Gene Information

Name : ureC (CVAR_2593)
Accession : YP_004761009.1
Strain : Corynebacterium variabile DSM 44702
Genome accession: NC_015859
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 2922014 - 2923741 bp
Length : 1728 bp
Strand : -
Note : Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAGCTCGATCGACCGACACCGCTACCAGGAGATCTACGGCCCCACCACCGGGGACACCGTCCGGCTGGCGGACACCGA
CCTCACCGTACGCATCACCCGTGACTTCCTGGCGGACGCCTACGGCGACGAGTCCGTCTACGGCGGCGGCAAGGCTGTGC
GCGACGGCATGGCCCAGGACCCCACCGCCACCGCGGCGACCGGCGCGCTCGACACCGTCATCACCGGCGTCATCGTGCTC
GACGCCGTCGCGGGCGTGGTCAAGGGTGATGTCGGCATCCGCGACGGCCGCATCGTGAAGATCGGCAAGGCCGGCAACCC
GAACACCCAGGACGGCGTGGACCCGGAGCTGGTCATGGGGCCAGGTACCGAGGTCATCGCCGGTGAACACCGCGTCCTCA
CCGCGGGTGGGGTGGACTCCCACATCCACTACATCACCCCGCAGCAGGCAGAACACGGCCTCGCCGGCGGCATCACCACC
TTCTTCGGCGGCGGGACCGGACCGGCCGAGGGGACGCTCGGCACGACCTGCACCCCGGGCCCGAACGGCGTGCAGTTCAT
GCTGCGTGCCGCCGAGGGCATGCCGGTGAACACCGGCTTCCTCGGCAAGGGCTCCGGAGCCCTGCCCGAGGCGCTGGCCG
AGCAGATCGTCGGCGGTGCCGCAGGCCTGAAGATCCACGAGGACTGGGGTGCGACCCCGGCGAACATCCGCAACGCCATG
GACGTCTGCGACGAGTACGACGTGCAGCTCGCCATCCACACCGACACCCTCAACGAGGGCGGCTTCTTCGAGTCCACGGC
CCGGGCCTTCGGCGGACGCACCGTCCACACCTTCCACTCCGAGGGCGCCGGCGGGGGTCACGCCCCGGACATCCTCCGGG
TCTCCGGCATGCCGAATGTGCTGCCCGCCTCCACCAACCCGACGCTGCCGTACACCGTGAACTCGGTGGAGGAACTGCTG
GACATGGTGATGGTCTGCCACCACCTGTCCCACGACATCCCCGAGGACGTCGCCTTCGCCGACTCACGCGTGCGCGCCGA
GACCATCGCGGCGGAGACGGTCTTCCACGATCTGGGCCTGATCAGCATCTTCAGTTCCGACTCACAGGCGATGGGACGCG
TCGGCGAGTCCTGGCAGCGCGCCTTCCAGACCGCCCACCACTGCAAGGTGGAGCTCGGTGAGCTGGAGGAGGACAAGGGC
CACGGTGACGACAACGAGCGCGTCCTACGCTACGTCGCGAAGATCACGGTCAATCCGGCGATCGCCCAGGGAATCGGTGA
GCACGTCGGCAGTATCGAGCCCGGAAAGCTCGCCGACCTGGTGCTCTGGCCGGTGGAGACCTTCGGCGCGAAGCCCCGGC
TGGTGCTGCGCCAGGGACGCATCGCCTACGCCCAGATGGGTGACCCGAACGCCTCGCTGGCCACCCCGCAGCCGGTCTAC
TACCGCGACATGTTCGCCAACTACGGCACCGCACTGCAGGCCACCCGTGTGACCTTCATGAGCCAGGCCGCGATCGAGGC
CGGCGTCCCGGAGCAGCTGGGCCTGACCTCGACCGTTCTGCCGGTGAAGAACACCCGCACCATCGGCAAGAAGGACATGG
TGCGCAACAACCGTACCGCCGACATCCGCGTCGACCCGGACACCTACGAGGTCTCCGTCGACGGCGTCCACGCGACCATC
GCCCCGGCGGAGTCCCTGCCGCTGGCGCAGAAGTTCTTCCTGTTCTGA

Protein sequence :
MSSIDRHRYQEIYGPTTGDTVRLADTDLTVRITRDFLADAYGDESVYGGGKAVRDGMAQDPTATAATGALDTVITGVIVL
DAVAGVVKGDVGIRDGRIVKIGKAGNPNTQDGVDPELVMGPGTEVIAGEHRVLTAGGVDSHIHYITPQQAEHGLAGGITT
FFGGGTGPAEGTLGTTCTPGPNGVQFMLRAAEGMPVNTGFLGKGSGALPEALAEQIVGGAAGLKIHEDWGATPANIRNAM
DVCDEYDVQLAIHTDTLNEGGFFESTARAFGGRTVHTFHSEGAGGGHAPDILRVSGMPNVLPASTNPTLPYTVNSVEELL
DMVMVCHHLSHDIPEDVAFADSRVRAETIAAETVFHDLGLISIFSSDSQAMGRVGESWQRAFQTAHHCKVELGELEEDKG
HGDDNERVLRYVAKITVNPAIAQGIGEHVGSIEPGKLADLVLWPVETFGAKPRLVLRQGRIAYAQMGDPNASLATPQPVY
YRDMFANYGTALQATRVTFMSQAAIEAGVPEQLGLTSTVLPVKNTRTIGKKDMVRNNRTADIRVDPDTYEVSVDGVHATI
APAESLPLAQKFFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 6e-136 57
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 6e-136 57
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-134 55
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-134 55
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 7e-134 55
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 7e-134 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_004761009.1 urease subunit alpha VFG0270 Protein 2e-131 56