Gene Information

Name : Cycma_2517 (Cycma_2517)
Accession : YP_004774487.1
Strain : Cyclobacterium marinum DSM 745
Genome accession: NC_015914
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2942796 - 2945411 bp
Length : 2616 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB; COGs: COG0542 ATPase with chaperone activity ATP-

DNA sequence :
ATGGATTTCAAGCAATTTACAATTAAATCACAAGAGGTGATTCAGAAAGCCTTGGAGCTATGTACCGCTGAGCAACAGCA
GCTAATAGAGCCTGCTCACTTGCTGAAAGGAATTGTCCAAGTAGATGCCAATGTTACGGATTTTATATTTCAGAAATTAG
GGATCAATTCAGGGTTGATCTTACAGAAGTTAGATGAAATCATTAACCAATATCCAAAGGTAAGTGGCCAGCAACCCTAT
TTATCCAACGCAACCAATGAGGTGCTAACACAAGCTAAAAAGTACCTGAAGACTTTTGGGGATGAATTTGTAGCAGTAGA
GCATTTGTTATTAGGTGTTTTGGCCGGTTCCGAGAAAGTAGCCCAGCTATTAAAAGGACAAGGCTTGAATGAAAAGAAAT
TAATAGAAGTAATAAAGGAACTTAGAAAAGGAAATAAAGTGACAGATCAAAATGCAGAATCTAAATACAGGTCTTTAGAA
AAATATTCTAAGAATTTAAATGACCTGGCCAAAAAAGGAAAAATTGATCCTGTCATCGGTAGGGATGAAGAAATCAGGAG
GGTCTTACAAATTTTGGCAAGAAGGACCAAAAATAATCCTATTTTATTGGGAGAACCGGGGGTAGGAAAAACTGCCATTG
TAGAAGGTTTGGCCCAAAGAATTGTAAGTGGAGATGTTCCTGAAAACCTTAAAAGCAAAACCCTTATTTCATTAGATATG
GGGCTTTTGGTGGCAGGGGCTAAATACAAAGGAGAATTTGAAGAGCGTCTAAAAGCAGTCATTAAGGAAGTAACGGACTC
TGACGGTGAAATTATCTTATTTATTGATGAGATCCATACCTTGATAGGGGCCGGAGGTGGAGGAGAAGGTGCAATGGATG
CGGCTAATTTATTGAAACCGGCCCTGGCTAGAGGAGAGCTACATGCCATTGGTGCAACAACTTTGAAAGAATACCAGAAG
TACATTGAAAAGGATAAAGCACTTGAGCGTCGTTTCCAGCAAGTGGTGGTAGATGAGCCGGATGCTGCAGATGCCATTTC
CATTTTAAGAGGTATAAAGGACAAGTATGAATTGCACCATGGTGTAAGGATCAAAGATGATGCAGTTATTGCCGCAGTAG
AGCTTTCACAACGCTATATATCGGATCGTTATTTGCCCGATAAGGCCATCGATTTAATGGATGAAGCAGCGGCCAAATTA
AGGATGGAAATTGACTCTCTTCCTCAAGAATTGGATGAGCTGAACAGACGTATAATGCAGCTGGAAATAGAAAGGGAGGC
CATTAGGCGTGAAAAAAATAAGGACAAGGAGAGTGTTCTAAGTAAAGAACTTGCAGACCTATCTGAAAAGAGGCAAGAAC
TGAAGGCGAAATGGGAAGGTGAAAAAGCCGTAATTCAGGGCATTCAAAGGGAAAAAGAGAACATTGACAAATTTAAAATA
GAAGCTGAACAGGCGGAACGAAGTGGTGACTTTGGAAAGGTTGCTGAGATCCGCTATGGGAAAATTGTGGATAGTGAGCA
AAAGCTGGAATCTTTTAAAGAACAGCTGAAGGTGATGCAAGAAAATTCCACCTTGCTTAAAGAGGAGGTAGATAGTGAAG
ACATTGCGGCTGTGGTCAGTAAGTGGACAGGTATCCCTTTGTCCAAAATGATCCAAAGTGAAAGAGAGAAATTGCTTCAT
TTGGAAGAGGAATTAGGCAAGCGCGTGGCTGGTCAGAAGGAAGCTATTACTGCGCTTTCGGATGCAGTAAGAAGAAGCAG
GGCAGGTTTGCAGGATCCGAAGCGACCTATAGGTTCATTTATATTCTTAGGTACTACAGGAGTTGGTAAAACAGAATTAG
CCAAAGCACTGGCAGAATACCTGTTTAGCGATGAGAATGCAATGGTAAGGATCGACATGTCTGAATATCAAGAAAGGCAT
GCAGTAAGCAGATTGGTTGGAGCACCTCCAGGGTATGTAGGCTATGATGAAGGTGGTCAACTAACAGAAGCAGTAAGAAG
GAAGCCTTACTCCGTGGTATTGCTTGATGAAATTGAAAAGGCTCACCCGGATGTGTTCAATATTCTCCTTCAAGTTTTAG
ATGATGGTAGGCTTACCGACAATAAAGGAAGGATAGCCAATTTCAAGAACACAATTATTATCATGACCACAAATATTGGA
TCTCATTTAATTCAGGAACGGTTTGAGAGCCTCAACGAGAGCAATAAGGAAGCAGTGCTGGAAAGTACAAAAGAAGAGGT
TTTCAATTTATTGAAAAAATCTGTGCGTCCTGAGTTCTTGAATAGAATTGATGAAACCATCATGTTCGAGCCACTTAACA
GAAAGATTCTTCGAAAAATTGTGGATATCCAATGGAGAGAAATCCAACAACGCTTAGCGGAATCGGGTATCGAAATAGAT
GCAACCCAAGATGTGTTGGATTATTTAGGGGAAGTTGGGTTTGATCCTCAATTTGGTGCCAGACCATTAAAGAGAACCAT
GCAACGCTTGGTATTGAATGAGTTGTCCAAACAAATTTTGAGTGGATACATCAAAAATGATAGTGCTGTTTTGGTGGACT
TGGATGCCGAAAAGCAAGTCTATTTCAAAAACGTGGACCATGTAGAGATAAGTTAA

