Gene Information

Name : Acife_1705 (Acife_1705)
Accession : YP_004784164.1
Strain : Acidithiobacillus ferrivorans SS3
Genome accession: NC_015942
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1696793 - 1699393 bp
Length : 2601 bp
Strand : +
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase associated with various cellular activities, AAA-2; Clp, N-terminal; ATPase, AAA-type, core; Clp ATPase, C-terminal; KEGG: afr:AFE_1970 ClpB protein; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGCGTACCGATAAACTGACCACCAAATTTCAACAGGCGTTCCAGGATGCCCAGAGTCTCGCTCTAGGCCAGGATCATCA
GCAGATGGACCCCGTCCATCTGCTGATTGCTTTTCTTGATCAAGAAGGTGGCATCGCCCGGCCGCTCCTGTCAAAGGCCG
GCGTACGGGTCGATGCCCTGCGCAATCAGTTGAACCGCGTGCTGGAGTCCCTGCCGAAGGTACAAGGGCATCCGGGAGAG
GTGCAGGTGGGCCGCGATCTCACCAACATGCTCAACCTGGCCGACAAGATGGGCCAGAAACGCGGTGACACGTACATCTC
CACCGAACACTTCCTGCTGGCCTTGATGGATGACAAGGGTGAAGCCGGGCGCCTCCTGAAAGAGGCGGGCGCCACCATCA
AAGATCTGGAACAGGCCGTCCACGACCTGCACGGCGGGGAAAAAATCAATGATGTTAATGCTGAAGAGCAACGTCAGGCA
CTGGAGAAATACACCGTTGATTACACGGAGCGGGCCAGTCAGGGCAAACTGGACCCGGTGATTGGCCGTGACGACGAAAT
TCGCCGGACCATTCAGGTCTTGCTGCGGCGCAGCAAGAATAATCCGGTCTTGATCGGCGAGCCAGGGGTGGGCAAGACGG
CTATCGTCGAAGGACTGGCCCTACGCTTGATTAATGGCGAAGTGCCAGAATCCTTACGTGATAAACGCCTGTTGGGTTTG
GACTTGGGGGCGCTGATTGCCGGTGCCAAGTTCCGCGGCGAATTCGAGGAACGCCTGAAGTCCTTGCTCAATGACTTGGA
GAAGAGTGAAGGCAAAATTATTCTTTTCATTGATGAGATTCATATGCTGGTTGGGGCAGGAAAGGCTGAGGGCTCCATGG
ATGCGGGCAACATGCTCAAGCCAGCGCTGGCGCGCGGTGAATTGCATTGCATCGGTGCCACTACCTTGGATGAATACCGC
AAACATATCGAAAAGGATGCGGCTCTGGAGCGCCGTTTCCAACGCGTGCTGGTGGACGAGCCCAGTGTGGAAGATACCAT
CGCTATTTTGCGTGGTCTGAAAGAACGCTATGAAGCCCATCATGGCGTACGCATTACCGATCCGGCACTGGTCGCCGCAG
CGCAGCTTTCACATCGCTATATTACTGACCGTAACCTGCCCGACAAGGCCATAGATCTGATGGATGAAGCCGCCTCCCGC
ATTAAGATGGAGATCGATTCCAAACCTCAGGAACTGGATGAGCTGGAGCGCCGCATCATTCAATTGAATATTGAACGGGT
GGCGCTAGAGAAGGAAAAGGATGAAGCCAGCCGTAAGCGTCTGGGTATTCTACAAACTCAAATCAGTGAGTTAGGCCGCA
AATATCAGGAGTTGGAAGAAGTCTGGAAAGGCGAAAAGCTGGCGATTGAAGGTACCTCACAAATCCAAAAAGAACTGGAC
CGCAAGCGCGTCGAGCTGGATACGGCACGCCGTGCCAACGACTTAGAACGTATGGCGGAACTGCAATACAGCTCCATTCC
GGCACTGGAAGCGCAACTGCGCAATGCCGAAATCCATGCAGAATCTGCTGGTTCAGGTGCCAAACCCACCCTGCTGCGCA
