Gene Information

Name : Murru_2450 (Murru_2450)
Accession : YP_004788910.1
Strain : Muricauda ruestringensis DSM 13258
Genome accession: NC_015945
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain-containing protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2706160 - 2708715 bp
Length : 2556 bp
Strand : -
Note : PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit

DNA sequence :
ATGGACGATAATTTTTCCCCCCGCGTAAAGGACGTTATAGCATACAGCAAGGAAGAAGCCCTGAGACTGGGCCATGATTT
TATTGGCACGGAACACCTTATGCTAGGTCTTTTAAGAGACGGAAATGGCAAAGCCATAAATATATTGGATGCACTCGATG
TGGATTTGGACCACCTGCGTAGAAAGGTGGAAATCCTGAGTCCCGCAAATCCGAATACAGGAACAATACAGAAGGACAAA
AAGAATCTTCATTTGACCCGCCAAGCAGAACGGGCCCTGAAGACTACTTTTTTGGAAGCAAAGCTCTTCCAAAGTTCTTC
CATCAACACAGCACATTTGCTGCTCTGTATTTTGAGGAACGAGAATGATCCAACAACTAAACTATTGCACAAACTGAAAG
TGGATTACGACAATGTCAAAGAACAGTTTAAATCCATGATCACTAGTGATGACGATTATATAGATACCCCGCAAGCGGAA
TCCTTCCCCGGGGACACAGATGATATGGGAGATAGCAAAGAAAGCTCTTTCGGTTCCAGTGCTTCCCAAAAAGGAAGCAA
AAAGTCCAAAACACCTGTTTTGGACAATTTTGGACGCGACCTGACCAAACTGGCCGAAGACAACAAATTGGACCCCGTAG
TGGGCAGAGAAAAGGAAATTGAGCGTGTTTCCCAAATATTGAGCCGTAGAAAAAAGAACAATCCACTGCTTATTGGTGAG
CCCGGTGTAGGTAAAAGTGCCATCGCCGAAGGATTGGCGCTGCGTATCATCAATAAGAAGGTATCACGTATTCTTTACAA
CAAACGCGTGGTAACCTTAGATTTGGCCTCTTTGGTCGCAGGTACAAAATACCGTGGCCAATTTGAGGAGCGGATGAAGG
CCGTAATGAACGAGTTGGAGAAGAATGACGATATCATCTTGTTCATTGATGAGATACACACTATTGTTGGTGCCGGTGGA
GCTACGGGCAGTTTGGATGCTTCCAATATGTTCAAACCTGCGCTGGCTAGAGGAGAAATTCAATGTATCGGTGCAACAAC
GCTTGATGAGTACAGACAATACATAGAAAAAGATGGTGCCTTGGAGCGTCGCTTCCAAAAGGTAATGGTAGAACCTACCA
CCGTGGAAGAAACCATCGAAATTTTAATGAACATCAAAGGAAAGTACGAAGAGCATCATAACGTAAACTATACCGACGAA
GCTATTTTAGCATGTGTAAAGTTGACCAACCGTTACATGACGGACCGCTTCCTTCCCGACAAGGCCATTGATGCACTGGA
CGAAGCAGGGTCTAGGGTACACATCGTCAACATGGACGTTCCCAAACAAATTTTGGAGCTGGAAAGCCAGCTGGAAGATG
TTCGAGAACTAAAGAACAGCGTTGTTAAAAAGCAGAAATACGAAGAGGCCGCCAAACTTAGGGACGACGAAAAACGTCTG
GAAAAGGATTTGGCATCCGCTCAAGAACGCTGGGAAGAAGAAAGCAAACTGCACAGGGAAACCGTTAGCGAAGATAATGT
TGCCGATGTAGTTTCCATGATGAGCGGCATTCCCGTAAACAGAATAGCACAGACCGAAAGCAATAAATTGGCCGAGCTGC
CAAACCTCATTAAAGGTTTTGTAATTGGTCAAGATGAAGCCGTGTCCAAAGTGGCAAGGGCCATACAACGAAACCGTGCC
GGACTCAAGGATCCAAACAAACCTATTGGTTCATTTATATTCTTGGGACAAACCGGAGTCGGTAAGACCCAATTGGCCAA
AATATTGGCTAAGGAACTTTTTGATTCCGAAGATGCCCTTATCCGCATAGATATGAGCGAATACATGGAAAAATTCGCCA
TTTCGAGATTGGTAGGTGCACCTCCCGGATATGTGGGTTATGAAGAAGGCGGGCAGTTGACCGAAAAAGTACGCCGTAAA
CCATATTCCGTAATATTGTTGGACGAAGTGGAAAAAGCGCATCCAGATGTATTCAATATGTTGTTACAGGTGCTGGATGA
TGGATTCCTTACCGATAGCCTTGGGCGTAAAATCGATTTTAGGAACACCATAATCATCATGACCTCCAATATCGGTGCAA
GACAATTGAAAGATTTTGGACAAGGCGTAGGTTTTGGTACGGCAGCCAAAAAAGCACAGGCCGATACACATCAAAAAAGT
GTCATCGAAAATGCATTGAAAAAGGCGTTTGCTCCAGAATTTTTAAACAGGATAGACGATGTAGTGGTATTCAATGCACT
GGAAAGAGAGGACATCCACAAAATCATCGATATCGAATTGAACAAATTGTACGAGAGGATCAAGGACATCGGGTACGACT
TAAATCTTTCTGATAAAGCAAAAGATTACATTGCCGATAAAGGTTTCGATAAGCAATATGGGGCACGACCTCTTAAAAGA
GCTATCCAAAAATATATAGAAGATACACTGGCCGAGGAAATCGTAAACTCCAAATTGGAAGAGGGCGACAGTATTTTTAT
GGACTTGGATGAGAAAAAAGAAGAACTCACCATCAAAATAAAAAAAGCTGAAAAATCACCCGAAGCTGAAAAGTAA