Protein sequence :
MDFKQFTIKSQEVIQKALELCTAEQQQLIEPAHLLKGIVQVDANVTDFIFQKLGINSGLILQKLDEIINQYPKVSGQQPY
LSNATNEVLTQAKKYLKTFGDEFVAVEHLLLGVLAGSEKVAQLLKGQGLNEKKLIEVIKELRKGNKVTDQNAESKYRSLE
KYSKNLNDLAKKGKIDPVIGRDEEIRRVLQILARRTKNNPILLGEPGVGKTAIVEGLAQRIVSGDVPENLKSKTLISLDM
GLLVAGAKYKGEFEERLKAVIKEVTDSDGEIILFIDEIHTLIGAGGGGEGAMDAANLLKPALARGELHAIGATTLKEYQK
YIEKDKALERRFQQVVVDEPDAADAISILRGIKDKYELHHGVRIKDDAVIAAVELSQRYISDRYLPDKAIDLMDEAAAKL
RMEIDSLPQELDELNRRIMQLEIEREAIRREKNKDKESVLSKELADLSEKRQELKAKWEGEKAVIQGIQREKENIDKFKI
EAEQAERSGDFGKVAEIRYGKIVDSEQKLESFKEQLKVMQENSTLLKEEVDSEDIAAVVSKWTGIPLSKMIQSEREKLLH
LEEELGKRVAGQKEAITALSDAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALAEYLFSDENAMVRIDMSEYQERH
AVSRLVGAPPGYVGYDEGGQLTEAVRRKPYSVVLLDEIEKAHPDVFNILLQVLDDGRLTDNKGRIANFKNTIIIMTTNIG
SHLIQERFESLNESNKEAVLESTKEEVFNLLKKSVRPEFLNRIDETIMFEPLNRKILRKIVDIQWREIQQRLAESGIEID
ATQDVLDYLGEVGFDPQFGARPLKRTMQRLVLNELSKQILSGYIKNDSAVLVDLDAEKQVYFKNVDHVEIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-105 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-105 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cycma_2517 YP_004774487.1 ATP-dependent chaperone ClpB VFG2084 Protein 2e-101 42