Gene Information

Name : MELS_1617 (MELS_1617)
Accession : YP_004766663.1
Strain : Megasphaera elsdenii DSM 20460
Genome accession: NC_015873
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 1778600 - 1781611 bp
Length : 3012 bp
Strand : +
Note : -

DNA sequence :
ATGGCTTTTACGGATAAAACGGAAAAGGGTTTTGAAACGCTCATCGTGAACTGGCTGGTAGATCAGAATGGTTACCAGCA
GGGCACCAATGAAGACTACAACAAAGAATATGCCATCGATGAAACCCGGCTCTTTCGCTTTTTGAATGATACTCAACCCA
AAGAGATGGCAAAGCTCGGCGTCAACCAGAGTGACCAGAAGAAGCGGCAGTTTTTGAACCGCCTTTCTGGAGAAATCACC
CGGCGCGGCATTATCGACGTGCTGCGCAATGGCATCAAAGCCTATCCGGCTGACCTGATTTTGTTCTATTTCACGCCGAC
AGAAAACAATGAGCAGGCGAAGCGGCTGTTTGACCAGAATATTTTCAGCGTTACCCGACAGTTGCGCTATGCTATCGATG
CGTCGAAACTGGCACTGGACCTCTGCCTGTTCATCAACGGTCTGCCCGTCATTACCATAGAGCTGAAAAATCATTTCACG
GGACAGACAACAGCCGATGCTGTGGAACAGTATAAAAAAGACCGCAATCCCAGGGAACTGCTGTTTTCCTTCAAGCGCTG
TATCGTACATTTTGCCGTAGATGATCAGACGGTTCAGTTCTGTACGAAACTTTGCGGAAAGGCCAGCTGGTTCCTGCCTT
TCAATAAAGGGTACCACGATGGGGCCGGGAATCCTCCCAACCCTGAAGGCATCATGACGGACTACTTGTGGAAAGATATC
CTGACGAAGAAGAAACTGTCCCGTATCATCGAGAATTATGCCCAGGTCGTCGTCGAGGAAAATCCGGAAACCCGGAAGAA
ATCGGTCAAACAGATCTGGCCGCGCTATCATCAGTTGGATTGTGTAGAAAAACTCCTGGCCGATATCAGGCAGTACGGTG
TGGGAAAACGCTATCTCATCCAGCACAGCGCCGGGTCGGGCAAATCCAATTCCATTGCCTGGCTGGCCCATCAGCTGATT
GGACTGGAACGGGATGGACGGCCTATGATTGATTCGGTCATCGTCGTAACGGACCGGCGGATTCTGGACAAGCAGATCCG
GGATACGATTAAACAGTTCATGCAGGTAAAGAATACCGTCGTATGGGCTCGTCATTCGGGTGACTTGAAAAAGGCTATCC
AGGATGGCAAACGGATCATTGTGACGACAGTCGAGAAGTTCCCTTATATTTCCCAGGAAATCGGCCAGGAACACATGAAC
CATACCTTTGCTATCATCATCGACGAAGCCCATTCGGGACAGAGCGGGCGGAACGCAGCCAGTATGAATCTGGCCCTTTC
CGGGATGGCTTCGGACAGCGAACTGGATAATGAAGACAAAATCAACGCCATGGTAGAGGGACGGAAACTGGTAAAAACGG
CCAGCTATTTTGCCTTTACGGCCACCCCAAAAAATAAAACGGAAGAGGTATTTGGCACGCCTTATGAAGAAGACGGCAAA
ATTAAACACCGGCCCTTCCATGTCTATACTATGAAACAAGCCATTCAGGAAGGCTTCATCCTGGATGTGCTGAAGAATTA
CGTGACCATCGACAGTTGGTATAAGATTGCCAAAAAGGTGGAAGACGATCCCATGTTTGACAAGAAGCGGGCTCAGAAGA
AACTGCGCTCCTTTGTCGAAGGGAATCCCGATGTCATTGCCAAGAAAGCGGCGATGATGGTCGATCATTTCCACGAACAG
ATTATTGCCAGGAAGAAACTGGGCGGCCAATCTCGCGCCATGGTGGTGACGGCCAGTATTCCCCGTTGCATTGAAACGTA
CTATGCCGTTACCCAGTGTCTTGCCGACCGGCACAGCCCTTATAAGGCTATCATCGCTTTTTCCGGGGAATGTAGCTATC
ACGGCCAGGAACCAGTATTGACTTCGGCCGAGATGAATGGCTTCCCAGACGCCAAGATTCCCCAGAAATTCAAGAAGGAC
CCGTACCGGCTGCTGGTCGTGGCCGACATGTTCCAGACGGGCTTTGACGAACCGCTGCTCCAGACTATGTATGTAGACAA
ACCCCTTTCGGACATTGCGGCCGTCCAGACCCTGTCCCGGCTGAATCGGGCGGCGCCGGGCAAGGATGAAGTCTATGTGT
TGGATTTTGCCAACAAGGCGGAAACCATCGAAAAAGCCTTTTCTCGATTCTACCGGACGACGATTCTGTCTGGGGAAACG
GACCCCAATAAGCTCTACGACCTGATTTCCCTGATGGAAGGTTATCAGGTCTATGACCACAGCGACGTAGATAAAGTAGT
GGACCTGTTTCTGAACGGCGGGGAACGGGACCGGTTGGATCCGCTTCTTGATCCATGTGTGGCCCTTTATAATCAGCTGG
AAACGGACGACCAGATTCAGTTTAAGAGTGCTGCCAAGGCTTTTGTGCGGACCTATGGTTTCCTGGGGTCTATTCTTCCA
TATGGCAATGCAGCGTGGGAAAAATTATCTATTTTCCTGAACCTGCTGATTCCCAAACTGCCATCGCCTCAGACTGATGA
CCTGTCAGAGGGTATCTTGTCCGCTGTGGACCTGGACAGTTATCGGAACGAGGCACGGGAAGCCGTAGCCATCAAACTGG
AAGATGAAGATGCTGAAATCGACCCTGTGCCGACAGGGAAGGTTGGCCACATAGTGGAACCGGAAATGGACCCCTTATCG
CAGATTATTTCAGAATTCAATGACATGTTCGGGAATATCCAATGGAACGATGCCGATAACGTACAACAACAGCTTCTGCG
TATCCCAGTCATGGTTTCCCACGATGAGAAGTACCGCAATGCTATGAAGAACTCTGATGAACAGGAAGCCCGGACTGAGG
GCGAACGGGCCTTGCAGCAGGTCATTTTCTCTATCATGGCAGATAATATGGAACTTTTCAAACAATTCCAGGACAATCCA
TCCTTCAAGAAATGGCTGACCGACATGGTGTTCAACCTGACCTATAATAAGGAAGGTAAGTCCTATGAAGCGCCAAGCGA
TTGCCAATATTCTATTCCAAAGCAAAAAGGTGGGATGGTAGCAGAGAAGTAA

