Gene Information

Name : Murru_1128 (Murru_1128)
Accession : YP_004787594.1
Strain : Muricauda ruestringensis DSM 13258
Genome accession: NC_015945
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1241425 - 1242600 bp
Length : 1176 bp
Strand : -
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: fbc:FB2170_07025 Cys/Met metabolism PLP-dependent enzyme superfamily protein; PFAM: Cys/Met metabolism, pyridoxal

DNA sequence :
TTGTATGAAGATAGTTTTAGCATGAGCAAAAAAGAGTTAAAGTTTAACAGTAAGGCCATTCATGGTGGGCAGCACCCCGA
TAAAGCCTATGGTGCGGTAATGCCTCCCATTTACCAAACCTCTACTTATGCGCAATCCACTCCGGGAGGGCATAAGGGTT
ACGAATATTCCAGGGGGGCAAACCCTACCAGAACCGCTTTGGAAAATGCGGTGGCCAGTTTAGAGAACGGCAACTTTGGG
ATGGCTTTTGGCAGTGGCATGGCCGCCATAGATGCCGTGATGAAACTGTTGGGCCCTGGTGACGAGGTAATCTGTACAAG
TGACCTGTACGGAGGCAGCTATCGGCTTTTTAAGGGTGTTTTTGAAAAATTTGGGGTCAGGTTCAGGTTTTCAGATATGA
CGGATATGCAGGAACTGGCTTCACAAATCAATAGGAATACCAAGCTGGTGTGGGTGGAAACCCCTACCAACCCCATGATG
AATATTATTGACATTAAAGCCGTTTCAAAAATTGCAAAAGAGCATGAGTTGCTGTTGGCGGTGGACAATACGTTTGCCAC
ACCATACCTACAGCGACCGTTGGAGCTCGGTGCAGATATCGTGATGCATTCTGCTACTAAATACTTGGCCGGACATAGCG
ATGTGGTGGTCGGCGCCTTGGTGGTAAGGGATGAGAAATTGGCCGAGCAACTCTATTTTATCCAGAAATCCAGCGGAGGT
ATTTGCGGCCCTATGGATAGTTTTTTGACCCTTCGCGGCATTAAAACACTTCACGTGCGCATGCAACGACATTGCGAAAA
TGGGGAATCCATTGCTAAATATTTGGAGAATCACCCCAAAATCGATACCATATATTGGCCAGGGTTTGAATGGCATCCCA
ACCACGAGGTAGCCAAAAATCAAATGAGGGGCTTTGGCGGGATGATTTCCTTTGTGCCCAAAGGCGGAAGCTACGAAAGC
GCCATAAAAATTGTAGAGAAATTTCAACTATTCACACTAGCTGAATCGTTAGGAGGTGTCGAAAGTTTAGTGGGACATCC
GGCGAGTATGTCGCACGGTAGTATTCCAAAGGAAGAACGAGAAAAAAATGGTGTAGTTGATGCCCTGATCAGACTTAGCG
TGGGCATTGAGGATGTAGAAGATTTGATTGCAGATTTAGATCAGGCCTTGAAATAA

Protein sequence :
MYEDSFSMSKKELKFNSKAIHGGQHPDKAYGAVMPPIYQTSTYAQSTPGGHKGYEYSRGANPTRTALENAVASLENGNFG
MAFGSGMAAIDAVMKLLGPGDEVICTSDLYGGSYRLFKGVFEKFGVRFRFSDMTDMQELASQINRNTKLVWVETPTNPMM
NIIDIKAVSKIAKEHELLLAVDNTFATPYLQRPLELGADIVMHSATKYLAGHSDVVVGALVVRDEKLAEQLYFIQKSSGG
ICGPMDSFLTLRGIKTLHVRMQRHCENGESIAKYLENHPKIDTIYWPGFEWHPNHEVAKNQMRGFGGMISFVPKGGSYES
AIKIVEKFQLFTLAESLGGVESLVGHPASMSHGSIPKEEREKNGVVDALIRLSVGIEDVEDLIADLDQALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-89 53
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-90 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-65 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Murru_1128 YP_004787594.1 cystathionine gamma-synthase BAC0207 Protein 7e-76 45