Gene Information

Name : Cycma_3301 (Cycma_3301)
Accession : YP_004775256.1
Strain : Cyclobacterium marinum DSM 745
Genome accession: NC_015914
Putative virulence/resistance : Unknown
Product : type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 3871815 - 3873383 bp
Length : 1569 bp
Strand : +
Note : PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM); COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356:IPR004546; KEGG: sua:Saut_1346 type I restrict

DNA sequence :
ATGTCAGAAGACCAAAAGAAAGTTCTTGAAAGCCAATTATGGGGCATTGCCAACTTGCTTAGAGGTAAAATTAGTGCCGA
TGATTACAGAGACTATATTCTTGGCTTTATCTTTTATAAGTACCTTTCTGAGAAGCAAGCACTTTACGCCAATGAATTGC
TTGTTGGTGAAAAAGTAACGGATTACAAAAAAGTAACAGACCAGGAAACTTTAACTGCAATCAAAGAAGAGTCTTTATTG
AAATTGGGCTATTTTTTAGAGCCTGCACAATTGTTTTCTGTGCTAGCAGCAAAAGGGAATGCCGATACAGAAAGTGAAAG
CAACTACATTTTAGAAGATTTGCAATCTGTACTGAATCATATTGAGCAAAGTACCATGGGTACGGAGTCCGAAGAGGATT
TTAATGCCTTGTTTGAGGACTTGGATTTGAACTCTACCAAAATAGGCAGAACAGTTGGTGCTAGGAATGAAATCATTGTA
AAGGTATTGATGTATTTAGACAAGATTGATTTCAAACTGGAAGATCTTGATGCAGACGTTTTGGGGGATGCCTATGAGTA
TTTGATTGCCAAGTTTGCAGCAGGTGCAGGAAAATCTGCCGGGGAGTTTTATACACCTCAACAGGTTTCTAAAATACTTG
CCAAGATTGTTACAACAGGTAAATCGAAAATCAAATCAGTATACGATCCAACATGTGGTTCTGGTTCATTGCTCTTGCGA
GTAGCCAAAGAAGCGTCTGTAAGTGAGTTTTACGGTCAAGAACTAAACCGTACCACCTTCAATTTGGCACGTATGAACAT
GATTTTGCATGATGTACATTTCAGTGATTTCAATATCATGCAGGAAGACACGCTGGAAAACCCACAGCATTTGGACAAAC
GCTTTGAAGCGGTGGTGGCTAATCCACCATTTTCTGCGCATTGGAAAAGCAATGACAATCCCCTGTTCAATACAGATGAA
CGCTTTAGTCAGTATGGACGCTTGGCACCAAAGACCAAGGCCGATTACGCTTTCTTAACCCACATGCTGTATCAGTTGGC
CGACAATGGCATTATGGCAAGCGTTTTTCCGCATGGCGTTTTGTTTAGAGGAGCTGCAGAAGGTCACATCCGGGAATACA
TCATTAAAGAAATGAATGCCTTGGATGCTGTGATTGGACTACCGGCCAATATCTTCTATGGAACATCTATTCCTACCTGT
ATTCTCGTGCTAAAAAAATGCCGTGAGGTAGATGACAATATTGTATTTATTGATGCCAGCGGAGACGACCATTTTGTAAA
AGAAGGCAACCAAAATGTATTGCGTAATGAAGATGTAGAACAAATTGTAAACACCTATCGCAACCGTGAAACTATAGATA
AATACAGCTATGTAGCCACGCTTGACGAAATTGCCGAAAACGACTACAATTTAAATATACCACGTTATGTCGATACTTTT
GAAGAGGAAGAGCCGGTGGATTTGGATACTGTTTCTGCTGAACTCAAGCAAATACAAATCGATTTGCAAAGCACCAACGA
GACTATTGCAGGATTTTGTGCGGAACTTAATATTTTAACTCCTTTTTAA

Protein sequence :
MSEDQKKVLESQLWGIANLLRGKISADDYRDYILGFIFYKYLSEKQALYANELLVGEKVTDYKKVTDQETLTAIKEESLL
KLGYFLEPAQLFSVLAAKGNADTESESNYILEDLQSVLNHIEQSTMGTESEEDFNALFEDLDLNSTKIGRTVGARNEIIV
KVLMYLDKIDFKLEDLDADVLGDAYEYLIAKFAAGAGKSAGEFYTPQQVSKILAKIVTTGKSKIKSVYDPTCGSGSLLLR
VAKEASVSEFYGQELNRTTFNLARMNMILHDVHFSDFNIMQEDTLENPQHLDKRFEAVVANPPFSAHWKSNDNPLFNTDE
RFSQYGRLAPKTKADYAFLTHMLYQLADNGIMASVFPHGVLFRGAAEGHIREYIIKEMNALDAVIGLPANIFYGTSIPTC
ILVLKKCREVDDNIVFIDASGDDHFVKEGNQNVLRNEDVEQIVNTYRNRETIDKYSYVATLDEIAENDYNLNIPRYVDTF
EEEEPVDLDTVSAELKQIQIDLQSTNETIAGFCAELNILTPF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 4e-137 57
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 1e-136 57
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 4e-137 57
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 4e-137 57
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 3e-137 57
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 5e-137 57
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 5e-137 57
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 3e-135 57
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 9e-137 57
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 7e-137 57
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 7e-137 57
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 1e-136 56
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 2e-135 56
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 9e-137 56
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 4e-136 56
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 4e-136 56
ORF6 BAC22943.1 - Not tested etd PI Protein 3e-136 56
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 1e-136 56
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 1e-136 56
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 1e-136 56
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 1e-136 56
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 5e-135 56