Gene Information

Name : Cycma_4506 (Cycma_4506)
Accession : YP_004776433.1
Strain : Cyclobacterium marinum DSM 745
Genome accession: NC_015914
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 5470926 - 5473439 bp
Length : 2514 bp
Strand : -
Note : PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase; InterProIPR006404:IPR006416:IPR001757:IPR00825

DNA sequence :
ATGAAAAAGCTACAAATAAAAATACCATTACTCCTGCCTGAAGTACCGGACGAGAAGGATCAATGTGTGCAAAAACTTAT
TCAACAACTTCAGGATAAAGAAGGCCTTGAAAAAGTGCATGTAGCAGACGAAACCGACAATGGCGTACCACAGCTATGCT
TTCACTATAACCCTGAGCTTATTACGATTGATCAGATACAAAAATTAGCTAAACGTACAGGTGCTTCCATTATTGATAAA
TACGGTCACCGGTTAATTGAGGTAGAAGGGATTCGTCATACCCGTCATGCCAGAAAAATTGAAGAAGCACTCAATAGATT
AGATGGAGTTTTACAGTCCGCAGTATCTGCTTCGGGTATGATCGGATTAGAATTTGAAACAGCAAAAATAAACGATGAAA
AAATCCTTACTGTATTGCGCAAAGAAGGTTTAGATATTCTATCTACAGAAGTAGAAGTCGAGCGGTACATAAAAAAGACA
CATGAAGCCGAAAAAGGCGAAGAGCAAAAAGAAGAAGCTGATAAGGAACATGAACATGAGGAAGGTGAAGATCATGAACA
TTCGCATGGAGGCATTTTCGGTAAAAACACCGAGCTGATTTTTTCTATCATCTGCGGAGCATTGCTCGGAATTGGCTTTG
GATTGTCTTATGTAGAGGCTGTGCCTTCCTGGGTGAGCCTCGCATTATACATCGGGGCATACTTCTTTGGTGGCTATTTC
ACAGCCAAAGAAGCCATTCAAACAGTGGCCAAAGGCGGCTTTGAAATTGATTTCCTGATGCTGGTAGCGGCCATTGGAGC
GGCAATTCTGGGCGAATGGGCGGAAGGTGCATTACTCCTCTTCCTTTTTAGCATGGGGCATGCGCTGGAACACTATGCCA
TGAACAAAGCCCGTAAATCCATTGCTGCTTTAGCAGATCTCGCTCCTAAAACGGCATTAGTTAAGCGAAATGGTAAAACG
GAAGAAGTAGGTATAGAAGAACTAAGCATAGGCGACATCATTGTGGTGAAGCCCAATAGCAAAATCTCAGCCGATGGCGT
GATTGTCAGTGGTACAAGTAGTGTGAATCAGGCACCAATCACCGGGGAAAGTGTGCCGGTAGATAAAGAACCGGTGGATA
ATCCCGATAAAGACTGGTCACAGGAAAAAGACATCAAAGACGAGAACCGTGCTTTTTCGGGTACCATCAATGGCAACAAT
ACGCTGGAAATCAAAGTCATTAAAGTAGCGAAGGACTCTACCCTCTCCCGTTTGGTAAAATTGGTGAATGAAGCCCAGAC
TCAGAAATCACCTACCCAACTTCTTACTGATAAGTTTGAGAAATACTTCGTGCCTTCTGTACTGGCACTGGTTGTACTAT
TGCTAGGTGCTTTTTTGGTCATTGACGAAACCTTTAGTGAGAGTTTTTACCGCGCGATGGCCGTACTGGTTGCTGCAAGT
CCATGTGCGTTGGCGATCTCCACGCCTAGCGCTGTTTTGAGTGGGGTTGCCCGCGCTGCAAAAGGTGGTGTGCTTATAAA
AGGTGGACGGCCGTTGGAAGATCTGGGCGTTTTGACAGCTCTGGCCTTCGACAAAACCGGAACGCTAACCGAGGGAAAAC
CTAAACTCACCAAAGTAGTTCCTCTTGGGAACGTGAGTGAAAATGAACTCTTAAAAATAGCGGTGGCGGTGGAAAACCTA
AGTGACCACCCGCTGGCAAAAGCGGTAGTGAGGGATGGGAAAGAGCGGTTAAAAGATACAGTCATTCCAGAAGCGAGTGA
TCTTGAAGCCGTGTTGGGGAAAGGGATCAAAGCTTCATTGGGAAGTGATAAAATCTACATAGGAAACCTTGACTTGTTTG
AGGATCTGGATGAAAATAAACCTTCTCAGGAAATAGAAGAACAAGTAAGGGAACTCGAAGGAGGTGGCAACACCACCATG
CTTATCCGCAGGAACGCAGAATACATCGGTACGATAGCACTAATGGACACACCGCGTGAATCGGCAAAGGCAACTCTGGC
CGAACTGAAAAAAATTGGCATCAAGCGCATGATCATGCTTACCGGGGATAACCAGCAAGTAGCCGATGCTGTAGCCAAAG
AAATCGGGCTTACAGATGCCTGGGGAAGCTTGTTGCCCGAAGAAAAAGTGGATGCTATCAAAAAATTGAAAGAACAAGAA
TCTAAAGTAGCGATGGTTGGTGATGGCGTGAATGATGCCCCAGCCATGGCCAACAGCACGGTAGGTATTGCTATGGGAGC
TGCCGGAAGTGATGTAGCTCTGGAGACAGCCGATATCGCCTTGATGGCGGACAAGCTGGAAACTTTGCCTTTTGCAATTG
GGTTGAGTAGAAAGGCAAAAGGCATTATCAAGCAAAATCTCTGGATTAGTTTAGGAATAGTGGCTTTGCTAATTCCTTCA
ACTATTTTTGGTTTGGCTAATATTGGTATTGCAGTGCTTATTCATGAAGGTTCTACCTTGGTGGTAGTCTTTAATGCATT
GAGATTATTGGCATATAAAAAACACCTATCTTGA

