Gene Information

Name : MELS_1156 (MELS_1156)
Accession : YP_004766205.1
Strain : Megasphaera elsdenii DSM 20460
Genome accession: NC_015873
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1279910 - 1281388 bp
Length : 1479 bp
Strand : -
Note : -

DNA sequence :
ATGAAACACGTCATCCGCCCTTCTTACGATTTATATATTAACGGCCGCTGGGTCCCGTCCAGCGACGGTTCTACTTTTAA
AGCCATCAATCCGGCCAACGGCGACGTCCTCTCCGTCTGTGCCGAAGCGACGCAGGACGATGTCAATGCCGCCGTCCGCG
CAGCCCAGGCCGCTTTCCCGGCCTGGAAAAAAGTATCCCCCGTCAAACGGCAGGCAATCCTCCTGAAAATCGCCGACATC
ATCGAAAAGAATGCTGATACGCTGGCCCTCATCGAAACCCTGGATAACGGCAAGCCCATCCGGGAAACGAAAGCCATCGA
CATCCCGGCAGCGGCCGACCATTTCCGCTATTTCGCCGGTGTCCTCCGCAGTGAAGACGGCCGGGCATCGACGCTGGACG
ACCACACGCTGAGCCTGGTCATCCACGAACCGATTGGCGTCGTCGGCCAGATCATCCCCTGGAACTTCCCCTTCCTCATG
GCCGCCTGGAAACTGGCACCGGCCCTGGCTGCCGGCTGTACGATCATCCTCAAGCCGTCGAGCACGACGTCCCTCAGCGT
CCTGGAACTGATGCACCTCCTGGAAGGCGTCCTGCCGGACGGCGTCGTCAACGTCATCACCGGTAAAGGCTCCCGGTCGG
GCCAGTACATCCTCGACCATCCGGACATCCAGAAACTGGCCTTCACAGGCTCTACGGAAATCGGCCGCGACGTCTATAAG
GCAGCTCAGGAAAAACTCATCCCGGCCACCTTGGAATTAGGCGGCAAATCGGCAAACATCTTCTTCGACGACTGCGATTG
GGACATGGCCATGGACGGGGCCCAGCTGGGCATCCTCTTCAACCAGGGCCAGGTCTGCTGCGCCGGTTCCCGCATCTTCG
TCCAGAAAGGGATCTACGACAAATTCGTCGCTGAACTGGCAGAACGCTTCAACCGCGTCAAAGTCGGCCTGCCCTGGCTG
GAAGACACGCAGATGGGCGCCCAGATCGACGGCCGTCAGGTCGAAAAGATCCTCAGCTACATCGAAATCGGCAAACAAGA
AGGAGCACGCCTGGTCTGCGGCGGCGAAAAAGTCACGACAGACGGACTGGAAAAGGGCAATTTCATCAAGCCGACGATCT
TCGCCGACGTCACCAACGACATGCGCATTGCCCAGGAAGAAATCTTCGGCCCTGTCGTCTGCATCCTGCCCTTTGAAACG
GAAGACGAAGTCATCGCCATGGCCAATGACAGCGAATACGGCTTAGGCGGCGCCGTCTGGACGCGCGACATCAACCGGGC
CCTGCGCGTAGCCAAAGGCGTCGAAACGGGCCGCATGTGGGTCAATACCTACAACGCCCTGCCGGCCGGCGCACCTTTCG
GCGGCTACAAGCTCTCCGGCATCGGCCGCGAAACGGATAAGACGACCATGCGCCATTACATGCAGACCAAGAACATCTTC
ATCAACCTCTCGGAAAAACCGAGCGGCTTATACGAATAA

Protein sequence :
MKHVIRPSYDLYINGRWVPSSDGSTFKAINPANGDVLSVCAEATQDDVNAAVRAAQAAFPAWKKVSPVKRQAILLKIADI
IEKNADTLALIETLDNGKPIRETKAIDIPAAADHFRYFAGVLRSEDGRASTLDDHTLSLVIHEPIGVVGQIIPWNFPFLM
AAWKLAPALAAGCTIILKPSSTTSLSVLELMHLLEGVLPDGVVNVITGKGSRSGQYILDHPDIQKLAFTGSTEIGRDVYK
AAQEKLIPATLELGGKSANIFFDDCDWDMAMDGAQLGILFNQGQVCCAGSRIFVQKGIYDKFVAELAERFNRVKVGLPWL
EDTQMGAQIDGRQVEKILSYIEIGKQEGARLVCGGEKVTTDGLEKGNFIKPTIFADVTNDMRIAQEEIFGPVVCILPFET
EDEVIAMANDSEYGLGGAVWTRDINRALRVAKGVETGRMWVNTYNALPAGAPFGGYKLSGIGRETDKTTMRHYMQTKNIF
INLSEKPSGLYE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-99 53
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-104 52
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-104 52
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-104 52
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-104 52
hpaE AAO17179.1 HpaE Not tested tcd island Protein 9e-73 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MELS_1156 YP_004766205.1 aldehyde dehydrogenase VFG0082 Protein 5e-100 53