Gene Information

Name : SPPN_09795 (SPPN_09795)
Accession : YP_004769227.1
Strain : Streptococcus pseudopneumoniae IS7493
Genome accession: NC_015875
Putative virulence/resistance : Virulence
Product : pneumolysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1853962 - 1855377 bp
Length : 1416 bp
Strand : -
Note : -

DNA sequence : 
ATGGCAAATAAAGCAGTAAATGACTTTATACTAGCTATGGATTACGATAAAAAGAAACTCTTGACCCATCAGGGAGAGAG
TATTGAAAATCGTTTCATCAAAGAGGGGAATCAGTTACCCGATGAGTTTGTTGTTATCGAAAGAAAGAAGCGGAGCCTGT
CGACAAACACAAGTGATATTTCCGTGACGGCTACCAATGATAGTCGCCTCTATCCTGGAGCGCTTCTCGTAGTGGATGAG
ACCTTGTTAGAGAATAATCCCACTCTTCTTGCGGTCGATCGTGCTCCGATGACTTATAGTATTGATTTGCCTGGTTTGGC
AAGTAGTGATAGCTTTCTCCAAGTAGAAGATCCCAGCAATTCAAGTGTTCGCGGAGCGGTAAACGATTTGTTGGCCAAAT
GGCATCAAGACTATGGTCAGGTCAATAATGTCCCAGCTAGAATGCAGTATGAAAAAATCACGGCTCACAGCATGGAACAA
CTCAAGGTCAAGTTTGGTTCTGACTTTGAAAAGACAGGGAATTCTCTTGATATTGATTTTAACTCTGTCCATTCGGGCGA
AAAGCAGATTCAGATTGTTAATTTTAAGCAGATTTATTATACAGTCAGCGTAGATGCTGTTAAAAATCCAGGAGATGTGT
TTCAAGATACTGTAACGGTAGAGGATTTGAGGCAGAGAGGAATTTCTGCAGAGCGTCCTTTGGTCTATATTTCGAGTGTT
GCTTACGGGCGTCAGGTCTATCTCAAGTTGGAAACTACGAGTAAGAGTGATGAAGTAGAGGCTGCTTTTGAAGCTTTGAT
AAAAGGAGTCAAGGTAGCTCCTCAGACAGAGTGGAAGCAGATTTTGGACAATACAGAAGTGAAGGCAGTTATTTTAGGGG
GCGACCCGAGTTCGGGTGCCCGAGTTGTAACAGGCAAGGTGGATATGGTAGAGGACTTGATTCAAGAAGGCAGTCGCTTT
ACAGCAGATCACCCAGGCTTGCCGATTTCCTATACAACTTCTTTTTTACGAGACAATGTAGTTGCGACCTTTCAAAACAG
TACAGACTATGTTGAGACTAAGGTGACAGCCTACAGAAACGGAGATTTACTCTTGGATCATAGTGGTGCCTATGTTGCCC
AATATTACATTACTTGGGATGAATTATCCTATGATCATCAAGGTAAGGAAATCTTGACTCCTAAGGCTTGGGACAGAAAT
GGGCAGGATTTGACGGCTCATTTTACCACTAGTATTCCTTTAAAAGGGAATGTTCGCAATCTCTCTATCAAAATTAGAGA
GTGTACCGGACTTGCCTGGGAATGGTGGCGTACGGTTTATGAAAAAACCGATTTGCCACTAGTGCGTAAGCGGACGATTT
CTATTTGGGGAACGACTCTTTATCCTCAGGTAGAGGATAAGGTAGAAAATGATTAG

Protein sequence : 
MANKAVNDFILAMDYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDE
TLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLRQRGISAERPLVYISSV
AYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRF
TADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEILTPKAWDRN
GQDLTAHFTTSIPLKGNVRNLSIKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 2e-107 44
slo YP_281505.1 streptolysin O Virulence Not named Protein 6e-97 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPPN_09795 YP_004769227.1 pneumolysin VFG1363 Protein 0.0 99
SPPN_09795 YP_004769227.1 pneumolysin VFG2275 Protein 2e-110 47
SPPN_09795 YP_004769227.1 pneumolysin VFG0074 Protein 3e-108 44
SPPN_09795 YP_004769227.1 pneumolysin VFG0976 Protein 2e-97 43