Gene Information

Name : SACTE_2480 (SACTE_2480)
Accession : YP_004802908.1
Strain : Streptomyces sp. SirexAA-E
Genome accession: NC_015953
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2786499 - 2787176 bp
Length : 678 bp
Strand : -
Note : KEGG: sgr:SGR_4523 putative two-component system response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver

DNA sequence : 
ATGAAGGGACGCGTCCTTGTCGTCGACGACGACACCGCGCTGGCCGAGATGCTCGGCATTGTGCTGCGTGGAGAAGGTTT
CGAGCCATCGTTCGTAGCGGACGGCGACAAGGCACTGGCTGCATTTCGTGACGCCAAGCCGGACCTGGTGCTGCTGGACC
TCATGCTGCCCGGACGGGACGGCATCGAGGTCTGCAGGCTGATCCGGGCCGAGTCGGGTGTGCCGATCGTCATGCTCACC
GCCAAGAGCGACACGGTCGACGTGGTGGTGGGTCTGGAGTCAGGGGCCGACGACTACATCGTCAAGCCGTTCAAGCCGAA
GGAGTTGGTCGCCCGGATCAGGGCACGTCTGCGGAGGTCCGAGGAGCCCGCGCCGGAGCAGCTGGCGATCGGTGACCTGG
TCATCGATGTGGCCGGGCACTCGGTGAAGCGGGAGGGCCAGTCCATCGCGCTCACCCCGCTGGAGTTCGACCTGCTGGTG
GCCCTCGCCCGTAAGCCGTGGCAGGTCTTCACCCGTGAGGTGCTGCTCGAGCAGGTATGGGGGTACCGGCACGCCGCGGA
CACCCGGCTGGTGAACGTGCATGTGCAGCGGCTCCGTTCCAAGGTCGAGAAGGACCCGGAGCGGCCGGAGATCGTCGTGA
CCGTCCGCGGTGTCGGTTACAAGGCCGGACCGAGCTGA

Protein sequence : 
MKGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFRDAKPDLVLLDLMLPGRDGIEVCRLIRAESGVPIVMLT
AKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARLRRSEEPAPEQLAIGDLVIDVAGHSVKREGQSIALTPLEFDLLV
ALARKPWQVFTREVLLEQVWGYRHAADTRLVNVHVQRLRSKVEKDPERPEIVVTVRGVGYKAGPS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 2e-37 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator AE000516.2.gene3505. Protein 1e-79 75
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_012469.1.7685629. Protein 3e-45 46
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator BAC0125 Protein 9e-34 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_002952.2859905.p0 Protein 5e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_002745.1124361.p0 Protein 8e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_009782.5559369.p0 Protein 8e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_002951.3237708.p0 Protein 8e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_003923.1003749.p0 Protein 6e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_002758.1121668.p0 Protein 8e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_007622.3794472.p0 Protein 5e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_009641.5332272.p0 Protein 8e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_013450.8614421.p0 Protein 8e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_007793.3914279.p0 Protein 8e-46 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator HE999704.1.gene2815. Protein 4e-42 45
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_012469.1.7686381. Protein 4e-42 44
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_010079.5776364.p0 Protein 4e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_002952.2859858.p0 Protein 4e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_007622.3794948.p0 Protein 4e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_003923.1003417.p0 Protein 4e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_013450.8614146.p0 Protein 4e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_002951.3238224.p0 Protein 4e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_007793.3914065.p0 Protein 4e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_002758.1121390.p0 Protein 4e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator AE015929.1.gene1106. Protein 7e-36 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator BAC0039 Protein 2e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator CP001918.1.gene3444. Protein 1e-39 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator CP001138.1.gene2239. Protein 3e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator CP000034.1.gene2186. Protein 2e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator NC_002695.1.916589.p Protein 2e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator BAC0596 Protein 3e-40 43
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator AE016830.1.gene1681. Protein 4e-41 42
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator HE999704.1.gene1528. Protein 1e-34 41
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator AF155139.2.orf0.gene Protein 2e-35 41
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator FJ349556.1.orf0.gene Protein 1e-36 41
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator BAC0197 Protein 5e-32 41
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator CP000034.1.gene3671. Protein 4e-37 41
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator CP000647.1.gene2531. Protein 8e-39 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator VFG1390 Protein 2e-35 44
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator VFG1389 Protein 8e-32 44
SACTE_2480 YP_004802908.1 winged helix family two component transcriptional regulator VFG1702 Protein 8e-38 41