Gene Information

Name : entE1 (CVAR_2384)
Accession : YP_004760802.1
Strain : Corynebacterium variabile DSM 44702
Genome accession: NC_015859
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 2689377 - 2690819 bp
Length : 1443 bp
Strand : +
Note : Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

DNA sequence : 
GTGACCTGGTATGACCTGGACGCGGGAGTCTCCCGTGCCGCCGCCGTCCTGGCCGGCGCCGGGGTCGGACGCGGTGACGG
CGTCATCATCCAGCTGCCGAACTCCGTGGCCTACCTGGAGACCGTCTTCGCCGTCTGGCGGCTCGGCGCGATCCCGGTCT
TCTCCCCGCCCGCCCACGGCTCCGCCGAGATCCGCCACTTCGCCTCCCACGCCCCGGCCCGGTTCTACGTCTCCACCGGG
ACCCCGAACCGGCACCTCGCCCGGGTGCACAGGGACATTGCCGACCTCGCCGGCACCGTCACCATGATCCTCGTCGACGA
GGCGTCCCCGTGGGACGGGGCGGACGCCCTCCCCGTGCCGGACGCCGCGTCCGTCCCCTCCGAGAAACTCGCTTTCCTGC
AGCTCTCCGGCGGGACGACCGGTGTGCCGAAGCAGATCCCGAAGACCCATGACGACTACCTCTACTCGGTGCGCGCCTCC
GTCGACGTCTGCGATCTGCGGCACGGCGATGTGCTGCTCGTGGCTCTGCCCGCCTCCCACTACTTCACGATGAGCTCCCC
GGGGATCCTCGGTGCGGTGCAGGTCGGGGCGTCCATCGTCTTCGCCGCCGACCCGATGCCGACCGAGGTGCTCCCGCTGA
TCGCCGAACACGGCGTCACCCATCTGGCCCTGGTGCCGCCGGCGCTGATCAGTCTGCTGAACTTCCCCGGGCGCGACGCC
TACGACGTGTCCTCGGTACGCACCGTCTGGGTCGGCGGGGCGAAGCTGTCCGAGGCTGCGGCGCGGCGCGTCCGCCCGGA
GCTCGGTTGGACGCTCCAGCAGGTCTTCGGCATGGCCGAGGGTCTGGTCAACTACACCCCGCTGGACGCCTCGATCGAGG
AGATCGTCTCCACACAGGGCCGCCCGATGAGTCCGTGGGACGAGATCCGCGTCGTCGATGACGAGGACGTCGACGTGCCG
GAGGGTGAGCCGGGCAACCTGCTGACCCGCGGTCCGTACACCATCCGCCGCTACCACCGCGCCCCCGAGGTCAACGCCCG
GTCGTTCACCGAGGACGGCTTCTACCGCACCGGCGACATCGTCGTCTTCCGCGAGGGGACGCTGACCGTCGTCGGACGTG
CCAAGGACCAGATCAACCGGGGTGGCGAGAAGATCGCGCCGGAGGCCGTGGAGAACATCCTGCTCACCCATGACGCCGTC
CACGACGTCTCTGTCATCGGCGTGCCGGACGAGGTGCTCGGTGAGAAGATCCGCGCCTTCGTCATCCCCCGGCAGGACGC
CGCCTCCGACCCCGCCGCCCACGGGCTGACCCCCACGAAGCTGCGGAAGTTCGCCCGCGAGGCCGGCTTATCGAGCTTCG
CGGTGCCGGACCTCATCGACATCGTCGCCGAGTTCCCGCTCACCGGTGTCGGCAAGGTCTCGAAGAAGGCACAGCAGGGG
TAG

Protein sequence : 
MTWYDLDAGVSRAAAVLAGAGVGRGDGVIIQLPNSVAYLETVFAVWRLGAIPVFSPPAHGSAEIRHFASHAPARFYVSTG
TPNRHLARVHRDIADLAGTVTMILVDEASPWDGADALPVPDAASVPSEKLAFLQLSGGTTGVPKQIPKTHDDYLYSVRAS
VDVCDLRHGDVLLVALPASHYFTMSSPGILGAVQVGASIVFAADPMPTEVLPLIAEHGVTHLALVPPALISLLNFPGRDA
YDVSSVRTVWVGGAKLSEAAARRVRPELGWTLQQVFGMAEGLVNYTPLDASIEEIVSTQGRPMSPWDEIRVVDDEDVDVP
EGEPGNLLTRGPYTIRRYHRAPEVNARSFTEDGFYRTGDIVVFREGTLTVVGRAKDQINRGGEKIAPEAVENILLTHDAV
HDVSVIGVPDEVLGEKIRAFVIPRQDAASDPAAHGLTPTKLRKFAREAGLSSFAVPDLIDIVAEFPLTGVGKVSKKAQQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-71 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-71 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-71 43
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-71 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-71 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-71 43
ybtE CAA21394.1 - Virulence HPI Protein 3e-71 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-71 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 3e-71 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE1 YP_004760802.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-84 47
entE1 YP_004760802.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 2e-72 43
entE1 YP_004760802.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 6e-65 41