Gene Information

Name : clpB1 (CVAR_0381)
Accession : YP_004758802.1
Strain : Corynebacterium variabile DSM 44702
Genome accession: NC_015859
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : 3.4.21.92
Position : 452043 - 454613 bp
Length : 2571 bp
Strand : +
Note : ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGAGCAGTTTCACCCCCACCACCCGTACCCAGGAGGCCATGCAGGCCGCACTGCAGTCTGCCTCGGCGAAGGGCAATCC
GGACATCCGGCCCGCCCACCTGCTGGTCGCGATCCTCGAGCAGGAGGATTCCATCGCCCGCCCGGTCCTCCAGGCTGCCG
GTGTGGACGCTGACGGCGTCCTCGCCGACGCCCGCGACCTCGTCGCCGGCTACGCCACCGCCGCCGGCGACGGCCTGGCC
AACCCGAACTTCAACCGGGACGCACTCAACGCCCTGACCGCGGCCCAGGAACTCGCCGCCGAACTCGGCGACACCTACGT
CTCCACCGAGGTACTGCTCGCCGGTATCGCCAAGGGTTCCGGGGACGCCGCCGAGGCGCTGCAGAACCGTGGCGGCACCT
TCGAGGCCGTCCGCGGCGCCTTCGAGTCCGTCCGTGGCAACCGCAAGGTCACCACCGAGGAGCCCGAAGGCCAGTTCCAG
GCCCTGGAGAAGTACTCCACCGACCTCACCGCCCGCGCCCGCGAAGGCAAGATCGACCCGGTCATCGGCCGCGACCAGGA
GATCCGTCGCGTCGTCCAGGTGCTGAGCCGCCGCACGAAGAACAACCCGGTCCTCATCGGCGAGCCCGGCGTCGGCAAGA
CCGCCATTGTTGAAGGCCTCGCCCGCCGTATCGTCGCCGGCGACGTGCCCGAGTCGCTGCGCGGCAAGAAGCTCATCTCC
CTCGACCTCGGTTCCATGGTCGCCGGTGCGAAGTACCGCGGTGAGTTCGAGGAACGCCTCAAGGCCGTCCTCGACGAGAT
CAAGGAGGCCGAGGGCGAGGTCATCACCTTCATCGACGAGCTGCACACCATCGTCGGTGCCGGTGCCACCGGTGATTCCG
CGATGGACGCCGGCAACATGATCAAGCCGCTGCTCGCCCGTGGTGAGCTGCGCCTGGTCGGTGCGACCACCCTCGACGAG
TACCGGAAGTACATCGAGAAGGACGCCGCCCTGGAGCGTCGTTTCCAGCAGGTCTACGTCGGTGAGCCGACGGTGGAGGA
CACCATCGGTATCCTCCGTGGTCTCAAGGAGCGCTACGAGGTCCACCACGGCGTCCGGATCCAGGACTCCGCCCTGGTCG
CCGCCGCGACCCTGTCCGACCGCTACATCACCAGCCGTTTCCTGCCGGACAAGGCCATCGACCTCGTCGATGAGGCCGGG
TCCCGGCTGCGCATGGAGATCGACTCCCGCCCGGAAGAGATCGACGACGCCGAGCGCATCGTCCGTCGCCTCGAGATCGA
GGAGATGGCGCTGAGCCAGGAGACCGATGACGCGTCCAAGGACCGTCTCGAGAAGCTGCGCGCAGAGCTGGAGGACGAGC
GTGAGAAGCTCTCCGGACTCACCGCGCGCTGGGAGAACGAGAAGGGCTCCATCGACGCGGTCCGCTCCCTCAAGGAGGAA
CTGGATTCGCTGAAGACCGAGTCTGAGATCGCCGAGCGAGACGGGGACTACGCCCGTGTCGCCGAGCTGCGCTACGGCCG
GATCCCGGAACTGGAGAAGGAGCTCGCCGGAGCCGAGGCGTCCGCCGCCAAGGCCGAGGAGGAGCGCATGCTCACCGAGG
AGGTCACCCCGGACACCATCGCCGAGGTCGTCGCCGCCTGGACGGGCATCCCCGCCGGCAAGATGCTGCAGGGCGAGACC
GAGAAACTGCTCGCCATGGAGCAGGTGCTGGGTGGCCGCGTCGTCGGTCAGAAGGACGCCGTCACCGCGGTCTCCGACGC
GGTGCGTCGTTCCCGGGCCGGTGTCGCCGACCCGGACCGGCCGACCGGTTCCTTCCTCTTCCTGGGGCCGACCGGTGTCG
GTAAGACCGAGCTGGCGAAGTCGCTGGCGGAGTTCCTCTTCGACGACGACCACGCCATGGTCCGCATTGACATGTCCGAG
TACGGCGAGAAGCACTCTGTGGCGCGTCTCGTCGGTGCTCCCCCCGGATACGTCGGCTACGACGCCGGTGGACAGCTCAC
CGAGGCCGTGCGGCGCCGCCCGTACACCGTGGTGCTGTTCGACGAGGTCGAGAAGGCGCACCCGGATGTCTTCGACGTAC
TGCTGCAGGTCCTCGACGAAGGACGCCTGACCGACGGCCAGGGCCGGACCGTGGACTTCCGCAACACGATCCTGATCCTC
ACCTCGAACCTCGGTGCCGGTGGCACGGATGAGCAGGTGATGGACGCGGTGAAGCACGCCTTCAAGCCGGAGTTCATCAA
CCGTCTCGACGACGTGGTCATCTTCGAGTCCCTGTCCGCCGAACAGCTGAAGTCCATCGTGGAGATCCAGGTCCGTCAGC
TCGCCGAGCGGCTGGCCGCCCGTCGCCTGGACCTGCAGGTCACCGAGGCTGCGAAGAGCTGGTTGGCTGAGCGTGGTTAC
GAGCCGGCCTACGGTGCCCGCCCGCTGCGTCGCCTGATCCAGAAGGCGATCGGGGACGCACTGGCGAAGAAGCTGCTCGC
CGGTGAGGTCCGCGACGGCGACACGGTGCAGGTCGATGTGGACCCGCACCTCGATTCCCTGGTCATCGAGGCTGTCGCCC
ACGAGGACTGA

