Gene Information

Name : Calla_0654 (Calla_0654)
Accession : YP_004798283.1
Strain : Caldicellulosiruptor lactoaceticus 6A
Genome accession: NC_015949
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 714224 - 715975 bp
Length : 1752 bp
Strand : +
Note : KEGG: cki:Calkr_1247 pyruvate kinase; TIGRFAM: Pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region

DNA sequence :
TTGAGAAAAACAAAAATAATTTGTACATTGGGTCCAGCGACCGACTCAGAGGAGATAATAAGAAAGCTTGTTGAAAATGG
AATGGATGTTGTGAGATTAAATTTTTCTCATGGTACACATGAAGAGCATAAGAAAAAGATTGACATGGTAAAAAAGATAA
GAGAAGAACTTGACAAGCCTATTCCCATTTTGCTTGATACTAAAGGGCCAGAGATAAGAATAGGTTTTTTTAAGGACGGC
AAAGTAGAACTAAAAGAGGGTCAGAAGTTTGTACTGACTGTGGAAGAAATCTTAGGAAATGAAGAGATTGTGAGTATAAC
TTATAAAGAACTTATTGAGGATATAAAACCAGGTGATAAAATCCTGATAGATGATGGACTTATCGAGCTTATTGTTGAGG
ACAAGACAGAAAAGAACATAATCTGCAAGGTAAAAAATGGAGGAGTTTTGACCAACCAAAAAGGGGTAAATGTACCGGGC
ATACCCATAAGACTTCCTGCACTTACCCAGAAGGATAAAGAGGATATTCTGTTTGGGATAGAAAACGATGTAGATTTTAT
TGCAGCCTCATTTATAAGAAAGGCAAGTGACGTTGTTGAGATTAGAGAGTTTCTGAACAAAAATGGTGGAAAAGACATTT
TAATAATTGCTAAGATAGAAACTCAAGAAGGTGTTGCCAACTGCGACGAAATAATAAGGGTTGCAGATGGAATTATGGTT
GCAAGAGGAGATTTAGGGGTAGAACTTCCTTTTGAGGAAGTCCCCCTTGTTCAAAAAATGCTCATTGAAAAATGTTACAA
AGCAGGGAAGCCTGTCATAACAGCAACACAGATGCTTGAATCTATGATACGAAATCCAAGACCTACCAGGGCAGAGGTTA
GCGATATTGCCAATGCCATATTTGATGGCACTTCTGCAATAATGCTCTCTGGCGAGACGGCAATGGGCAAATACCCCGTT
GAAAGTGTTGCTACAATGGCAAAGATTGCCGAGAGAGTGGAAAATCAGATTGATTATATCAAGAGATTTCAGTCTCAGGT
ATTTGATATGCCTGTTAACGTTACAAATGCTATTTCGCACGCAACTTGTACAACCGCACATGACCTTGGCGCAAAGGCTA
TTATAACTGTGACAAAGTCAGGTAACACTGCAAGAATGGTGTCAAAATTCAGACCTGCTTGTCCGATTATTGCAACCACA
CCTTGTGAGAAGGTAAGGAGACAGTTGAATCTGTCATGGGGTGTGTATCCATTTTTGGCAGAGTACAAGACTTCAACCGA
TGATATATTTGACCAAGCTGTTGAGATAGCTGTGAAATCCAAGATTGTAAAAAATGGAGATTTAGTTGTCATTACCGCTG
GAGTTCCTGTTGGCGTGAGTGGAACAACAAATATACTTAAAGTTCATGTTGTAGGACATGTTCTGGTTGAAGGGCGTGGC
TGGGGAAGTGGAAAGGTGACAAGCAGGGTCTGTGTTGTAAAAACCATTAATGATCTTAAACAGAATTTTGAAGATGGAGA
TATTATTGTTACAAATCAAACAAATAACGAGTTTATACCATATATGAAAAGAGCATCTGGTATTATCACAGAAGAAGGTG
GACAGAACTCTCATGCAGTAATTGTAGGTGCTGCACTTGATATCCCTGTAATCACAGATGCTAAAAATGCATTAGAGATA
TTAAAAACAGGGATTGTGGTTACAATTGATACTCAAAAAGGCATTGTATTTAGTGGAGAGCAGAAGGTATAA

Protein sequence :
MRKTKIICTLGPATDSEEIIRKLVENGMDVVRLNFSHGTHEEHKKKIDMVKKIREELDKPIPILLDTKGPEIRIGFFKDG
KVELKEGQKFVLTVEEILGNEEIVSITYKELIEDIKPGDKILIDDGLIELIVEDKTEKNIICKVKNGGVLTNQKGVNVPG
IPIRLPALTQKDKEDILFGIENDVDFIAASFIRKASDVVEIREFLNKNGGKDILIIAKIETQEGVANCDEIIRVADGIMV
ARGDLGVELPFEEVPLVQKMLIEKCYKAGKPVITATQMLESMIRNPRPTRAEVSDIANAIFDGTSAIMLSGETAMGKYPV
ESVATMAKIAERVENQIDYIKRFQSQVFDMPVNVTNAISHATCTTAHDLGAKAIITVTKSGNTARMVSKFRPACPIIATT
PCEKVRRQLNLSWGVYPFLAEYKTSTDDIFDQAVEIAVKSKIVKNGDLVVITAGVPVGVSGTTNILKVHVVGHVLVEGRG
WGSGKVTSRVCVVKTINDLKQNFEDGDIIVTNQTNNEFIPYMKRASGIITEEGGQNSHAVIVGAALDIPVITDAKNALEI
LKTGIVVTIDTQKGIVFSGEQKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 9e-106 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-106 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-106 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-105 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Calla_0654 YP_004798283.1 pyruvate kinase VFG0479 Protein 2e-106 51