Gene Information

Name : MELS_1968 (MELS_1968)
Accession : YP_004767013.1
Strain : Megasphaera elsdenii DSM 20460
Genome accession: NC_015873
Putative virulence/resistance : Unknown
Product : DNA topoisomerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 2157579 - 2159714 bp
Length : 2136 bp
Strand : -
Note : -

DNA sequence :
ATGAAACTTTTTATTGCCGAAAAACCGAGCATGGCCCGGGAACTGGCGAAGTGCCTGCCGGAGCCGCACCAGCGGGGGAA
CGGCTGTATCCGTACGGGCGGCGGCATCGTGACCTGGGCTTATGGCCATGTCTTGCAGCAGGCTGAACCCCAGGACTATG
ATCCCAAGTACAAGCGCTGGAATGCCGATGACTTGCCGATCATCCCCCAAAAGTGGAAGCTCCTGGTCAGTCCGGCCAGC
AAGGATCAGTTCAAGGTCATTACGGACCTCATCGCCAGTCCCGACGTCGATACCATCGTCAACGCCGGGGACCCGGACCG
GGAAGGGCAGCTGCTCATCGACGAAATCCTCGACTACGTCGGCAATAAGAAGCCTGTCGAACGGATCCTCCTGAATGCCC
TCGATGAAAAGAGCATCCACGAATCCCTCGACGATTTACGCAGCAACGGTGATTTCGTCCACCTCAAGGAATCAGCCCTG
GCCCGCAGCCGCGCCGACTGGCTCATCGGCATGAACCTGTCCCGGGCGTATACCCTGGCTGCCCGCCGCCAGGGGCACCG
CGTCGTCTTTCCCATTGGCCGCGTCAAGACGCCGACCTTGGCCCTCGTCGTCCGCCGCCAGCGGGAACTGGACAACTTCG
TGCCCGTCACGTATTACGTCGTCAAAGCCGATTTCCTTCATAAGAACGGCGTCATCCGCGCCCAATGGCAGCCCCGCGAT
ACCCAGGGCGGCCTCGATCCGGAAGGGCGCTGTGTCGATGAAAAGACGGCCCGGTCCATCCTCGAACGCCTCCAGGCTCG
GCCTGACGGTACGATTGTCGAGAACAAGAAGACCAAGAAGAAAGAGGCCCAGCGCCTGCCCCTGTCCCTGTCGTCCCTGC
AGGTCCTGGCCGGCAAGCGGTATGGCTACACGCCGCAGCAGGTCCTCGATACGGCCCAGGAACTGTACGAACGGAAACTG
ACGACCTATCCCCGGTCGGACTGCGAATATCTGCCGGTGAACCAGCGCAAGGACGTACCGCGGATCTTGCAGAACATCGG
TGCCTTGGAAGCGGGGAAGCTGGCGGAATGGGCGGCCGGTGCCGACGGCAAGATACGCAGCCGCGCCTGGAACGACAGCA
AGATCACGGCCCATCACGCCATCATCCCGACGACCGTAGCCTGCCCCTTCGATAAATTGACGTCTATGCAGCAGCATATC
TACTATCTCGTCGCCCAGGCCTATCTGGCCCAGTTCTATCCCATCCATGAATACGACCAGACGCGCATGGTCATCGAAGC
CGCTGACGAAACCTTTATCGCCCACGGCAAGACCGTCACCGTGCCGGGCTGGAAAGTCCTCTATCAGAGCGATAAGCATG
ACGAGGAAGACGAAGAAAAGGGGACCCTGCCGGCGGTCCGCAAGGGCGACGGCGTCCACTACCAGAACGGCCAGGTCGAC
AAGAAAGCGACGAAGCCGCCGCCGCGGTTCACGCCGTCGACGCTCCTGGCAGCGATGAAGGAAATCTATAAGTACGTCAA
GGATGAAAGCCTGAAGAAGAAATTGAAAGAAGTCCAGGGCATCGGCACCGAAGCGACGCGGGCGACGATCATCCAGGAAC
TCATCCAGCGCAAATTCCTGACGACAGAAGGGAAGAAGAAGTACCTCAAGCCAACAGACGACGCGTATCTCCTCGTCGAT
TCCCTGCCGGATGAAATGCTCTATCCCGACGAAACGGCGGTCTGGGAAGAACGGCTCTATCAGATGAGCCTGGGCAAGGA
TGACCTCAACCACTTCCTGCACGACCAGTTGTCCTTCCTGGATACCTTAGTCACGGCAGCCCGGAAAGTTGTCATGCACC
TGGCCGGCATCAAGGTCTGTCCCGTCTGCGGCAGCGCCATGGTCAAGCGCCACGGCAAATACGGCGACTTCTACGGCTGC
AGCAATTACCCGTCGTGCCGCCACACCGAGCCCGTCGAGGGAGAAAAGAAACGGCCCGACGCCAAGCCGTCGCCCTATCC
CTGCCCGCGCTGCCATAAAGGGACCTTCCAGAAACGGACTGGCCCGTATGGCCCGTTCTGGGTCTGCAGCCAGGAAGGCT
GCAACACCAAATGTGCCGACGTCGACGGCGTGCCCAGCCTCTACGCTAAACATTAG

Protein sequence :
MKLFIAEKPSMARELAKCLPEPHQRGNGCIRTGGGIVTWAYGHVLQQAEPQDYDPKYKRWNADDLPIIPQKWKLLVSPAS
KDQFKVITDLIASPDVDTIVNAGDPDREGQLLIDEILDYVGNKKPVERILLNALDEKSIHESLDDLRSNGDFVHLKESAL
ARSRADWLIGMNLSRAYTLAARRQGHRVVFPIGRVKTPTLALVVRRQRELDNFVPVTYYVVKADFLHKNGVIRAQWQPRD
TQGGLDPEGRCVDEKTARSILERLQARPDGTIVENKKTKKKEAQRLPLSLSSLQVLAGKRYGYTPQQVLDTAQELYERKL
TTYPRSDCEYLPVNQRKDVPRILQNIGALEAGKLAEWAAGADGKIRSRAWNDSKITAHHAIIPTTVACPFDKLTSMQQHI
YYLVAQAYLAQFYPIHEYDQTRMVIEAADETFIAHGKTVTVPGWKVLYQSDKHDEEDEEKGTLPAVRKGDGVHYQNGQVD
KKATKPPPRFTPSTLLAAMKEIYKYVKDESLKKKLKEVQGIGTEATRATIIQELIQRKFLTTEGKKKYLKPTDDAYLLVD
SLPDEMLYPDETAVWEERLYQMSLGKDDLNHFLHDQLSFLDTLVTAARKVVMHLAGIKVCPVCGSAMVKRHGKYGDFYGC
SNYPSCRHTEPVEGEKKRPDAKPSPYPCPRCHKGTFQKRTGPYGPFWVCSQEGCNTKCADVDGVPSLYAKH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 5e-118 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 5e-118 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 4e-118 41