Gene Information

Name : clpC (SFBM_1418)
Accession : YP_004771919.1
Strain : Candidatus Arthromitus sp. mouse isolate
Genome accession: NC_015913
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence clpC/mecB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1524856 - 1527294 bp
Length : 2439 bp
Strand : -
Note : -

DNA sequence :
ATGTTTGAAAAATTGACTGAAAGGGCTAGAAAAGTTATTAGTTATTCTGGTGATGATGCATTAAAATTAGGACATGGTTT
TATAGGAACAGAGCATATATTATTAGGATTATTAAGAGAAGATGGTCCTGCACAGAAGATACTGAATTCATTTGATGTAT
ATTATGATGATATTTTTAAAGAAATTAGAACTATATTGTCTCCAGGAGAGATAGAGATAAAGAATAGTGAAATACCATTG
ACACCTAGAACTAAAAAAGTTATAGAAAGCAGCATAGATGAGGCTAAGAAACTGGGTCATAATCACGTATCACCTGAGCA
TATATTATTGGCTATCATAAATGAACCTGATGGAGTTGCGTATAAGATATTGGATAAAAAGGGTGTATCTGTAGTAAAAA
TATGGAATCAAACTATAAATGCATTAAATGTTACAATTGATGTGCAAAATCCACATGAAAAAGAGCAACAACTTAAAAAT
CTACCGACTCCTGTGTTAGATCAGCATGGTAGAGATCTTACTAAACTGGCTAATGAAGGCAAATTGGATCCTGTTATCGG
AAGAGATACAGAAACACAGAGGGTTCTTGAAATATTATGTCGAAGAATAAAAAATAATCCATGCTTGATAGGTGATCCTG
GTGTGGGTAAAACTGCTATTATTGAGGGTTTGGCACAGAAAATAATAGAAGGCAATATTCCGGAAATATTAAAAAATAAA
CGTGTTATAACTTTAGATTTATCGTCTTTAATTGCAGGAACAAAATATAGGGGTGAGTTTGAAGAAAGATTAAAAAAAAT
AATGGAAGAGATAAAGAGGTCTAGGAATATAATTTTATTTATAGATGAGATACATACTATAATTGGTGCAGGTGGAGCTG
AGGGGGCAATAGACGCATCTAATATATTGAAACCTGCTTTGGCTAGAGGTGAAATACAATGTATAGGGGCTACAACTATT
GATGAGTATAGAAAGTATATAGAAAAAGATACGGCTCTTGAGCGGAGATTTCAGCCTATATTTGTTGGAGAACCTAATGA
AAATGAAACTATAGATATATTGATAGGTATAAGAGATAAATATGAAACGCATCATAAAGTTAAAATCACTGATGAAGCTA
TAAAATTTGCAGTTAGTTTATCAGTTAGATTTATTCCAGATAGATATTTACCAGATAAAGCTATAGATTTAATAGATGAG
GCATCAGCTAAAATAAGAGTTAGAAATTTGACGGTTCCTATTGAAGTTAAGGAAATAGAGGAAGAGATAGCAAAAGTTGG
TAAGGAGAAACAAGAAGCAATAACTTTGGAAGATTTTGAAAAAGCCGCATCTCTTAGAGATAAAGAACAGAAGCTTAAAG
AAAGATTAGAAAATTCAAAAGAGAAGTGGAAAGTTGAAAAATATGATAAGGAATTTATACTTACTGAGCAAGAATTGGCA
TCTGTTGTAGCTAGTTGGACTAAAATACCTGTTGAGAAATTAACACATACAGAGTCTGAGAAATTATTAAAATTAGATGA
TATATTGAGGAGTAGAGTTATAGATCAAAATGAAGCTGTTATATCTGTTGCCAGAGCTGTTAAACGTGGACGTGTTGGAT
TGAAGGATCCTAAAAGACCTATTGGATCATTTATATTTTTAGGCCCTACTGGAGTTGGTAAAACTGAGTTGTGTAAGGCT
TTAGCAGATGCTGTTTTTGGGAGTGAAGATAATATTATAAGATTTGATATGTCTGAATTTATGGAAAAGCATACAGTATC
AAAAATTATAGGATCACCTCCGGGATATGTTGGATTTCAAGAAGGAGGACAATTAACGGAAAAGGTAAGAAGATCTCCAT
ATTCTATTATATTATTTGATGAAATAGAGAAGGCTCATCCAGATATATTTAATATAATGTTGCAAATTTTAGAAGATGGT
CATTTAACTGATTCGAATGGCAAAAAAATTAGTTTTAAAAATACAATAATAATATTAACTTCAAATATAGGTGCAAATAT
TATTAATAAAGATTCATCTTTGGGATTTGTTAATCATAAGAATGGTGATGAAGAAGTTTATAATAAAATTAAGGATAATG
TTTTGAGTGAGCTCAAGAAAAGTTTTAGACCTGAGTTTTTAAATAGATTAGATGATATAATAGTATTTAAGCCATTAGAT
AAAAAGAGTCTTGTAAAAATATTGGATAAGATGTTAGATGATTTTAAATCAAGAGTATTAAATCAGAATATAATAATTAA
TTTTAATGATGATGTTAAAAATTATATACTTGAGAATAGCTCAAGTGAAAAATATGGAGCTAGACCATTGAGAAGGTCAA
TAACTAAGTATATTGAGGATAGTTTATCTGATCAAATATTATTAGGGAACATTAAGGCTAATGATAGTGTGGAAGTTATA
TTAAAGGATGATAAGATTTGTTATATAAAAAATACATAA

