Gene Information

Name : clpB2 (CVAR_0506)
Accession : YP_004758928.1
Strain : Corynebacterium variabile DSM 44702
Genome accession: NC_015859
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 585837 - 588461 bp
Length : 2625 bp
Strand : +
Note : ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTCGAGAGGTTCACTGACCGGGCGCGGCGCGTCGTCGTGCTGGCGCAGGAGGAAGCCCGCGCGCTCAACCACAACTA
CATCGGTACCGAGCACATCCTGCTCGGTCTGATCCACGAGGGTGAGGGCGTCGCCGCCAAGGCCCTGGAATCCATGGGAA
TCTCCCTGGAGGCCGTCCGTACCGAGGTCGAGGACATCATCGGTACCGGTGGCCACCCGCCGAGCGGCTACATCCCCTTC
ACCCCGCGTGCGAAGAAGGTGCTGGAGCTCGCCCTGCGCGAGGCTCTGCAGCTCGGACACAAGTACATCGGAACCGAGCA
CATCCTGCTCGGTCTGATCCGCGAGGGTGAGGGCGTCGCCGCCCAGGTCCTGGTCAAGCTCGGTGCTGACCTGTCCCGCG
TCCGCCAGCAGGTCATTCAGCTGCTGTCCGGTTACGAGGGTGGCGAGCCCGAGAGTGAGCAGGCCTCCGACGAGCCGGCA
GGTGCCGGTGTCGGTCCCGGCGACGGTGCCCCGTCCGCTCCGAGCGGCAAGCCCGGTCAGAAGTCGAACTCCCTGGTCCT
CGACCAGTTCGGCCGCAACCTGACCCAGGCTGCCAAGGACGGCAAGCTTGATCCGGTGGTCGGTCGCGGCAAGGAGATCG
AGCGCATCATGCAGGTGCTCTCACGCCGTACCAAGAACAACCCGGTGCTCATCGGCGAGCCCGGCGTCGGTAAGACGGCC
GTCGTCGAGGGCCTGGCCCTCGACATCGTCAACGGCAAGGTCCCCGAGACCCTGAAGGACAAGCAGCTCTACTCGCTGGA
CCTCGGTTCCCTCGTCGCCGGTTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAAGGTGCTCAAGGAGATCAACC
AGCGCGGTGACATCATCCTGTTCATCGACGAGATCCACACCCTCGTCGGTGCGGGTGCCGCTGAGGGTGCGATCGACGCC
GCCAGCATTCTCAAGCCGAAGCTGGCCCGTGGTGAGCTGCAGACCATCGGCGCCACCACGCTCGACGAGTACCGCAAGCA
CATCGAGAAGGACGCTGCCCTCGAGCGTCGTTTCCAGCCCGTCCAGGTGCCGGAGCCGAGCGTCGAGATGACCGTCGAGA
TCCTCAAGGGTCTGCGCGACCGCTACGAGGCGCACCACCGTGTGTCCATCACCGACGGTGCGCTCGCCGCCGCCGCGCGT
CTGTCCGACCGGTACATCAACGACCGTTTCCTACCGGACAAGGCCGTCGACCTCATCGACGAAGCCGGCGCCCGTATGCG
TATCAGGCGGATGACCGCGCCGAAGGCGATCCAGGACGTCGACGACAAGATCGCCGAGGTCCGTCGGGCCAAGGAAGCCG
CGATCGACGACCAGGACTTCGAGAAGGCAGCGTCCCTGCGCGACGACGAGCGTCAGCTCTCCGAGGAGCGCGCCGAGAAG
GAGAAGCAGTGGCGCGCCGGTGAACTCGACGACGTCGCCGAGATCGGTGAGCAGGAGATCGCCGAGGTTCTCGGTGCCTG
GACCGGTATCCCCGTCGTCCAGCTCACCGAGGAGGAGACCACCCGTCTGCTCCACATGGAGGACGAGCTGCACGAGCGGA
TCATCGGACAGGAGGACGCCGTCAAGGCGGTCTCCCGCGCGATCCGCCGTACCCGTGCCGGCCTGAAGGACCCGAAGCGT
CCCTCCGGTTCCTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACGGAGCTGTCCAAAGCGCTCGCCGAGTTCCTCTT