Protein sequence :
MAFTDKTEKGFETLIVNWLVDQNGYQQGTNEDYNKEYAIDETRLFRFLNDTQPKEMAKLGVNQSDQKKRQFLNRLSGEIT
RRGIIDVLRNGIKAYPADLILFYFTPTENNEQAKRLFDQNIFSVTRQLRYAIDASKLALDLCLFINGLPVITIELKNHFT
GQTTADAVEQYKKDRNPRELLFSFKRCIVHFAVDDQTVQFCTKLCGKASWFLPFNKGYHDGAGNPPNPEGIMTDYLWKDI
LTKKKLSRIIENYAQVVVEENPETRKKSVKQIWPRYHQLDCVEKLLADIRQYGVGKRYLIQHSAGSGKSNSIAWLAHQLI
GLERDGRPMIDSVIVVTDRRILDKQIRDTIKQFMQVKNTVVWARHSGDLKKAIQDGKRIIVTTVEKFPYISQEIGQEHMN
HTFAIIIDEAHSGQSGRNAASMNLALSGMASDSELDNEDKINAMVEGRKLVKTASYFAFTATPKNKTEEVFGTPYEEDGK
IKHRPFHVYTMKQAIQEGFILDVLKNYVTIDSWYKIAKKVEDDPMFDKKRAQKKLRSFVEGNPDVIAKKAAMMVDHFHEQ
IIARKKLGGQSRAMVVTASIPRCIETYYAVTQCLADRHSPYKAIIAFSGECSYHGQEPVLTSAEMNGFPDAKIPQKFKKD
PYRLLVVADMFQTGFDEPLLQTMYVDKPLSDIAAVQTLSRLNRAAPGKDEVYVLDFANKAETIEKAFSRFYRTTILSGET
DPNKLYDLISLMEGYQVYDHSDVDKVVDLFLNGGERDRLDPLLDPCVALYNQLETDDQIQFKSAAKAFVRTYGFLGSILP
YGNAAWEKLSIFLNLLIPKLPSPQTDDLSEGILSAVDLDSYRNEAREAVAIKLEDEDAEIDPVPTGKVGHIVEPEMDPLS
QIISEFNDMFGNIQWNDADNVQQQLLRIPVMVSHDEKYRNAMKNSDEQEARTEGERALQQVIFSIMADNMELFKQFQDNP
SFKKWLTDMVFNLTYNKEGKSYEAPSDCQYSIPKQKGGMVAEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1765 NP_231400.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 5e-167 42
VC0395_A1363 YP_001217306.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 5e-167 42
VPI2_0013c ACA01830.1 type I restriction enzyme HsdR Not tested VPI-2 Protein 3e-166 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MELS_1617 YP_004766663.1 hypothetical protein VFG1098 Protein 2e-167 42