Gene Information

Name : SPPN_02350 (SPPN_02350)
Accession : YP_004767772.1
Strain : Streptococcus pseudopneumoniae IS7493
Genome accession: NC_015875
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 404115 - 406220 bp
Length : 2106 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAACAACAATTTTAATAATTTTAACAACATGGATGATTTGTTTAACCAATTGATGGGTGGTATGCGAGGATATAGTTC
TGAAAACCGTCGCTACTTGATTAATGGACGTGAAGTGACACCTGAAGAATTTGCTCACTATCGTGCAACCGGTCAATTGC
AAGGGAATGTAGAAGCTGATGGACAAATGCAACAACAGGCTTCAGGTATAAAACAAGATGGTGTCCTTGCTAAACTGGGT
CGAAACTTGACTGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
GATCCTCTCACGTCGTACCAAGAACAATCCTGTTCTGGTCGGAGATGCAGGTGTTGGTAAGACAGCTGTTGTCGAAGGTC
TTGCTCAAGCAATTGTGAACGGCGATGTTCCAGCTGCTATTAAGAATAAGGAAATTATTTCCATTGATATCTCTGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAACGTTCAAAACTTAGTCAATGAAGTAAAAGAAGCGGGAAATAT
CATTCTCTTCTTTGATGAAATTCACCAAATCCTCGGTGCTGGTTCTACTGGAGGTGACAGTGGTTCTAAGGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACGACTCAAGATGAATACCGTAACACCATC
TTGAAGAATGCAGCTCTTGCTCGTCGTTTCAACGAAGTCAAGGTCAATGCTCCTTCAGCAGAGGATACATATAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAACACCATAATGTCATCTTGCCAGATGAAGTTTTGAAAGCAGCAGTAGATTATT
CTGTTCAGTATATTCCTCAACGTAGCTTGCCAGATAAGGCTATCGACCTGGTCGATGTAACGGCGGCTCACTTGGCAGCT
CAGCATCCTGTAACAGATGTGCATGCTGTTGAACGTGAAATTGAGGTAGAAAAAGACAAGCAAGAAAAAGCTGTTGAGTC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATCGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTAGAACGAATGACCGGTATTCCAGTATCTCAAATGGGGGCT
ACGGACATCGAACGTTTGAAAGATATGGGTCATCGTTTGCAGACGAAAGTTATTGGTCAAGATAAGGCCGTTGTAGCAGT
AGCAAAAGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGCAATCGCCCAATCGGTAGCTTCCTCTTTGTAGGTCCAA
CTGGGGTTGGTAAGACTGAACTTGCTAAACAATTGGCGCTAGATATGTTTGGAACGAAAGATGCTATCATCCGTTTGGAC
ATGTCAGAATACAGCGACCGCACAGCCGTATCTAAATTGATTGGTACAACTGCAGGTTATGTTGGTTACGATGACAACAA
CAATACCTTGACAGAACGCGTCCGTCGCAATCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAG
TCATCACCCTTCTCCTTCAAGTTTTGGATGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTCAACTTCAAGAATACG
GTGATTATCGCAACTTCAAACGCAGGATTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAATTGATGGA
TCGTTTGAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAG
ATCTTTCTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTGAGC
GAAGCTGCTAAAGAATACATGACTGAGGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACA
ACAAATCCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGACATGGAAGATGGTG
TTTTGGTCATTCGTGAAAAAGCCTAA

Protein sequence :
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLQGNVEADGQMQQQASGIKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEVEKDKQEKAVESEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
TDIERLKDMGHRLQTKVIGQDKAVVAVAKAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVS
EAAKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIREKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-134 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPPN_02350 YP_004767772.1 ATP-dependent Clp protease, ATP-binding subunit VFG0080 Protein 2e-146 48
SPPN_02350 YP_004767772.1 ATP-dependent Clp protease, ATP-binding subunit VFG0079 Protein 7e-140 45