CGGCGACGAGGATTCGCTCATCTCCATCGACATGGGTGAGTTCCACGACAAGTTCACGGCGTCCCGCCTCTTCGGCGCTC
CCCCCGGATACGTCGGTTACGACGAGGGTGGCCAGCTCACCGAGAAGGTGCGCCGCAAGCCGTTCTCCGTGGTCCTGTTC
GACGAGATCGAGAAGGCTCACTCCGAGATCTACAACACCCTGCTGCAGGTGCTCGAGGAAGGCCGTCTCACCGACGGTCA
GGGTCGGGTCGTGGACTTCAAGAACACGGTTTTGATCTTCACCTCGAATCTCGGCACGAGGGACATCTCGAAGGCCGTCG
GCATGGGCTTCTCCTCGACCGGCGAGTCGGATGAGAAGGGTCAGTACGACCGGATGAAGTCGAAAGTCAACGACGAGCTG
AAGAAGCACTTCCGCCCGGAGTTCCTCAACCGTATCGACGACATCGTGGTCTTCCACCAGCTCACCCAGGCACAGATCGT
CGAGATGGTCGACCTGCTGCTCGGTCGGCTGCGTAAGGCACTGTCCGACAAGGACATGGCCCTGGAGGTGTCCGACAAGG
CGAAGGACCTGCTGGCCAAGCGTGGCTTCGACCCGGTGCTCGGTGCCCGCCCGCTGCGTCGCACGATCCAGCGCGAGATC
GAGGACCACCTGTCCGAGGAGATCCTCTTCGGCAACGTGGCCTCCGGCGAGATCGTCACCGTCGACGTAGACAACTGGGA
CGGCGGCCCCCGGACCGAGGGTGCGACCTTCGTCTTCGGGTCCAGGCCGAAGCCGGCTCCGGTCGTCATCCCCGAAGTCG
AGGACGAGGCCGAGACCGCCGACGCCACGGCGGATGCCGGTGCCGACACCGGCGACGCCCAGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARALNHNYIGTEHILLGLIHEGEGVAAKALESMGISLEAVRTEVEDIIGTGGHPPSGYIPF
TPRAKKVLELALREALQLGHKYIGTEHILLGLIREGEGVAAQVLVKLGADLSRVRQQVIQLLSGYEGGEPESEQASDEPA
GAGVGPGDGAPSAPSGKPGQKSNSLVLDQFGRNLTQAAKDGKLDPVVGRGKEIERIMQVLSRRTKNNPVLIGEPGVGKTA
VVEGLALDIVNGKVPETLKDKQLYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAIDA
ASILKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVEMTVEILKGLRDRYEAHHRVSITDGALAAAAR
LSDRYINDRFLPDKAVDLIDEAGARMRIRRMTAPKAIQDVDDKIAEVRRAKEAAIDDQDFEKAASLRDDERQLSEERAEK
EKQWRAGELDDVAEIGEQEIAEVLGAWTGIPVVQLTEEETTRLLHMEDELHERIIGQEDAVKAVSRAIRRTRAGLKDPKR
PSGSFIFAGPSGVGKTELSKALAEFLFGDEDSLISIDMGEFHDKFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLF
DEIEKAHSEIYNTLLQVLEEGRLTDGQGRVVDFKNTVLIFTSNLGTRDISKAVGMGFSSTGESDEKGQYDRMKSKVNDEL
KKHFRPEFLNRIDDIVVFHQLTQAQIVEMVDLLLGRLRKALSDKDMALEVSDKAKDLLAKRGFDPVLGARPLRRTIQREI
EDHLSEEILFGNVASGEIVTVDVDNWDGGPRTEGATFVFGSRPKPAPVVIPEVEDEAETADATADAGADTGDAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 86

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB2 YP_004758928.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 58
clpB2 YP_004758928.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 7e-152 51
clpB2 YP_004758928.1 ATP-dependent Clp protease ATP-binding subunit VFG2084 Protein 1e-98 42