Protein sequence :
MDDNFSPRVKDVIAYSKEEALRLGHDFIGTEHLMLGLLRDGNGKAINILDALDVDLDHLRRKVEILSPANPNTGTIQKDK
KNLHLTRQAERALKTTFLEAKLFQSSSINTAHLLLCILRNENDPTTKLLHKLKVDYDNVKEQFKSMITSDDDYIDTPQAE
SFPGDTDDMGDSKESSFGSSASQKGSKKSKTPVLDNFGRDLTKLAEDNKLDPVVGREKEIERVSQILSRRKKNNPLLIGE
PGVGKSAIAEGLALRIINKKVSRILYNKRVVTLDLASLVAGTKYRGQFEERMKAVMNELEKNDDIILFIDEIHTIVGAGG
ATGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGALERRFQKVMVEPTTVEETIEILMNIKGKYEEHHNVNYTDE
AILACVKLTNRYMTDRFLPDKAIDALDEAGSRVHIVNMDVPKQILELESQLEDVRELKNSVVKKQKYEEAAKLRDDEKRL
EKDLASAQERWEEESKLHRETVSEDNVADVVSMMSGIPVNRIAQTESNKLAELPNLIKGFVIGQDEAVSKVARAIQRNRA
GLKDPNKPIGSFIFLGQTGVGKTQLAKILAKELFDSEDALIRIDMSEYMEKFAISRLVGAPPGYVGYEEGGQLTEKVRRK
PYSVILLDEVEKAHPDVFNMLLQVLDDGFLTDSLGRKIDFRNTIIIMTSNIGARQLKDFGQGVGFGTAAKKAQADTHQKS
VIENALKKAFAPEFLNRIDDVVVFNALEREDIHKIIDIELNKLYERIKDIGYDLNLSDKAKDYIADKGFDKQYGARPLKR
AIQKYIEDTLAEEIVNSKLEEGDSIFMDLDEKKEELTIKIKKAEKSPEAEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-180 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Murru_2450 YP_004788910.1 ATPase AAA-2 domain-containing protein VFG0080 Protein 8e-149 52
Murru_2450 YP_004788910.1 ATPase AAA-2 domain-containing protein VFG0079 Protein 0.0 50