Protein sequence :
MFEKLTERARKVISYSGDDALKLGHGFIGTEHILLGLLREDGPAQKILNSFDVYYDDIFKEIRTILSPGEIEIKNSEIPL
TPRTKKVIESSIDEAKKLGHNHVSPEHILLAIINEPDGVAYKILDKKGVSVVKIWNQTINALNVTIDVQNPHEKEQQLKN
LPTPVLDQHGRDLTKLANEGKLDPVIGRDTETQRVLEILCRRIKNNPCLIGDPGVGKTAIIEGLAQKIIEGNIPEILKNK
RVITLDLSSLIAGTKYRGEFEERLKKIMEEIKRSRNIILFIDEIHTIIGAGGAEGAIDASNILKPALARGEIQCIGATTI
DEYRKYIEKDTALERRFQPIFVGEPNENETIDILIGIRDKYETHHKVKITDEAIKFAVSLSVRFIPDRYLPDKAIDLIDE
ASAKIRVRNLTVPIEVKEIEEEIAKVGKEKQEAITLEDFEKAASLRDKEQKLKERLENSKEKWKVEKYDKEFILTEQELA
SVVASWTKIPVEKLTHTESEKLLKLDDILRSRVIDQNEAVISVARAVKRGRVGLKDPKRPIGSFIFLGPTGVGKTELCKA
LADAVFGSEDNIIRFDMSEFMEKHTVSKIIGSPPGYVGFQEGGQLTEKVRRSPYSIILFDEIEKAHPDIFNIMLQILEDG
HLTDSNGKKISFKNTIIILTSNIGANIINKDSSLGFVNHKNGDEEVYNKIKDNVLSELKKSFRPEFLNRLDDIIVFKPLD
KKSLVKILDKMLDDFKSRVLNQNIIINFNDDVKNYILENSSSEKYGARPLRRSITKYIEDSLSDQILLGNIKANDSVEVI
LKDDKICYIKNT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_004771919.1 negative regulator of genetic competence clpC/mecB VFG0079 Protein 0.0 55
clpC YP_004771919.1 negative regulator of genetic competence clpC/mecB VFG0080 Protein 2e-143 51