Gene Information

Name : SPPN_06270 (SPPN_06270)
Accession : YP_004768550.1
Strain : Streptococcus pseudopneumoniae IS7493
Genome accession: NC_015875
Putative virulence/resistance : Virulence
Product : pneumolysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1197665 - 1199080 bp
Length : 1416 bp
Strand : -
Note : -

DNA sequence : 
ATGACAAATAAAGCAGTAAATGACTTTATACTAGCTATGGATTATGATAAAAAGAAACTCTTGACCCATCAGGGAGAGAG
TATTGAAAATCGTTTCATCAAAGAGGGGAATCAGTTACCCGATGAGTTTGTTGTTATCGAAAGAAAGAAGCGGAGCCTGT
CGACAAACACAAGTGATATTTCCGTGACGGCTACCAATGATAGTCGCCTCTATCCTGGAGCGCTTCTCGTAGTGGATGAG
ACCTTGTTAGAGAATAATCCCACTCTTCTTGCGGTCGATCGTGCTCCGATGACTTATAGTATTGATTTGCCTGGTTTGGC
AAGTAGTGATAGCTTTCTCCAAGTGGAAGATCCCAGCAATTCAAGTGTTCGCGGAGCGGTAAACGATTTGTTGGTCAAGT
GGCATCAAGATTATGGTCAGGTCAATAATGTCCCAGCTAGAATGCAGTATGAAAAAATCACGGCTCACAGCATGGAACAA
CTCAAGGTCAAGTTTGGTTCTGACTTTGAAAAGACAGGGAATTCTCTTGATATTGATTTTAATTCTGTCCATTCGGGCGA
AAAGCAGATTCAGATTGTCAATTTTAAGCAGATTTATTATACAGTCAGCGTAGATGCTGTTAAAAATCCAGGAGATGTGT
TTCAAGATACTGTAACGGTAGAGGATTTGAGGCAGAGAGGAATTTCTGCCGATCGTCCTTTGGTCTATATTTCGAGTGTT
GCTTATGGGCGTCAGGTTTATCTCAAGTTGGAAACCACGAGTAAGAGTGATGAAGTCGAGGCTGCTTTTGAAGCTTTGAT
AAAAGGAGTCAAGGTAGCTCCTCAGACAGAGTGGAAGCAGATTTTGGACAATACAGAAGTGAAGGCGGTTATTTTAGGAG
GGGACCCGAGTTCGGGTGCCCGAGTTGTAACAGGCAAGGTGGATATGGTAGAGGACTTGATTCAAGAAGGCAGTCGCTTT
ACAGCCGATCATCCAGGTTTGCCGATTTCTTATACAACTTCTTTTTTACGGGACAATGTAGTTGCGACCTTTCAAAACAG
TACAGACTATGTTGAGACTAAGGTGACAGCTTACAGAAACGGAGATTTACTCTTGGATCATAGTGGTGCCTATGTTGCCC
AATATTACATTACTTGGGATGAATTATCCTATGATTATCAAGGTAAAGAAGTCTTGACTCCTAAGACTTGGGACAGAAAT
GGGCAGGATTTGACGGCTCATTTTACCACTAGTATTCCTTTAAAAGGGAATGTTCGCAATCTCTCTATCAAAATTAGGGA
GTGTACCGGACTTGCCTGGGAATGGTGGCGTACGGTTTATGAAAAAACCGATTTGCCACTAGTGCGTAAGCGGACGATTT
CTATTTGGGGAACGACTCTTTATCCTCAGGTAGAAGATAAGGTAGAAAATGACTAG

Protein sequence : 
MTNKAVNDFILAMDYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDE
TLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLVKWHQDYGQVNNVPARMQYEKITAHSMEQ
LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLRQRGISADRPLVYISSV
AYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRF
TADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDYQGKEVLTPKTWDRN
GQDLTAHFTTSIPLKGNVRNLSIKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 4e-106 44
slo YP_281505.1 streptolysin O Virulence Not named Protein 6e-96 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPPN_06270 YP_004768550.1 pneumolysin VFG1363 Protein 0.0 99
SPPN_06270 YP_004768550.1 pneumolysin VFG2275 Protein 2e-109 47
SPPN_06270 YP_004768550.1 pneumolysin VFG0074 Protein 7e-107 44
SPPN_06270 YP_004768550.1 pneumolysin VFG0976 Protein 2e-96 43