Gene Information

Name : SACTE_1433 (SACTE_1433)
Accession : YP_004801890.1
Strain : Streptomyces sp. SirexAA-E
Genome accession: NC_015953
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1599848 - 1601281 bp
Length : 1434 bp
Strand : -
Note : TIGRFAM: pyruvate kinase; KEGG: sgr:SGR_5516 putative pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
ATGCGCCGAGCGAAAATCGTTTGTACCCTGGGCCCCGCAACCGACACATACGACCAGATCAAGGCATTGGTCGAAGCGGG
AATGGACATCGCCCGCCTCAACCTCAGCCACGGCACCTACGCCGAACACGAAGAGCGATACCACCACGTACGCAAGGCAT
CCCAGGAGACCGGCCGCAGCGTCGGAATCCTCGCCGACCTTCAAGGCCCGAAGATCCGCCTCGGCCGCTTCGCCGAAGGT
CCCGTACTCCTTGAACGCGGTGACACCTTCACCATCACCACCGAACCCGCCGAAGGTGACCGCCACACCTGCTCCACCAC
CTACGACGGCCTCGCCGCCGACGTCACCGCCGGCGAACGCGTCCTCGTCGACGACGGCCGCGTCACCCTCGAAGTCACCG
GCGTCGACGGACCCCGCGTCCGCACCACCGTCATCGAAGGCGGCATGGTCTCCGACCACAAGGGACTCAACCTCCCCGGC
GTCGCCGTCTCCGTGCCCGCACTCTCCGAGAAGGACATCGACGACCTCCGCTGGGCCCTGCGCACCGGCGCCGACGTCAT
CGCCCTCTCGTTCGTCCGCACCGGACGCGACATCGAGGACGTCCACCGCGTCATGGACGAGGAGAACCGCCGCCTCCCCG
TCATCGCCAAGGTCGAGAAACCGCAGGCCGTCGACAACATCGACGACATCGTCGCCGCCTTCGACGGCATCATGGTCGCC
CGCGGCGACCTCGGCGTCGAGATGCCCCTGGAGCAGGTCCCGATCGTCCAGAAGCGCGCCGTCAAACTCGCCAAGCGCAA
CGCCAAGCCGGTCATCGTCGCCACCCAGATGCTCGACTCGATGATCGACAACTCCCGGCCCACCCGCGCCGAGGCCTCCG
ACGTCGCCAACGCGATCATCGACGGCACGGACGCCGTCATGCTCTCCGGCGAGACCAGCGTCGGCAAGTACCCCATCGAG
ACCGTCGCCACCATGGCGCGCATCGTCGAGGCCGCCGAGGAGGACATCCTCGCCAAGGGACTCCCGCCGCTCACCGACCG
CAACAAGCCCCGCACCCAGGGCGGCGCGGTCGCCCGCGCGGCGGCGGAGATGGGCGACTTCCTCGGCGCCAAGGCCCTGG
TCGCCTTCACCCAGAGCGGGGACACGGTCAAGCGCCTCTCCCGCTACCGCTCCCCGATCCCGCTCCTCGCCTTCACCCCG
GACGAGGCCACCCGCGCCCAGCTGAACCTCACGTGGGGCGTGGAGACGTTCCTGGGTCCGCACGTGGACTCGACGGACGC
GATGGTGGCGCAGGTGGACGAGGAACTGCTGCGGATCGGTCGCTGCAGGAAGGGGGACGTCGTGGTGATCACCGCGGGCT
CGCCTCCCGGGATCGCCGGCACGACGAACCTGGTGCGGGTGCACCACATCGGCGAGGACGACAGCCCGAAGTGA

Protein sequence :
MRRAKIVCTLGPATDTYDQIKALVEAGMDIARLNLSHGTYAEHEERYHHVRKASQETGRSVGILADLQGPKIRLGRFAEG
PVLLERGDTFTITTEPAEGDRHTCSTTYDGLAADVTAGERVLVDDGRVTLEVTGVDGPRVRTTVIEGGMVSDHKGLNLPG
VAVSVPALSEKDIDDLRWALRTGADVIALSFVRTGRDIEDVHRVMDEENRRLPVIAKVEKPQAVDNIDDIVAAFDGIMVA
RGDLGVEMPLEQVPIVQKRAVKLAKRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAIIDGTDAVMLSGETSVGKYPIE
TVATMARIVEAAEEDILAKGLPPLTDRNKPRTQGGAVARAAAEMGDFLGAKALVAFTQSGDTVKRLSRYRSPIPLLAFTP
DEATRAQLNLTWGVETFLGPHVDSTDAMVAQVDEELLRIGRCRKGDVVVITAGSPPGIAGTTNLVRVHHIGEDDSPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-82 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-82 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-82 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-82 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SACTE_1433 YP_004801890.1 pyruvate kinase VFG0479 Protein 8e-83 43