Gene Information

Name : Cycma_4530 (Cycma_4530)
Accession : YP_004776453.1
Strain : Cyclobacterium marinum DSM 745
Genome accession: NC_015914
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 5491512 - 5493164 bp
Length : 1653 bp
Strand : +
Note : PFAM: Pyridine nucleotide-disulphide oxidoreductase; Heavy-metal-associated domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: mercuric reductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoami

DNA sequence :
ATGAACGAAGAAAACATAAAACTGGATATCACAGGCATGACCTGCGACCAATGTGCCACAAGCATTGAAAAGCTACTTGC
TGAAAACAAAGGGGTACAAGAAGCCAAAGTAAGCTATTCTAAAGCTACTTGTGAATGCTCTTTTGATCCTTCAAAAACGA
CTAAGGAAAAAATAATCAATATCATCAACAGTACTAAAAACTACGGAGTAAAAGTTGAAATACTAGAAAATGAAAATAGT
AGTTACACCCAATTTGACCTCATAATAATCGGTGGTGGCTCGGCAGCCTTTTCAGCTGCTATAAAAGCTGAAAGTTTAGG
ACTTTCAACCTTAATGGTAAATGACGGTTTGGACTTTGGAGGTACTTGCGTAAATGTGGGCTGTGTGCCTTCCAAAAATC
TAATTCGTGCAGGCGAAACGGCTTATCATGCTACTCATTCTAACTTTGAAGGCATTCGGCCGAAAGGAGTGAATATTGAT
TTTGCTCAAGTCATCAAGGACAAGAAAAAAATGGTTGCTACACTGCAAGAGAAAAAATATTTGGATGTGGTGAGCGATTT
TAAAAACCTGACCATGTTAAAAGGTTGGGCAAGGTTCATAGACAACCAAACAATTGAAGTGGATGGGGAAAGGTACAAAG
CAATCAAATTTTTAATTGCCACAGGCGCTACTACCAACATTCCTAATATTGAAGGATTGGACAAAATCGACTATTTGACC
AATGTTTCCCTTTTTGACTTGGAAGAGAAACCAGTAAGTCTGACCATCATGGGAGCAGGTTATATCGGTTTGGAAATTGC
AATGGCTTACAATCGATTAGGGGTAAAAGTTCGTGTCATAGAATTCACCGACAGAGTATTGCGAACACAAACACCAGACA
TCAGCGAAGCATTGGAAAGCCAAATGCGAAAAGAAGGCATTGAAATGTTACCCAATTTCAGAGCGGTAAAGTTTGAAAAA
CAAGGCAACGTAACCACAATACATTGCAAATGTCCTGACGGTTCATTCACTAAATTTGTTGAAAAAGGAAAGGTAGTAAT
TGCAACAGGAACCAACCCCCATTCAAGCCAATTAGGGTTAGACAATATTGGTTTGGACCTCACCAAACATGGACATATCG
CAGTAAATGAAAAAATGGAAACCAATCTATCCAACATCTATGCAGCAGGAGACGTAGCCAATACGCCCACATTTGTTTAT
ACCGCTGCCTTTGAAGGAAAAATTGCCGTTGAAAACGCTTTCACAGGAACAGAGAATAAAGCAGATTATTCTTCCTTGCC
ATGGGTGGTATTTACCGATCCACAGGTGGCAGGTGCGGGTATGGACGAAGCTCAGGCCAAAGCGAACGGTATTCCATTTG
AAGTTTCTAAATTGGAACTCAAAGACGTACCAAGAGCAATAGCAGCGAATGACACTAGGGGATTTATCAAACTCATTCGC
AACAGCGAAACTGATAAATTGATTGGGGCAAGAATAGTCGCTCCCGAAGGCGGAGAATTGATTCAACAATTGAGTATGGC
AATCAAATACGGAATTACCGTGAAAGATTTGGCAGACAGTTTTTACCCTTACCTGACTTTGGGAGAAGGTATCAAATTAG
CAGCAATAACTTTTGGAAAAGACGTATCTAAATTAAGTTGCTGTACCAGTTAG

Protein sequence :
MNEENIKLDITGMTCDQCATSIEKLLAENKGVQEAKVSYSKATCECSFDPSKTTKEKIINIINSTKNYGVKVEILENENS
SYTQFDLIIIGGGSAAFSAAIKAESLGLSTLMVNDGLDFGGTCVNVGCVPSKNLIRAGETAYHATHSNFEGIRPKGVNID
FAQVIKDKKKMVATLQEKKYLDVVSDFKNLTMLKGWARFIDNQTIEVDGERYKAIKFLIATGATTNIPNIEGLDKIDYLT
NVSLFDLEEKPVSLTIMGAGYIGLEIAMAYNRLGVKVRVIEFTDRVLRTQTPDISEALESQMRKEGIEMLPNFRAVKFEK
QGNVTTIHCKCPDGSFTKFVEKGKVVIATGTNPHSSQLGLDNIGLDLTKHGHIAVNEKMETNLSNIYAAGDVANTPTFVY
TAAFEGKIAVENAFTGTENKADYSSLPWVVFTDPQVAGAGMDEAQAKANGIPFEVSKLELKDVPRAIAANDTRGFIKLIR
NSETDKLIGARIVAPEGGELIQQLSMAIKYGITVKDLADSFYPYLTLGEGIKLAAITFGKDVSKLSCCTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 3e-68 41
merA AGK07021.1 MerA Not tested SGI1 Protein 3e-68 41
merA AGK07079.1 MerA Not tested SGI1 Protein 3e-68 41
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 7e-68 41
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 5e-68 41
merA AFG30120.1 MerA Not tested PAGI-2 Protein 5e-68 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cycma_4530 YP_004776453.1 mercuric reductase BAC0649 Protein 3e-177 71