Gene Information

Name : Murru_3433 (Murru_3433)
Accession : YP_004789867.1
Strain : Muricauda ruestringensis DSM 13258
Genome accession: NC_015945
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 3798092 - 3800692 bp
Length : 2601 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB; COGs: COG0542 ATPase with chaperone activi

DNA sequence :
ATGAACTTTAATAATTTTACAATAAAATCACAAGAAGCCATTCAAAGGGCCCAGCAATTGGCCCAAGAATTTGGGCATCA
ACAAATCGAAAACGAACATTTGTTCAAGGCCATTGCCGAGGTCGATGAAAACGTGCTCCCCTTCATTTTGAAAAAACTGA
ATGTCAACACCAACCTCATCAATCAAATATTGGACAAGGAACTCCAAAGCTTTTCAAAAGTAACAGGAGGAGACATTATG
CTTTCCAGAGAGGCTGGAAAAACGGTGAACGAAGCCAATATCATCGCCAAAAGCCTTGGGGATGAATACGTTTCCGTTGA
GCACTTGTTATTGGCCATTTTCAAGTCCAAAAGTAAAATCGCTCAAATACTAAAAGATCAGGGCGTAACCGAAAAAGATT
TGAAAGCAGCCATTCAAGAACTGCGCAAAGGGGGCAAAGTCACTTCGCAAAGTGCCGAGGAAACCTATAACTCGCTGGAC
AAATACGCAAACAACCTCAACCAAATGGCCGATAGCGGTAAATTGGATCCTGTAATCGGTAGGGACGAGGAAATCCGTAG
GGTTTTGCAGATTTTGTCCAGACGTACCAAGAACAACCCGATGCTTGTGGGTGAACCCGGAGTGGGTAAAACCGCCATTG
CCGAAGGTTTGGCACACCGAATCATTCAAGGAGACATACCCGAAAACCTTAAGGACAAGGTCATCTATTCTTTGGATATG
GGAGCGCTCATTGCTGGAGCCAAATACAAAGGTGAGTTTGAGGAGCGTTTAAAAGCTGTGATCAAAGAGGTAACTTCATC
AGACGGGAACATTGTGCTCTTTATTGATGAAATCCACACTTTGGTAGGTGCAGGTGGCGGACAAGGCGCCATGGATGCCG
CAAACATCCTAAAACCTGCCTTGGCCCGTGGTGAACTTAGAGCTATCGGAGCAACTACATTGGACGAGTACCAAAAGTAT
TTCGAAAAAGACAAGGCCTTGGAGCGTAGGTTCCAAAAGGTCATAGTGGACGAACCCGATACCGAGAGCGCCATTTCCAT
CCTAAGGGGTATTAAGGAAAAATATGAGGCACACCATAAGGTTCGCATTAAGGATGATGCCGTAATTGGGGCCGTAGAGC
TATCCCAACGCTACATCACCAACAGATTTTTGCCCGATAAAGCCATTGACCTTATGGACGAAGCAGCTTCCAAACTTCGA
ATGGAAATCAACTCCAAACCTGAAGAATTGGATGTACTCGACCGTAAAATAATGCAGTTGGAGATTGAATTGGAGGCCAT
CAAAAGGGAAAACGACACTTCCAAGTTGAAAACGTTGAATTTGGATTTGGCCAACCTTAAAGAAGAACGAAATGAAATCT
TTGCCAAATGGGAAAGTGAGAAAACCGTGGTGGACAACATCCAAAAAACCAAAGAGGATATTGAAAACTACAAAGTAGAA
GCCGAACGTGCCGAACGAAACGGGGATTACGGAAAGGTAGCGGAATTGCGCTACGGTAAAATAAAAGAGTCCCAAGAAAG
ATTGGAAAAACTGCAAGATGAACTTGCTGAACAGCAAACCGCGGGCACTTTGATAAAAGAAGAAGTGACCTATGAGGATA
TTGCCGAGGTTGTGGCCAAATGGACAGGAATTCCCGTGAACAAGATGATGCAGAGTGAACGCGAAAAATTATTGCAACTG
GAAGACGTGCTGCACAAACGCGTGGTAGGCCAAGATGAGGCCATAATCGCCGTTTCCGATGCTATCCGAAGGAGTAGAGC
GGGCTTGCAGGACGCCAAGAAACCTATCGGTTCGTTCCTGTTCCTAGGTACTACAGGAGTTGGTAAAACCGAGTTGGCCA
AAACCTTGGCCGCCTATCTGTTCGATGATGAAAATTCCATCACACGGATAGATATGAGCGAATACCAAGAACGTCACTCC
GTGAGCCGTTTGGTAGGTGCGCCTCCAGGATATGTGGGTTATGATGAAGGCGGACAGTTGACCGAAGCGGTGCGTAGGAA
GCCCTATTCTGTCATCTTGTTGGATGAGATTGAAAAAGCACATCCGGATACCTTCAACATTCTATTGCAAGTGTTGGACG
AAGGTAGGCTGACCGACAACAAAGGTCGTGTGGCGGATTTCAAAAACTCCATCATTATTATGACCAGTAATATGGGCAGC
CACATTATTCAAGAGAAGTTTGAAGATGCCGTAGACTTGGAAAGCGCTTCGGAGTCAGCACGGATAGAAGTTTTGGGATT
GCTGCGTAAGACCATCAGACCCGAATTCTTGAACCGTATTGACGATATCATTATGTTTACTCCGTTGAGCAAATCGGACA
TCAAAGATATTGTAGGACTTCAATTGGACAACTTAAAGAAAATGTTGACCAAGCAAAACATCACCTTGGATGCCACCGAA
GAGGCAATAGACTATTTGGCAACAAAAGGTTTTGATCCACAATATGGTGCCCGACCTGTAAAAAGATTAATTCAGAAAGA
GGTTTTGAACAACCTTTCCAAAGAGTTGCTCTCAGGAAAAATAACTGCTGATAGCATCGTACTCTTAGACTCTTTTGATG
ATCAATTGGTATTTAGAAATCAAGATGAACTTGTAGAGTAA

