Gene Information

Name : SACTE_2519 (SACTE_2519)
Accession : YP_004802947.1
Strain : Streptomyces sp. SirexAA-E
Genome accession: NC_015953
Putative virulence/resistance : Unknown
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 2839787 - 2841130 bp
Length : 1344 bp
Strand : +
Note : TIGRFAM: nucleotide sugar dehydrogenase; KEGG: sgr:SGR_4481 putative UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase

DNA sequence :
ATGGCCCTCAGGATCACTGTGATCGGCACCGGCTACCTCGGCGCCACCCATGCCGCGGCCATGGCGGAGCTGGGATTCGA
GGTCCTGGGGCTGGACGTGGTGCCCGAGAAGATCGAGATGCTCTCGGCGGGCAAGGTGCCGATGTACGAACCAGGGCTGG
AGGAGATCCTGCGCAAGCACGTCGCGGGCATCGAGGGCTCCACCGGGCGGCTGCGGTTCACGACCTCCTGGGAGGAGGCC
GGGGCCTTCGGCGACGTCCACTTCGTCTGTGTGAACACCCCGCAGAAGCACGGCGAGTACGCCTGCGACATGAGCTACGT
GGACAGCGCCTTCGAATCGCTGGCCCCGCAGCTGACGCGGCCCGCGCTGGTGGTCGGCAAGTCCACCGTGCCGGTGGGAT
CCGCCGCCCGGCTGGCCGAGCGGCTGGCCGCACTGGCCCCGGCGGGCGCCGATGTGGAGCTGGCCTGGAACCCGGAGTTC
CTGCGCGAGGGCTTCGCGGTGGACGACACCCTGCACCCCGACCGGATCGTGGTGGGCGTACGGAGCGAGCGGGCCGAGAA
GCTGCTGCGCGAGGTGTACGCGGGACCGGTCGGCGAGGGCTCGCCCTTCGTGGTGACGGACTTCCCGACGGCGGAGCTGG
TGAAGACCTCGGCCAACTCCTTCCTGGCCACCAAGATCTCGTTCATCAACGCCATGGCGGAGGTCTGCGAGGCCGCCGAC
GGTGACGTGGTGAAGCTGGCGGAGGCGCTCGGCCACGACGAGCGGATCGGGAAAAAGTTCCTGCGGGCCGGCGTCGGGTT
CGGCGGCGGGTGCCTGCCGAAGGACATCCGGGCCTTCATGGCGCGGGCCGGGGAGCTCGGGGCCGACCAGGCGCTGACCT
TCCTGCGCGAGGTCGACTCGATCAACATGCGCCGCCGCGGGCACATGGTCGAGCTGGCGCGCGAGGCGGTGGGCGGCGGC
TCGTTCCTGGGGAAGCGGGTGGCGGTGCTGGGTGCCTCGTTCAAGCCGGACTCGGACGACGTACGCGACTCGCCCGCGCT
GAACGTGGCCGGGCAGATCCACCTCCAGGGCGGCCAGGTCACCGTCTTCGACCCCAAGGGCATGGACAACGCCCGGCGGC
TGTTCCCGACGCTCGGCTACGCGGACACGGCACTGGACGCGGTGCGCGGCGCCGACGTGGTGCTGCACCTGACGGAGTGG
CGCGAGTTCCGGGAGCTGGACGTCGAGGCGCTGGGCGAGGTCGCCGGGCGGCGGATCGTCCTGGACGGCCGCAACGCGCT
GGACCCGGCGGTGTGGCGTGCCGCGGGCTGGACGTACCGGGCGATGGGCCGCCCCAAGGCCTGA

Protein sequence :
MALRITVIGTGYLGATHAAAMAELGFEVLGLDVVPEKIEMLSAGKVPMYEPGLEEILRKHVAGIEGSTGRLRFTTSWEEA
GAFGDVHFVCVNTPQKHGEYACDMSYVDSAFESLAPQLTRPALVVGKSTVPVGSAARLAERLAALAPAGADVELAWNPEF
LREGFAVDDTLHPDRIVVGVRSERAEKLLREVYAGPVGEGSPFVVTDFPTAELVKTSANSFLATKISFINAMAEVCEAAD
GDVVKLAEALGHDERIGKKFLRAGVGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRGHMVELAREAVGGG
SFLGKRVAVLGASFKPDSDDVRDSPALNVAGQIHLQGGQVTVFDPKGMDNARRLFPTLGYADTALDAVRGADVVLHLTEW
REFRELDVEALGEVAGRRIVLDGRNALDPAVWRAAGWTYRAMGRPKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
udgA YP_005682185.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 7e-76 49
udgA YP_003784334.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 7e-76 49
udgA YP_005686369.1 UDP-glucose 6-dehydrogenase Not tested PiCp 7 Protein 7e-76 49