Gene Information

Name : SPPN_04540 (SPPN_04540)
Accession : YP_004768206.1
Strain : Streptococcus pseudopneumoniae IS7493
Genome accession: NC_015875
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 880096 - 881601 bp
Length : 1506 bp
Strand : +
Note : COG0469 Pyruvate kinase

DNA sequence :
ATGAACAAACGTGTAAAAATCGTTGCAACTTTGGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTCGGTGAGGACGG
ATACTGGGGTGAAAAACTTGATGTTGAAGCTTCAGCTAAAAACATTGCTCAATTGATTGAAGCTGGTGCTAACACATTCC
GTTTCAACTTCTCACACGGTGACCACCAAGAACAAGGTGAGCGTATGGCAACTGTTAAACTTGCTGAAAAACTTGCAGGT
AAAAAAGTTGGTTTCCTTCTTGATACAAAAGGACCAGAAATCCGTACAGAATTGTTCGAAGGTGAAGCTAAAGAGTATTC
ATACAAAACTGGTGAGAAAATCCGTGTTGCAACTAAACAAGGAATCAAATCAACTCGTGAAGTGATTGCATTGAACGTTG
CTGGTGCTCTGGATATCTATGATGATGTTGAAGTTGGTCGTCAAGTGTTGGTTGACGACGGTAAACTTGGTCTTCGTGTG
GTTGCTAAAGATGACGCAACTCGTGAATTTGAAGTGGAAGTTGAAAACGATGGTATCATCGCTAAACAAAAAGGTGTGAA
TATTCCTAACACTAAAATTCCTTTCCCAGCCCTTGCTGAACGTGATAACGACGATATCCGCTTTGGTCTTGAACAAGGTA
TCAACTTTATTGCGATTTCATTCGTACGTACTGCAAAAGACGTGAACGAAGTTCGTGCAATCTGTGAAGAAACTGGAAAC
GGGCATGTTCAATTGTTCGCTAAAATCGAAAATCAACAAGGTATCGATAACTTGGATGAAATCATCGAAGCAGCTGATGG
TATCATGATCGCTCGTGGTGATATGGGTATCGAAGTACCATTCGAAATGGTTCCAGTTTACCAAAAAATGATTATCAAGA
AAGTCAATGCTGCAGGTAAAGTTGTTATCACTGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCAACTCGT
TCAGAAGTATCAGACGTATTCAACGCTGTTATCGACGGAACTGACGCTACAATGCTGTCAGGCGAGTCTGCAAACGGTAA
ATACCCACTCGAGTCAGTAACTACAATGGCTACAATAGACAAGAACGCTCAAACTCTTCTTAATGAATACGGACGTTTGG
ATTCAGATTCATTTGAACGTAACTCTAAGACAGAAGTAATGGCTTCAGCTGTTAAAGATGCTACTAACTCAATGGATATC
AAATTGGTTGTAACTCTTACTAAGACAGGTCATACTGCACGTTTGATTTCTAAATACCGTCCAAATGCTGACATCTTAGC
ATTGACATTTGATGAATTGACAGAACGTGGATTGATGTTGAACTGGGGTGTTATCCCAATGTTGACAGATGCTCCATCTT
CAACTGACGATATGTTCGAAATCGCTGAACGTAAAGCGGTAGAAGCAGGTCTCGTTGAGTCAGGCGATGATATCGTTATC
GTTGCTGGTGTACCAGTAGGAGAAGCTGTTCGTACAAATACAATGCGTATCCGCACAGTACGTTAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAQLIEAGANTFRFNFSHGDHQEQGERMATVKLAEKLAG
KKVGFLLDTKGPEIRTELFEGEAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN
GHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQTLLNEYGRLDSDSFERNSKTEVMASAVKDATNSMDI
KLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTDAPSSTDDMFEIAERKAVEAGLVESGDDIVI
VAGVPVGEAVRTNTMRIRTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-80 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-80 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-80 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-80 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPPN_04540 YP_004768206.1 pyruvate kinase VFG0479 Protein 1e-80 44