Protein sequence :
MSSFTPTTRTQEAMQAALQSASAKGNPDIRPAHLLVAILEQEDSIARPVLQAAGVDADGVLADARDLVAGYATAAGDGLA
NPNFNRDALNALTAAQELAAELGDTYVSTEVLLAGIAKGSGDAAEALQNRGGTFEAVRGAFESVRGNRKVTTEEPEGQFQ
ALEKYSTDLTARAREGKIDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLRGKKLIS
LDLGSMVAGAKYRGEFEERLKAVLDEIKEAEGEVITFIDELHTIVGAGATGDSAMDAGNMIKPLLARGELRLVGATTLDE
YRKYIEKDAALERRFQQVYVGEPTVEDTIGILRGLKERYEVHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAG
SRLRMEIDSRPEEIDDAERIVRRLEIEEMALSQETDDASKDRLEKLRAELEDEREKLSGLTARWENEKGSIDAVRSLKEE
LDSLKTESEIAERDGDYARVAELRYGRIPELEKELAGAEASAAKAEEERMLTEEVTPDTIAEVVAAWTGIPAGKMLQGET
EKLLAMEQVLGGRVVGQKDAVTAVSDAVRRSRAGVADPDRPTGSFLFLGPTGVGKTELAKSLAEFLFDDDHAMVRIDMSE
YGEKHSVARLVGAPPGYVGYDAGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILIL
TSNLGAGGTDEQVMDAVKHAFKPEFINRLDDVVIFESLSAEQLKSIVEIQVRQLAERLAARRLDLQVTEAAKSWLAERGY
EPAYGARPLRRLIQKAIGDALAKKLLAGEVRDGDTVQVDVDPHLDSLVIEAVAHED

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-100 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB1 YP_004758802.1 ATP-dependent Clp protease ATP-binding subunit VFG2084 Protein 8e-112 44