Gene Information

Name : SACTE_1392 (SACTE_1392)
Accession : YP_004801850.1
Strain : Streptomyces sp. SirexAA-E
Genome accession: NC_015953
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1555518 - 1557242 bp
Length : 1725 bp
Strand : -
Note : TIGRFAM: urease, alpha subunit; KEGG: sgr:SGR_846 urease subunit alpha; PFAM: amidohydrolase; Urease alpha-subunit domain protein

DNA sequence :
ATGCCCATCCTGCCGCGCAAGCAGTACACCGACATGTTCGGTCCGACGATCGGTGACCGCTTCTACCTGGGCGACACCAA
CCTCGTCGTCGAGGTCGAGAAGGACTACAGCGAAGGCCAGTACGGGGACGAGGTCCTCTACGGCGGTGGCAAGACCATGC
GTGACGGCATGGCCTCCGATCCGCAGGCCACCGCCGCCCAGGGTGCCCTCGACACCGTCATCACCAACGTGGTGGTCATC
GACCCCGTCGTCGGCGTCGTCAAGTGCGACATCGGCATCAAGGACGGCTTCATCGCCGGCATCGGCAAGTCGGGCAACCC
ACAGACCCAGGACCGGGTCGACGCAGGGCTGATCATCGGCCCCGGCACCGAGGCCATCGCGGGCGAGCACCTCATCGCCA
CGGCGGGCGCCATCGACACCCACGTCCACCTCATCGCGCCCCAGCAGGCCGAACAGGCCCTCACCAACGGCATCACCACC
CTCATCGGCGGCGGCACCGGCCCGTCCGACGGATCGAACGGCACCACGTGCACGCCCGGTCCGTACAACATCGGCCGGAT
CCTCCAGGCCGCGGAGAGCATCCCCGTCAACCTCGGGATCATGGGCAAGGGCAACGGCAGCCTGCCCGAGGCCCTCAACG
AGCAGGTCGCCGCGGGCGCCTGCGCCCTGAAGGTCCACGAGGACTGGGGGGCGACCCCGGCCGTGATCGACAACGCCCTG
AACGTCGCCGACGAGCACGACGTCCAGGTCGCGATCCACACCGACAGCCTCAACGAGAGCGGGTTCTTCGAGGACACCCG
CTCGGCGATCGACGGCCGCACCATCCACACCTTCCACAGCGAGGGCGCGGGCGGCGGTCACGCCCCCGACATCCTGCGCG
TGGCGGGCGAGCCGAACATCCTGCCGTCCTCGACCAACCCGACGCTGCCGTACACCAAGAACTCGGTGGACGAGCTGCTG
GACATGGTCATGGTCTGCCACCACCTCAGCCACGACATCCCCGAGGACGTCTCGTTCGCCGACAGCCGCGTCCGGGCCGA
GACGATCGCCGCCGAGACCGTCCTGCACGACCTCGGCGTGATCAGCATGTTCTCCTCCGACTCGCAGGCCATGGGCCGCG
TCGGGGAGTCCGTGACCCGCGCCTTCCAGACCGCCCACCACTGCAAGGACAAGCTGGGCGTGCTGGAGGGCGACTCGGAC
CGCAACGACAACCAGCGGGTCCTGCGCTACCTCGCCAAGGTGACCATCAACCCCGCCATCGCCACCGGCATCGCGGACCA
CATCGGCTCCATCGAGAAGGGCAAGCTCGCCGACATCGTGCTCTGGCCCATCCACTCCTTCGGCGCCAAGCCGAAGATGG
TCATCAAGGGCGGCATCATCTCCTGGGCGCAGATGGGCGACCCCAACGCCTCGCTCCCCACCCCGCAGCCGGTGACCTAC
CGCCCGATGTTCGGGCAGTACGGCAAGGCCCAGCAGGCCACCCACGTCACCTTCATGTCGCAGGCCGGCATCGCGGCCGG
CGTCCCGGCCGAACTCGGCCTGGAACGCACGGTCCTCCCGGTGCGCCGTACCCGGACCATCGGCAAGCACAACATGGTCC
GCAACGACGCGCTGCCGGAGATCAAGGTCGACCCGGAGACGTTCAAGGTCACCCTCAACGGCAAGGTCGCCACCATCGAC
CCGGCCGAGACCCTCCCCCTCAACCACCTGTTCTTCCTGGTCTAG

Protein sequence :
MPILPRKQYTDMFGPTIGDRFYLGDTNLVVEVEKDYSEGQYGDEVLYGGGKTMRDGMASDPQATAAQGALDTVITNVVVI
DPVVGVVKCDIGIKDGFIAGIGKSGNPQTQDRVDAGLIIGPGTEAIAGEHLIATAGAIDTHVHLIAPQQAEQALTNGITT
LIGGGTGPSDGSNGTTCTPGPYNIGRILQAAESIPVNLGIMGKGNGSLPEALNEQVAAGACALKVHEDWGATPAVIDNAL
NVADEHDVQVAIHTDSLNESGFFEDTRSAIDGRTIHTFHSEGAGGGHAPDILRVAGEPNILPSSTNPTLPYTKNSVDELL
DMVMVCHHLSHDIPEDVSFADSRVRAETIAAETVLHDLGVISMFSSDSQAMGRVGESVTRAFQTAHHCKDKLGVLEGDSD
RNDNQRVLRYLAKVTINPAIATGIADHIGSIEKGKLADIVLWPIHSFGAKPKMVIKGGIISWAQMGDPNASLPTPQPVTY
RPMFGQYGKAQQATHVTFMSQAGIAAGVPAELGLERTVLPVRRTRTIGKHNMVRNDALPEIKVDPETFKVTLNGKVATID
PAETLPLNHLFFLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 4e-137 59
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 4e-137 59
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-134 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-134 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-134 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-134 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SACTE_1392 YP_004801850.1 urease subunit alpha VFG0270 Protein 1e-134 56