Gene Information

Name : SPPN_01040 (SPPN_01040)
Accession : YP_004767512.1
Strain : Streptococcus pseudopneumoniae IS7493
Genome accession: NC_015875
Putative virulence/resistance : Virulence
Product : type 1 capsular polysaccharide biosynthesis protein CapD
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 166900 - 168750 bp
Length : 1851 bp
Strand : +
Note : COG1086 Predicted nucleoside-diphosphate sugar epimerases

DNA sequence :
ATGAATAAAAAACTAACAGATTATGTGATTGATCTGGTGGAAATTTTAAATAAACAACAAAAGCAGGTTTTCTGGGGAAT
ATTTGATATTTTCAGTATGGTGGTTTCCATCATTGTATCTTATATTTTATTTTATGGGCTGATTAATCCAGCACCTGTTG
ACTACATTATCTATACGAGTTTGGCCTTCTTGTTTTATCAATTGATGATTGCATTTTGGGGCTTGAACGCGAGTATTAGT
CGTTACAGCAAGATTACGGATTTCATGAAAATCTTTTTTGGTGTGACTGCTAGCAGTGTCTTGTCATATAGTATCTGTTA
TGCCTTCTTGCCACTCTTCTCCATCCGTTTCATCATTCTCTTTATCTTGTTGAGTACCTTCTTGATTTTATTGCCACGGA
TTAGTTGGCAGTTAATCTACTCCAGACGCAAAAAAGGTAGTGGTGATGGAGAACACCGTCTGACCTTCTTGATTGGTGCC
GGTGATGGTGGGGCTCTCTTTATGGATAGTTACCAACATCCAACCAGTGAATTAGAACTGGTCGGTATTTTGGATAAGGA
TTCTAAGAAAAAGGGTCAAAAACTTGGTGGTATTCCTGTTTTGGGCTCTTATGACAATCTGCCTGAATTAGTCAAACACC
ATCAAATCGAGCGTGTCATCGTTGCGATTCCGTCGCTGGATCCGTCAGAATATGAGCGTATCTTGCAGATGTGTAATAAG
CTGGGTGTCAAATGTTACAAGATGCCTAAGGTTGAAACTGTTGTTCAGGGCCTTCACCAAGCAGGTACTGGCTTCCAAAA
AATTGATATTACGGACCTTTTGGGTCGTCAGGAAATCCGTCTTGACGAATCGCGTCTGGGTGCAGAACTGACAGGTAAGA
CCATCTTAGTCACAGGAGCTGGAGGTTCAATCGGTTCTGAAATCTGTCGTCAAGTTAGTCGCTTCAATCCTGAACGCATT
ATCTTGCTCGGTCATGGGGAAAACTCAATCTACCTTGTTTATCATGAATTGATTCGTAAGTTCCAAGGGATTGATTATGT
ACCTGTGATTGCGGACATTCAAGACTACGACCGTCTCTTGCAAGTCTTTGAGCAGTACAAACCTGCTATTGTTTATCATG
CGGCAGCCCACAAGCATGTTCCTATGATGGAGCGCAATCCAAAAGAAGCCTTCAAAAACAATATCCGTGGAACTTACAAC
GTTGCTAAGGCTGTTGATGAAGCTAAAGTGTCTAAGATGGTTATGATTTCGACAGATAAGGCAGTTAATCCACCAAATGT
TATGGGAGCAACCAAGCGCGTGGCGGAGTTGATTGTCACTGGCTTTAACCAACGTAGCCAATCGACCTACTGTGCAGTTC
GTTTTGGGAATGTACTTGGTAGCCGTGGTAGTGTCATTCCAGTCTTTGAACGTCAAATTGCTGAAGGTGGGCCTGTAACG
GTCACAGACTTCCGCATGACCCGTTACTTTATGACCATTCCAGAAGCTAGCCGTCTGGTTATCCATGCTGGTGCTTATGC
CAAAGATGGGGAAGTCTTTATCCTTGATATGGGCAAACCAGTCAAGATTTATGACTTGGCCAAGAAGATGGTGCTTCTAA
GTGGCCACACTGAAAGTGAAATTCCAATCGTTGAAGTTGGAATCCGCCCAGGTGAAAAACTCTACGAAGAACTCTTGGTA
TCAACCGAACTCGTTGACAATCAAGTTATGGATAAGATTTTCGTTGGTAAGGTTAATGTCATGCCTTTAGAATCCATCAA
TCAAAAGATTGGAGAGTTCCGCACTCTCAGTGGAGATGAGTTGAAGCAAGCTATTATCGCCTTTGCTAATCAAACAACCC
ACATTGAATAA

Protein sequence :
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIAFWGLNASIS
RYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRISWQLIYSRRKKGSGDGEHRLTFLIGA
GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELVKHHQIERVIVAIPSLDPSEYERILQMCNK
LGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERI
ILLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYN
VAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVT
VTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLV
STELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 3e-101 55
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 8e-102 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPPN_01040 YP_004767512.1 type 1 capsular polysaccharide biosynthesis protein CapD VFG1300 Protein 3e-98 52