CGGAAGTCGGCGAAGAGGAAATCGCCGAAGTGGTCGCCCGCTGGACCGGTATTCCTGTCTCGAAAATGCTGGAGGGCGAG
AAGGAAAAACTCCTGAAAATGGAAGAGCGTTTACAGGCGCGGGTGGTGGGCCAGAGCGAAGCCGTCGCGGCGGTATCCAA
CGCCATTCGCCGCTCCCGGGCAGGGCTGTCAGATCCCAGGCGTCCCAATGGTTCTTTCCTTTTCCTCGGCCCCACGGGTG
TTGGTAAAACGGAGTTGAGCAAGGCCTTAGCCGAGTTCCTTTTCGACAGTGAAGATCATCTGGTGCGGGTCGACATGAGT
GAGTTCATGGAGAAACATTCGGTGGCGCGCCTCATTGGAGCGCCTCCCGGATATGTGGGCTACGAAGAAGGCGGGTACCT
TACCGAAGCGGTGCGGCGCAAACCGTATTCCGTCATCTTGCTGGATGAGGTGGAGAAGGCCCACCCGGATGTCTTCAACA
TCCTTCTGCAGGTGCTCGATGATGGCCGTCTTACCGATGGCCAGGGGCGCACCGTGGATTTCCGCAACACGGTGATTGTC
ATGACCTCCAACCTGGGTTCCGACCGGATTCAGGAATTCGGTCGGAAGGGGGACTATGACGGCATGCGCGTTGCGGTAAT
GGATGTGGTGCAGGATCATTTCCGCCCGGAGTTTCTCAATCGCATTGATGAGTTGGTCATCTTCCATCCGCTCACCGCAG
TGCAACTCCGCGAGATTACTGAGATTCAGATGGGCTTCCTACGGGCACGCCTGCGCGAACGGGATATGGGACTGGTGCTC
AGTGATGGCGCACTGGATCGTTTGGCCGAGGTCGGCTATGACCCCGCCTATGGCGCACGTCCCCTCAAAAGGGTGATTCA
GCGGGAAATCGAAAACCCCCTCGCACAGCAATTACTGCGGGGTGATTTCGGACCTGGTGAGATTATTGAAGTGCTTCTTG
AAGGCGACAGCTTTACCTTTGCCGGACGGCGCCCGCACTGA

Protein sequence :
MRTDKLTTKFQQAFQDAQSLALGQDHQQMDPVHLLIAFLDQEGGIARPLLSKAGVRVDALRNQLNRVLESLPKVQGHPGE
VQVGRDLTNMLNLADKMGQKRGDTYISTEHFLLALMDDKGEAGRLLKEAGATIKDLEQAVHDLHGGEKINDVNAEEQRQA
LEKYTVDYTERASQGKLDPVIGRDDEIRRTIQVLLRRSKNNPVLIGEPGVGKTAIVEGLALRLINGEVPESLRDKRLLGL
DLGALIAGAKFRGEFEERLKSLLNDLEKSEGKIILFIDEIHMLVGAGKAEGSMDAGNMLKPALARGELHCIGATTLDEYR
KHIEKDAALERRFQRVLVDEPSVEDTIAILRGLKERYEAHHGVRITDPALVAAAQLSHRYITDRNLPDKAIDLMDEAASR
IKMEIDSKPQELDELERRIIQLNIERVALEKEKDEASRKRLGILQTQISELGRKYQELEEVWKGEKLAIEGTSQIQKELD
RKRVELDTARRANDLERMAELQYSSIPALEAQLRNAEIHAESAGSGAKPTLLRTEVGEEEIAEVVARWTGIPVSKMLEGE
KEKLLKMEERLQARVVGQSEAVAAVSNAIRRSRAGLSDPRRPNGSFLFLGPTGVGKTELSKALAEFLFDSEDHLVRVDMS
EFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVIV
MTSNLGSDRIQEFGRKGDYDGMRVAVMDVVQDHFRPEFLNRIDELVIFHPLTAVQLREITEIQMGFLRARLRERDMGLVL
SDGALDRLAEVGYDPAYGARPLKRVIQREIENPLAQQLLRGDFGPGEIIEVLLEGDSFTFAGRRPH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-93 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-92 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 7e-93 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Acife_1705 YP_004784164.1 ATP-dependent chaperone ClpB VFG2076 Protein 2e-98 42