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Name : Acife_2290 (Acife_2290) Accession : YP_004784727.1 Strain : Acidithiobacillus ferrivorans SS3 Genome accession: NC_015942 Putative virulence/resistance : Resistance Product : mercuric reductase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : - Position : 2268979 - 2270631 bp Length : 1653 bp Strand : - Note : KEGG: tbd:Tbd_1341 putative mercuric reductase; TIGRFAM: Mercuric reductase MerA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Heavy metal transport/detoxification protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation DNA sequence : ATGAATAAAGCGATGATGTTGGGCATTACGGGCATGACCTGTAATCATTGTGCTCAGATGGTGGAAAATGCGTTGCGCGC GGTTCCGGGCGTTGCATTGGCACAGGTGGCTTTTCCGAAAGAGCAGGCACAGATCGAAGTTTCCGAACCGGTATCCATGG AAGTGCTTGCTGCCGCCATCAACAAAGCGGGCTACGGTGTTTCGCTGCCTGAAAATGCCAGCACTCCGGTGGCAATGGCG GCAAAAAATGCCGATGCTACCGGCTTTCATGTCGCCATTATCGGTTCCGGATCAGGCGCCTTTGCTGCCGCCATCCGGGT GACGGAAGGGGGCGGACGGGTGACCATGATTGAATCCGGTACGTTGGGCGGCACCTGTGTCAATGTCGGCTGCGTGCCTT CCAAGATCATGATCCGTGCCGCGCAGATGGCCCAATGGCAGCGTGCCCATCCTTTTCGTGGTTTAAGTCATAGCGTATCC AGCGTGGATCGCGCCGCCCTGGTCGAGCAACAACAGGATCGTGTGGCTGAATTGCGTGAAGCCAAATATGCCCATGTGCT GGCTACGCATCCGGATATCACCTTTGTGCAGGGGCATGCCCGCTTTGCCGATGCCACAACCCTCGTGGTGCGCGCTGCCG ACGGATCGGAACAACGGATCCAGGCGGAGCGTTTTCTGATTGCGACGGGTGCCCATGCGCACTGCCCGGACATTGAGGGT CTGGCGCAAACACCTTACTGGACGTCAACGGAAGCCTTGGTAGCGCCCGAATTGCCGCGTCATCTCCTCATTCTGGGGGG GTCGGTTGTCGCGGTGGAGCTGGCGCAGGCCTTTCGCAGACTGGGCTGCGCAGTCACTCTGCTGGCGCGCAGCACACTCC TGTCCAAAGACGATCCGGCACTGGGTGCGGGGCTGGAGGCCGTATTTCAGGAAGAGGGAATTCGCGTGCTCAAGCACACC GTTCCCACGTCGGTGCATTACGAGAAGGACCGGTTTTTGATCAGCATAGGCGCTGAGACAATCCACGCGGATCGCTTGCT GGTGGCAACCGGGCGCACGCCCAATACGGCGGATCTGGGGCTGGAGCAGATCGGGGTAATCACCAACAAATCCGGGGCCA TTTCGGTGGATGCGCACATGCAAAGCAGTGTGCCCCACATTTATGCTGCCGGTGATTGCACGACCCATCCTCAGTTCGTT TACGTCGCCGCGGCGGGCGGCACCCGGGCGGCCATCAATCTGCTGGGCGGCGATGCCAGCCTGGATTTGCGGGTGCTTCC TGTCGTCGTATTTACCGATCCTCAAGTCGCTACAGTGGGGCTGGACGAGCGGACAGCGGCACAGCAGGAATTCACCACCG ACAGCCGCACACTGACCCTCGATAACGTACCCCGTGCACTGGCGAACTTTGATACACGGGGATTCATCAAACTGGTCGCG GACAAGCATAGCGGCAAACTGTTGGGTGCGCAGATTCTCGCCGCAGAAGGCGGAGAAATCATCCAGGCAGCCGCACTAGC CATACGTGGCGGTCTCGGCATTCAGGATCTCGCCGATCAGCTTTTCCCCTACCTGACCATGGTGGAGGGATTGAAACTCT GTGCCCAAACCTTCACCAAAGATGTCTCGCAATTATCCTGCTGCGCGGGATAA Protein sequence : MNKAMMLGITGMTCNHCAQMVENALRAVPGVALAQVAFPKEQAQIEVSEPVSMEVLAAAINKAGYGVSLPENASTPVAMA AKNADATGFHVAIIGSGSGAFAAAIRVTEGGGRVTMIESGTLGGTCVNVGCVPSKIMIRAAQMAQWQRAHPFRGLSHSVS SVDRAALVEQQQDRVAELREAKYAHVLATHPDITFVQGHARFADATTLVVRAADGSEQRIQAERFLIATGAHAHCPDIEG LAQTPYWTSTEALVAPELPRHLLILGGSVVAVELAQAFRRLGCAVTLLARSTLLSKDDPALGAGLEAVFQEEGIRVLKHT VPTSVHYEKDRFLISIGAETIHADRLLVATGRTPNTADLGLEQIGVITNKSGAISVDAHMQSSVPHIYAAGDCTTHPQFV YVAAAGGTRAAINLLGGDASLDLRVLPVVVFTDPQVATVGLDERTAAQQEFTTDSRTLTLDNVPRALANFDTRGFIKLVA DKHSGKLLGAQILAAEGGEIIQAAALAIRGGLGIQDLADQLFPYLTMVEGLKLCAQTFTKDVSQLSCCAG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 2e-130 | 57 |
| unnamed | ABR13401.1 | mercuric reductase | Not tested | PAGI-5 | Protein | 7e-120 | 55 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 1e-128 | 55 |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 1e-128 | 55 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 6e-128 | 55 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 4e-128 | 55 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 4e-128 | 55 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 1e-128 | 55 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 8e-124 | 54 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 8e-124 | 54 |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 1e-83 | 41 |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 2e-83 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Acife_2290 | YP_004784727.1 | mercuric reductase | BAC0653 | Protein | 3e-131 | 55 |
| Acife_2290 | YP_004784727.1 | mercuric reductase | BAC0652 | Protein | 3e-126 | 55 |
| Acife_2290 | YP_004784727.1 | mercuric reductase | BAC0650 | Protein | 2e-125 | 54 |
| Acife_2290 | YP_004784727.1 | mercuric reductase | BAC0651 | Protein | 8e-84 | 41 |
