Gene Information

Name : BurJV3_2333 (BurJV3_2333)
Accession : YP_004792880.1
Strain : Stenotrophomonas maltophilia JV3
Genome accession: NC_015947
Putative virulence/resistance : Virulence
Product : (2,3-dihydroxybenzoyl)adenylate synthase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 2566544 - 2568196 bp
Length : 1653 bp
Strand : -
Note : KEGG: smt:Smal_2275 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase

DNA sequence :
ATGAACACGCCTACCGTTTCTTCCCGCCTGCCACTGCAGCAGGTGTGGCCTGATGACCTGATGGCGCGCTATCGCGAGGC
GGGCCACTGGCGCGGCGAGACCTTCCCGGCGTTCCTGCGCGAACGTGCGGAACGTTACGCGGATGACATCGCAGTCGTCG
CTGGCGATGTGCGCCTGAGCTATGCGCAGCTGTGGCACGAAGCCGGTCGCATCGGTGCCGGCCTGCTGGCGCTCGGCCTG
CAGCCCGGTGAGCGGGTGCTGGTACAGCTGGGCAACACCGCCGGATTCATCACCACCATCTGCGGGCTGTTCCGCGCCGG
CCTGGTGCCGGTGTACGCGCTGCCTGCACACCGCATCACCGAGCTGATGCACTTCGCCAACAAGGCCGAGGCCAGTGCCT
ACATCACTACCGACCTGCACGATGGCTTTGATCATCGCGGGCTGGCGCGGGCGCTGCAGGCCGAAGTGCCAGCCGTGCGC
CATGTGGTGATCGACGGCGATGCGGCGGAGTTCACCGCGCTGGAGGCGCTGCAGGGAGACCGCAGCCAGCTGCCGGCCGA
CCCGGATCCGCAGTCGGTGGCGTTCCTGCAGATTTCCGGAGGCAGCACCGGGTTGTCCAAGCTGATTCCGCGCACCCACG
ACGACTACATCTATTCGTTCCGTGCCAGCAATGACCTTTGCGGCATCGACCGCGACAGCGTCTACCTGGTCGCGCTGCCG
GCCGCGCACAATTTTCCGATGAGTTCGCCCGGCTTCTTCGGCGCGCTGTATGCCGGTGCGCGCGTAGTGCTCAGCCCCGG
CCCCGGCCCGGATGCGGCGTTCCCGTTGATCGCCCGCGAAAAAGTGACCTGCTGTGGCCTGGTGCCGCCGCTGGCGCTGT
TGTGGGCACAGGCCGCCGCTACCAGCAAGCACGACCTGTCCAGCCTGCAGGTGCTGCAGGTAGGCGGTGCCAAGCTGGTG
CCGGAAGCCGCACGGCGGGTGATCGACGGCCTGGGCTGCACCCTGCAGCAGGTGTTCGGCATGGCCGAGGGACTGGTCAA
CTACACGCGCCTGGATGATCCGGAGGAACTGATCGTGGCCTGCCAGGGCCGGCCGATCAGCCCGGACGACGAAGTGCGCG
TGGTCGATGACCATGACCAACCGGTAGCCGAAGGCGAAGTGGGGCATCTGCTCACCCGTGGCCCGTACACCATCCGTGGA
TACCACAACGATGCGGTGGCCAATGCACGTTCGTTCACCGACGACGGCTTCTATCGCACCGGCGACCGCGTGCAGCAGCT
GCCCGGTGGCTACCTGGTGGTGCAGGGCCGTGCCGGTGACCACATCAACCGAGCCGGTGAGAAGATTTCCGCCGAGGAGA
TCGAAGACCATCTGCTGGCGCACCCCGGCGTGTTCGACGCCGCCGTGGTCTCCATTCCCGATGAGTATCTCGGTGAGCGC
AGCTGCGCGTTCGTGATCCAGCAGGGTGAGCCGATCAAGGCGCCGGCACTGAAAGCCTGGATGCGTACGCGCGGCCTGGC
CGCCTTCAAGGTGCCGGACCAGGTCGTGTTCGTCGACAGTTTCGATACCACCGCGGTCGGCAAGATCAGCCGCCGCGAAC
TGCGCGCGCAGCTGCGCGCGCGTCATCTGCAACAGACAGGAGGAACGCGCTGA

Protein sequence :
MNTPTVSSRLPLQQVWPDDLMARYREAGHWRGETFPAFLRERAERYADDIAVVAGDVRLSYAQLWHEAGRIGAGLLALGL
QPGERVLVQLGNTAGFITTICGLFRAGLVPVYALPAHRITELMHFANKAEASAYITTDLHDGFDHRGLARALQAEVPAVR
HVVIDGDAAEFTALEALQGDRSQLPADPDPQSVAFLQISGGSTGLSKLIPRTHDDYIYSFRASNDLCGIDRDSVYLVALP
AAHNFPMSSPGFFGALYAGARVVLSPGPGPDAAFPLIAREKVTCCGLVPPLALLWAQAAATSKHDLSSLQVLQVGGAKLV
PEAARRVIDGLGCTLQQVFGMAEGLVNYTRLDDPEELIVACQGRPISPDDEVRVVDDHDQPVAEGEVGHLLTRGPYTIRG
YHNDAVANARSFTDDGFYRTGDRVQQLPGGYLVVQGRAGDHINRAGEKISAEEIEDHLLAHPGVFDAAVVSIPDEYLGER
SCAFVIQQGEPIKAPALKAWMRTRGLAAFKVPDQVVFVDSFDTTAVGKISRRELRAQLRARHLQQTGGTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-101 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-101 49
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-101 49
ybtE CAA21394.1 - Virulence HPI Protein 3e-101 49
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-100 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-101 49
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-100 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-101 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-101 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BurJV3_2333 YP_004792880.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0168 Protein 6e-112 51
BurJV3_2333 YP_004792880.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG1817 Protein 2e-106 48
BurJV3_2333 YP_004792880.1 (2,3-dihydroxybenzoyl)adenylate synthase VFG0932 Protein 5e-101 46