : Streptomyces sp. SirexAA-E
Genome accession: NC_015953
Putative virulence/resistance : Resistance
Product : Cys/Met metabolism pyridoxal-phosphate-dependent protein
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 4649605 - 4650750 bp
Length : 1146 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: sgr:SGR_2579 cystathionine gamma-synthase

DNA sequence : 
ATGAGCGACCAGCACAGCTTCGAGACCCTCGCGATCCACGCCGGAAACACGGCGGATCCCCTCACCGGCGCCGTGGTCCC
GCCGATCTACCAGGTGTCCACGTACAAGCAGGACGGTGTCGGCGGGCTGCGGGGCGGCTACGAGTACAGCCGCAGCGCCA
ACCCCACCCGCACCGCACTGGAGGAGAACCTGGCGGCCCTGGAAGGCGGCCGTCGCGGCCTCGCCTTCGCCTCCGGCCTC
GCCGCCGAGGACTGCCTCCTGCGGACGCTGCTCGCGCCCGGTGACCACGTCGTCATCCCGAACGACGCCTACGGCGGCAC
GTTCCGGCTGTTCGCGAAGGTCGCCTCGCGCTGGGGCGTGGAGTTCTCGGTGGCCGACACCTCGGACGTCGACGCGGTGC
GCGCGGCGATCACCCCCCGCACCAAGGCGGTCTGGGTGGAGACCCCGTCCAACCCGCTGCTCGGCATCACCGACATCGCG
GCCGTCGCGGGTGTGGCCCGGCAGGCGGGCGTGCGGCTCGTCGTCGACAACACCTTCGCCAGCCCCTACCTCCAGCAGCC
GCTCGCGCTCGGCGCGGACGTCGTGGTGCACTCCACCACCAAGTACATGGGCGGGCACTCGGACGTGGTCGGCGGTGCGC
TGGTCACCGACGACCCCCAGCTCGCCGATGAACTGGTGTACCACCAGAACGCGATGGGCGCCGTCGCCGGGCCGTTCGAC
GCGTGGCTGGTGCTGCGCGGCATCAAGACGCTGGCGGTGCGCATGGACCGCCACGACGAGAACGCCACCAAGGTGGCCGA
CCTGCTGACCCGGCACCCCAAGGTGAGCCAGGTCCTCTACCCGGGTCTGCCGGAGCACCCGGGGCACGAGGTCGCCGCCA
AGCAGATGAAGGCGTTCGGCGGGATGGTGTCCTTCCGCGTCGCGGGCGGCGAGGAGGCGGCGGTCGAGGTCTGCAACCGG
GCGAAGCTGTTCACGCTCGGTGAGTCCCTCGGCGGTGTGGAGTCGCTGATCGAGCACCCGGGCCGGATGACGCACGCGTC
CACCGCCGGTTCCCTGCTGGAGGTGCCGGCCGACCTGGTCCGGCTGTCCGTCGGCATCGAGAACGCCGACGACCTGCTGG
CCGACCTCACCCAGGCGCTCGGCTGA

Protein sequence : 
MSDQHSFETLAIHAGNTADPLTGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRTALEENLAALEGGRRGLAFASGL
AAEDCLLRTLLAPGDHVVIPNDAYGGTFRLFAKVASRWGVEFSVADTSDVDAVRAAITPRTKAVWVETPSNPLLGITDIA
AVAGVARQAGVRLVVDNTFASPYLQQPLALGADVVVHSTTKYMGGHSDVVGGALVTDDPQLADELVYHQNAMGAVAGPFD
AWLVLRGIKTLAVRMDRHDENATKVADLLTRHPKVSQVLYPGLPEHPGHEVAAKQMKAFGGMVSFRVAGGEEAAVEVCNR
AKLFTLGESLGGVESLIEHPGRMTHASTAGSLLEVPADLVRLSVGIENADDLLADLTQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-74 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-76 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-56 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SACTE_4205 YP_004804585.1 Cys/Met metabolism pyridoxal-phosphate-dependent protein BAC0207 Protein 3e-57 44