Protein sequence :
MNFNNFTIKSQEAIQRAQQLAQEFGHQQIENEHLFKAIAEVDENVLPFILKKLNVNTNLINQILDKELQSFSKVTGGDIM
LSREAGKTVNEANIIAKSLGDEYVSVEHLLLAIFKSKSKIAQILKDQGVTEKDLKAAIQELRKGGKVTSQSAEETYNSLD
KYANNLNQMADSGKLDPVIGRDEEIRRVLQILSRRTKNNPMLVGEPGVGKTAIAEGLAHRIIQGDIPENLKDKVIYSLDM
GALIAGAKYKGEFEERLKAVIKEVTSSDGNIVLFIDEIHTLVGAGGGQGAMDAANILKPALARGELRAIGATTLDEYQKY
FEKDKALERRFQKVIVDEPDTESAISILRGIKEKYEAHHKVRIKDDAVIGAVELSQRYITNRFLPDKAIDLMDEAASKLR
MEINSKPEELDVLDRKIMQLEIELEAIKRENDTSKLKTLNLDLANLKEERNEIFAKWESEKTVVDNIQKTKEDIENYKVE
AERAERNGDYGKVAELRYGKIKESQERLEKLQDELAEQQTAGTLIKEEVTYEDIAEVVAKWTGIPVNKMMQSEREKLLQL
EDVLHKRVVGQDEAIIAVSDAIRRSRAGLQDAKKPIGSFLFLGTTGVGKTELAKTLAAYLFDDENSITRIDMSEYQERHS
VSRLVGAPPGYVGYDEGGQLTEAVRRKPYSVILLDEIEKAHPDTFNILLQVLDEGRLTDNKGRVADFKNSIIIMTSNMGS
HIIQEKFEDAVDLESASESARIEVLGLLRKTIRPEFLNRIDDIIMFTPLSKSDIKDIVGLQLDNLKKMLTKQNITLDATE
EAIDYLATKGFDPQYGARPVKRLIQKEVLNNLSKELLSGKITADSIVLLDSFDDQLVFRNQDELVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-104 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 5e-104 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Murru_3433 YP_004789867.1 ATP-dependent chaperone ClpB VFG2076 Protein 3e-131 44
Murru_3433 YP_004789867.1 ATP-dependent chaperone ClpB VFG2084 Protein 3e-109 41