Protein sequence :
MKKLQIKIPLLLPEVPDEKDQCVQKLIQQLQDKEGLEKVHVADETDNGVPQLCFHYNPELITIDQIQKLAKRTGASIIDK
YGHRLIEVEGIRHTRHARKIEEALNRLDGVLQSAVSASGMIGLEFETAKINDEKILTVLRKEGLDILSTEVEVERYIKKT
HEAEKGEEQKEEADKEHEHEEGEDHEHSHGGIFGKNTELIFSIICGALLGIGFGLSYVEAVPSWVSLALYIGAYFFGGYF
TAKEAIQTVAKGGFEIDFLMLVAAIGAAILGEWAEGALLLFLFSMGHALEHYAMNKARKSIAALADLAPKTALVKRNGKT
EEVGIEELSIGDIIVVKPNSKISADGVIVSGTSSVNQAPITGESVPVDKEPVDNPDKDWSQEKDIKDENRAFSGTINGNN
TLEIKVIKVAKDSTLSRLVKLVNEAQTQKSPTQLLTDKFEKYFVPSVLALVVLLLGAFLVIDETFSESFYRAMAVLVAAS
PCALAISTPSAVLSGVARAAKGGVLIKGGRPLEDLGVLTALAFDKTGTLTEGKPKLTKVVPLGNVSENELLKIAVAVENL
SDHPLAKAVVRDGKERLKDTVIPEASDLEAVLGKGIKASLGSDKIYIGNLDLFEDLDENKPSQEIEEQVRELEGGGNTTM
LIRRNAEYIGTIALMDTPRESAKATLAELKKIGIKRMIMLTGDNQQVADAVAKEIGLTDAWGSLLPEEKVDAIKKLKEQE
SKVAMVGDGVNDAPAMANSTVGIAMGAAGSDVALETADIALMADKLETLPFAIGLSRKAKGIIKQNLWISLGIVALLIPS
TIFGLANIGIAVLIHEGSTLVVVFNALRLLAYKKHLS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 4e-111 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-115 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 7e-115 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cycma_4506 YP_004776433.1 heavy metal translocating P-type ATPase BAC0124 Protein 0.0 55