Gene Information

Name : MELS_2030 (MELS_2030)
Accession : YP_004767075.1
Strain : Megasphaera elsdenii DSM 20460
Genome accession: NC_015873
Putative virulence/resistance : Resistance
Product : arsenite-activated ATPase ArsA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : -
Position : 2236171 - 2237904 bp
Length : 1734 bp
Strand : -
Note : -

DNA sequence :
GTGATCCTCTATGATCCCTTTCGCGTCGTCCAGACGAAATACCTCTTCCTGACCGGCAAGGGCGGCGTCGGCAAGACGTC
TGTCGCCTGTGCTACGGCTGTCGCTCTGGCCGATGCCGGGAAGAAGGTCCTGCTCATCAGTACCGACCCGGCGTCGAACC
TGCAAGACGTCTTTTCTATGGAACTGACTAACAAGGCTACGGCCATTGACGCCGTGCCTAATCTGGCTGTGGCCAATCTG
GATCCGGTCCAGGCCGCTGCCGAATATAGGGAAAGCGTCATCGGCCCTTATCGCGGCCTTTTGCCGGAAGCAGCCCTGCG
CAACATGGAAGAACAGCTGTCCGGCTCTTGTACTGTAGAAATCGCCGCCTTCAATGAGTTCACCAATTTCCTCACCGACG
AAACCGTCGCCCGCGATTACGACCACATCCTTTTCGATACGGCGCCGACAGGCCACACCCTGCGCATGCTGCAGCTGCCG
TCGGCGTGGAGCCAGTTCATCCAGAAGAGCAAACACGGCGCGTCCTGCCTGGGCCAGCTGTCGGGGCTGGAATCGCGGAA
AGAACTGTACAAGCAGGCCGTCCAGACCCTGGCCGACGGGGCTCAGACGACGATGCTCCTCGTCGCCCGTCCCGATAGCC
TGCCCCTGAAAGAAGCGGCGCGGGCGTCGAAGGAACTGGCCGCCCTGGGCATTGCCAACCAGCAGCTCATCATCAACGGC
CTCCTGCCTTCCTACGATGACGATGCGACCAAGACCTTATATGAAAAGCAGCAGGCTGCCTTGCAGGCCATGCCTGGGGC
TATTTCCGATTTACCGCGTTTCCAGATTCCCTTGCGGACGTACAATATCACCGGCTTGGACCACGTCCGGGCCCTGCTCA
AAGGGGAAGTGAAGGAAGCGGCGACGGAACTGACGCTGGAATGGGTCCAGCCCCTGCAGGCCGTCATCGACGATTTGGAA
AGCAGCCATCGCAAGGTCATCTTCACCATGGGCAAAGGCGGCGTCGGTAAGACGACTGTCGCCGCAGCCATCGCCTTGGG
CCTGGCCCGCCGCGGCCATCGCGTCCACTTGACGACGACCGACCCGGCCGCCCATTTGCAGTATATCGTCAGCCAGACGG
ACAACCTGACCTTGAGCCATATCGACGAAGGGGAAGAGCTGAGAAAATACCAGGATGAAGTCCTGAACCAGGCCAAAGCC
AACGGCCTGGGCCCGTCGGACCTGGCCTATATCGAAGAAGACCTGCGTTCGCCGTGCACCCAAGAAATTGCCGTCTTCCA
CGCCTTTGCCGATATCGTCGAAGCCGCCGACGACCAGATCGTCGTCATCGACACGGCGCCGACAGGCCATACGCTGCTGC
TCCTGGAATCGACGGAAAGCTACGATAAGGAAATCCGCCGGACCCATGGCTCGACGCCGCCGTCGGTACAGCACTTGCTG
CCGCGTCTGAAAGGGAAGGAAACGGAAGTCGTCATCGTCACCTTGCCCGAAGCGACGCCGGTATACGAAGCCCTGCGCCT
GGAAGCGGACCTGAAGCGGACCAAGCTGCGCTCGAAGTGGTGGGTCATCAACAAGTCCTTTTATCAGGCCAAGACGACGA
GCCCTTTGTTAAAGGCCAAAGCCTCGCATGAAATCCCTTGGATCAACAAAGTCGATGAACATACAAAAGGCCACACGGCC
CTCATCGCCTGGCGCCCAGATGAAGTCCGCGGCGACGTCCTAGGGACGTTGTAG

Protein sequence :
MILYDPFRVVQTKYLFLTGKGGVGKTSVACATAVALADAGKKVLLISTDPASNLQDVFSMELTNKATAIDAVPNLAVANL
DPVQAAAEYRESVIGPYRGLLPEAALRNMEEQLSGSCTVEIAAFNEFTNFLTDETVARDYDHILFDTAPTGHTLRMLQLP
SAWSQFIQKSKHGASCLGQLSGLESRKELYKQAVQTLADGAQTTMLLVARPDSLPLKEAARASKELAALGIANQQLIING
LLPSYDDDATKTLYEKQQAALQAMPGAISDLPRFQIPLRTYNITGLDHVRALLKGEVKEAATELTLEWVQPLQAVIDDLE
SSHRKVIFTMGKGGVGKTTVAAAIALGLARRGHRVHLTTTDPAAHLQYIVSQTDNLTLSHIDEGEELRKYQDEVLNQAKA
NGLGPSDLAYIEEDLRSPCTQEIAVFHAFADIVEAADDQIVVIDTAPTGHTLLLLESTESYDKEIRRTHGSTPPSVQHLL
PRLKGKETEVVIVTLPEATPVYEALRLEADLKRTKLRSKWWVINKSFYQAKTTSPLLKAKASHEIPWINKVDEHTKGHTA
LIAWRPDEVRGDVLGTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 8e-103 47
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 3e-106 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MELS_2030 YP_004767075.1 arsenite-activated ATPase ArsA BAC0571 Protein 6e-104 46
MELS_2030 YP_004767075.1 arsenite-activated ATPase ArsA BAC0030 Protein 2e-101 46
MELS_2030 YP_004767075.1 arsenite-activated ATPase ArsA BAC0572 Protein 3e-101 46