Gene Information

Name : guaA (SPPN_07120)
Accession : YP_004768710.1
Strain : Streptococcus pseudopneumoniae IS7493
Genome accession: NC_015875
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1360301 - 1361863 bp
Length : 1563 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGAGCAACATATCAACTGATTTGCAAGATGTAGAAAAAATCATCGTGCTGGATTATGGTAGCCAATATAACCAGCTGAT
TTCACGCCGTATCCGTGAGATTGGCGTTTTTTCAGAACTAAAGAGCCATAAAATTTCAGCTGCTGAAGTTCGTGAAATCA
ATCCTGTAGGAATTATCCTATCAGGTGGTCCAAACTCTGTATACGAAGATGGTTCATTTGATATTGACCCAGAAATCTTC
GAACTCGGAATTCCTATTTTGGGAATCTGTTATGGTATGCAATTATTAACCCATAAACTTGGAGGAAAAGTTGTTCCTGC
AGGTGATGCTGGAAATCGTGAATACGGTCAATCAACCCTAACACACACACCATCAGCGCTTTTTGAATCAACACCTGATG
AACAGACTGTATTGATGAGCCATGGTGATGCAGTTACTGAAATTCCTTCTGACTTTGTTCGTACAGGTACATCAGCTGAC
TGCCCATATGCAGCCATTGAAAACCCAGATAAACACATTTACGGTATCCAATTCCACCCAGAAGTTCGCCATTCTGTATA
CGGAAATGATATCCTTCGTAACTTTGCCCTTAACATCTGTAAGGCTAAAGGCGACTGGACAATGGATAACTTCATTGATA
TGCAGATCCAAAAAATTCGTGAAACCGTCGGTGATAAACGTGTCCTTCTTGGCCTATCAGGTGGGGTTGACTCTTCAGTT
GTTGGAGTTCTTCTCCAAAAGGCTATTGGCGATCAATTGATCTGTATCTTCGTAGACCACGGTCTTCTTCGTAAAGGAGA
AGCGGACCAAGTTATGGACATGCTTGGTGGTAAGTTTGGTTTGAATATCGTCAAAGCAGACGCTGCTAAACGTTTCCTTG
ACAAACTTGCTGGCGTTTCTGACCCTGAACAAAAACGTAAAATCATCGGTAACGAGTTTGTCTATGTATTTGATGATGAA
GCCAGCAAGCTCAAAGATGTGAAATTCCTTGCTCAAGGAACTCTTTATACAGACGTTATCGAGTCTGGTACGGATACAGC
TCAAACTATCAAGTCACACCACAACGTGGGTGGTCTTCCAGAAGACATGCAGTTTGAATTGATCGAACCATTGAATACTC
TTTACAAGGACGAAGTTCGTGCCCTTGGTACAGAGCTTGGTATGCCAGACCATATCGTATGGCGCCAACCATTCCCAGGA
CCAGGACTTGCTATCCGTGTCATGGGTGAAATCACTGAAGAGAAACTTGAAACTGTTCGTGAGTCGGACGCTATTCTTCG
TGAAGAAATTGCTAAAGCTGGTCTTGACCGCGATATTTGGCAATACTTCACGGTCAATACAGGCGTTCGTTCAGTTGGGG
TTATGGGTGACGGTCGTACGTACGACTACACAATTGCAATCCGTGCTATCACCTCTATTGATGGTATGACTGCTGACTTT
GCCAAAATTCCTTGGGATGTCCTTCAAAAAATCTCAGTACGTATCGTAAACGAAGTGGATCATGTTAACCGCATCGTCTA
TGATATTACAAGTAAACCACCTGCAACTGTTGAGTGGGAATAA

Protein sequence :
MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHKISAAEVREINPVGIILSGGPNSVYEDGSFDIDPEIF
ELGIPILGICYGMQLLTHKLGGKVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPSDFVRTGTSAD
CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWTMDNFIDMQIQKIRETVGDKRVLLGLSGGVDSSV
VGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLGGKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDE
ASKLKDVKFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHIVWRQPFPG
PGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF
AKIPWDVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-176 71
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-177 71
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-177 71
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-123 51