Gene Information

Name : SPPN_05945 (SPPN_05945)
Accession : YP_004768485.1
Strain : Streptococcus pseudopneumoniae IS7493
Genome accession: NC_015875
Putative virulence/resistance : Virulence
Product : CheY-like receiver/winged-helix DNA-binding domain-containing response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1133293 - 1133997 bp
Length : 705 bp
Strand : -
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATCAAGTTTAATATGACCAAGGAAGGGTACGA
GGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTTTGGATTTGA
TGCTTCCAGAAATTGATGGCTTAGAAGTTGCGAAGACTATTCGGAAGACTAGTAGTGTGCCTATTATCATGCTGTCAGCT
AAGGATAGCGAATTTGATAAGGTTATCGGTTTAGAGCTTGGTGCAGATGACTATGTAACCAAACCCTTCTCCAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGGCAGGAAGCAGAAAGTAAACCTC
AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGAGAAGAACTAGACTTAACC
CACCGTGAGTTTGAGCTTTTGTATCATTTGGCATCGCATGCAGGTCAAGTCATTACGCGCGAACACTTGCTTGAGACTGT
CTGGGGTTATGACTATTTTGGTGATGTCCGTACGGTTGATGTGACTGTCCGACGTCTGCGTGAGAAGATTGAAGATACGC
CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA

Protein sequence : 
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEAESKPQPIQIGDLEIVPDAYVAKKYGEELDLT
HREFELLYHLASHAGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 5e-34 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 1e-33 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_012469.1.7685629. Protein 2e-100 99
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002952.2859905.p0 Protein 1e-51 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_013450.8614421.p0 Protein 9e-52 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_007793.3914279.p0 Protein 9e-52 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_003923.1003749.p0 Protein 1e-51 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002745.1124361.p0 Protein 9e-52 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_009782.5559369.p0 Protein 9e-52 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002951.3237708.p0 Protein 9e-52 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_007622.3794472.p0 Protein 1e-51 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002758.1121668.p0 Protein 9e-52 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_009641.5332272.p0 Protein 9e-52 56
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator HE999704.1.gene2815. Protein 2e-49 55
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_012469.1.7686381. Protein 2e-41 48
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator AE016830.1.gene1681. Protein 5e-44 46
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator FJ349556.1.orf0.gene Protein 2e-40 45
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator CP004022.1.gene3215. Protein 2e-33 44
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator CP001918.1.gene5135. Protein 6e-27 44
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator HE999704.1.gene1528. Protein 2e-32 43
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator AM180355.1.gene1830. Protein 6e-37 43
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002695.1.915041.p Protein 3e-31 43
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator BAC0533 Protein 3e-31 43
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator CP000034.1.gene3834. Protein 3e-31 43
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator CP000647.1.gene4257. Protein 3e-31 43
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator CP001138.1.gene4273. Protein 2e-31 43
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator AF162694.1.orf4.gene Protein 9e-33 42
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator AF155139.2.orf0.gene Protein 7e-38 42
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator DQ212986.1.gene4.p01 Protein 2e-35 42
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_014475.1.orf0.gen Protein 2e-35 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_005054.2598277.p0 Protein 2e-35 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator AE000516.2.gene3505. Protein 2e-33 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002951.3238224.p0 Protein 9e-36 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_007793.3914065.p0 Protein 9e-36 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002758.1121390.p0 Protein 9e-36 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_010079.5776364.p0 Protein 9e-36 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002952.2859858.p0 Protein 9e-36 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_007622.3794948.p0 Protein 9e-36 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_003923.1003417.p0 Protein 9e-36 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_013450.8614146.p0 Protein 9e-36 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator BAC0039 Protein 4e-27 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator CP001138.1.gene2239. Protein 7e-28 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator CP000034.1.gene2186. Protein 4e-27 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator NC_002695.1.916589.p Protein 4e-27 41
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator BAC0596 Protein 7e-28 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator VFG1389 Protein 3e-31 45
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator VFG1563 Protein 3e-34 42
SPPN_05945 YP_004768485.1 CheY-like receiver/winged-helix DNA-binding domain-containing response regulator VFG1702 Protein 4e-34 42