Gene Information

Name : MELS_1340 (MELS_1340)
Accession : YP_004766388.1
Strain : Megasphaera elsdenii DSM 20460
Genome accession: NC_015873
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1470252 - 1472000 bp
Length : 1749 bp
Strand : +
Note : -

DNA sequence :
ATGCTGAAAAAAACAAAGATCGTCTGCACCTTAGGCCCCAGTTCCAATACCCCGGAAATTATCGAAAAGATGATTAAAGC
CGGCATGAACGTTGCCCGCTTTAATTTCTCCCACGGTTCTCATGAAGAACATAAACAGCGCATCGACATGGTCCGCGCTG
CCTCCCAGAAACTGGGTATCCCTGTGGCACTGCTCCTGGACACGAAAGGCCCGGAAATCCGTTTGGGCAAATTTAAGAAT
GGCTCGATCATGATGGAAGCCGGCAAGGACTTCACCTTGACGGCCCGTGACATCGAAGGCGACGAAACGATTGCCTCCAT
GAACTATAAAGAACTGCCGCAGGACGTCAAAGCCGGCGACCACATCCTCTTGTCGGACGGCCTAGTCAACTTGGAAGTTG
TCAGCGTCGAAGGCGAAGATATCCATACGAAGATCCTCAACAGCGGCAAGATGAGCGACCGCAAGCGCGTTGCCGTACCG
GGCATCGCCATCAACCTGCCGGCCGTTTCTGAAACCGATGCCGCCGACATCGAATTTGGCTGCCGCATGAATATGGACTG
GATTGCCGCTTCTTTCATCCAGCGCGGCAAAGATGTCCTGACGATCCGCAAGATTTTGGAAAAACACGACAGCCACATGA
AGATCATCTCTAAAATCGAATGTCAGGCTGCAGTCAACAACATCGACGATATCATTAAGATGAGCGACGGCATCATGGTC
GCCCGTGGTGACCTCGGCGTCGAAGTCCCGGCGGAAGAAGTACCGATGCTCCAGAAAGTCCTCATCCATAAATGCCAGGC
TGCGGGCAAACCGGTCATTACGGCTACGCAGATGCTGGAATCCATGTGCAACAATCCGCGTCCGACCCGTGCTGAAACGA
GCGACGTTGCCAACGCCATCCTCGACGGCACCGATGCCATCATGCTCAGCGGCGAAACGGCTGGCGGCCTCTATCCGGTA
GAAGCCGTTGAAACCATGGCCCGCGTCGCTACCTTTACGGAAAGCAACTTCACGCCGGAATCCTATGAAGATGTCGACGC
CGAATCGACGACGACGACGGAATCCATCGGCAAAGCCGTCGTCAAGATTGCCAAAGACCTCCACGCTGCGGCCATCATCG
CTTCGACGGAACGCGGCGGCACAGCGCAGATGATTTCTAAATTCCGCCCGGCCTGCCCGATTGTGGCCGTATCGCCGCAC
GAAGCCATCGTCCGCCGCTTGCAGCTCAACTGGGGCGTCCAGGCTGTTACTGGCAAAGAAGCGAACGACACTGACGCCGT
CGTCGATAACGCTATCTTCGCAGCCCTCGACAACGACCTCATCAAAGCCGGCGACCTCGTCGTCCTTACGGCCGGTGTCC
CCGTTGCCAAAGCCGGTTCGACCAACATGATCCGCGTCCAGGTCGTCGGCGACGTCCTCCTCCGCGGTACCGGTATCGGC
CGTAATTCGGCCATCGGCAAAGTCTGTGTCGCTGAATCGAAAGAAGACCTGGAAAAGAACTTCAGCGACGGCTGCATCCT
CGTCCTCCGTTCGGCCCGCGCTGATTTCGTCGATTATATGAAACGGGCCAGCGCCATCGTCTCCGAAGAAGTCGGCCTGA
CCAGTGAATCAGCCATCGTCGCCATCACCTTGGGCATCCCGACCGTCGTCGGCGCAGCTCATGCCGTAGACACTCTGGAA
AATGGCGAAATCGTCACCGTAGACGCCAGCCGCGGCACCATCTTCCGCGGCGAAGCCAACGCACGCTAA

Protein sequence :
MLKKTKIVCTLGPSSNTPEIIEKMIKAGMNVARFNFSHGSHEEHKQRIDMVRAASQKLGIPVALLLDTKGPEIRLGKFKN
GSIMMEAGKDFTLTARDIEGDETIASMNYKELPQDVKAGDHILLSDGLVNLEVVSVEGEDIHTKILNSGKMSDRKRVAVP
GIAINLPAVSETDAADIEFGCRMNMDWIAASFIQRGKDVLTIRKILEKHDSHMKIISKIECQAAVNNIDDIIKMSDGIMV
ARGDLGVEVPAEEVPMLQKVLIHKCQAAGKPVITATQMLESMCNNPRPTRAETSDVANAILDGTDAIMLSGETAGGLYPV
EAVETMARVATFTESNFTPESYEDVDAESTTTTESIGKAVVKIAKDLHAAAIIASTERGGTAQMISKFRPACPIVAVSPH
EAIVRRLQLNWGVQAVTGKEANDTDAVVDNAIFAALDNDLIKAGDLVVLTAGVPVAKAGSTNMIRVQVVGDVLLRGTGIG
RNSAIGKVCVAESKEDLEKNFSDGCILVLRSARADFVDYMKRASAIVSEEVGLTSESAIVAITLGIPTVVGAAHAVDTLE
NGEIVTVDASRGTIFRGEANAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-91 46
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-91 46
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-91 46
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-90 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MELS_1340 YP_004766388.1 pyruvate kinase VFG0479 Protein 2e-91 46