Gene Information

Name : aldA (CVAR_0116)
Accession : YP_004758536.1
Strain : Corynebacterium variabile DSM 44702
Genome accession: NC_015859
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 143426 - 144967 bp
Length : 1542 bp
Strand : +
Note : NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGACCATCACCGCACAGGGCAGCAACGTCTACGCAGCACCCGGCACCGAGGGATCCCTCATCTCGTTCAAGCCCCGCTA
CGGCAACTTCATCGGCGGCCAGTGGGTCGAGCCCGCTGACGGCCAGTACATGGAGAACATCAGCCCCGTCGACGGCAAGG
TCTTCTGCGAGGTCCCCCGCTCGAAGGCCGCGGACGTGGAGAAGGCCCTCGACGCCGCCCACGCCGCCGCACCCGCCTGG
GGGAAGACCAGCGTCCAGGAGCGGTCCCGCATCCTGCTGAAGATCGCCGATGTCCTCGAGGAGAACCTCGAGATGCTCGC
CGTCGCGGAGACCTGGGACAACGGCAAGCCGGTCCGTGAGACCCTCGCCGCCGACCTGCCCCTGGCCGTGGACCACTTCC
GGTACTACGCCGGTGCGCTCCGCGCCCAGGAAGGCCACCTCTCCCAGATCGACGAGAACACCGTCGCCTACCACTTCCAC
GAGCCGCTGGGTGTCGTTGCCCAGATCATCCCCTGGAACTTCCCGATCCTCATGGCGGCGTGGAAGATCTGCCCCGCACT
GGCCGCCGGTAACGCGATCGTCCTCAAGCCGGCCGAGCAGACCCCGGCGTCCATCCTCGTGGTCGCCGAGCTCATCGCCG
ACCTGCTTCCCGACGGCGTCCTCAACATCGTCAATGGCCTCGGCGAGGAGACCGGCGCGGCTCTGACCGCCTCGGACCGC
ATCGCCAAGATCGCCTTCACCGGTTCCACAGAGGTCGGCAAGATCATCAACAAGGCTGTCGCCGAGAAGCTCATCCCGGT
CACCCTGGAGCTCGGCGGCAAGTCCCCGAACATCTTCTTCGGTGACGTCATGGACGCCGACGACTCTTTCCGTCAGAAGA
CCCTCGAGGGCTTCTCGATGTTCGCCCTCAACCAGGGTGAGGTCTGCACCTGCCCGTCCCGCGCACTGGTCCAGGAGTCC
ATTGCCGACGAGTTCCTCGAGCTCGCCGTCGAGCGCGTCCGCCAGGTCAAGGTCGGTAACCCGCTGGATCCCGAGACCAT
GATCGGTGCCCAGGCCTCCCTGGAGCAGATGGACAAGATCTCCAGCTACCTCAAGTCCGGCCCTGAGGAGGGTGCCGAGG
TGCTCATCGGCGGCAGCGTCCGTACCGTCGACGGCCTGGAGAACGGCTTCTACGTCGAGCCGACCGTCCTCAAAGGCAGC
AACAACATGCGTTGCTTCCAGGAGGAGATCTTCGGCCCGGTCCTCGCCGTCACCACCTTCCAGGACTTCGACGACGCCAT
CGCGATCGCCAACGACACCGACTACGGCCTCGGCGCCGGCGTCTGGGCCCGTGACGGCCGGACCGCCTACCAGGCGGGAC
GCGCCATCCAGTCCGGTCGTGTGTGGGTGAACAACTACCACTCCTACCCGGCGCACGCGGCGTTCGGCGGCTACAAGAAG
TCCGGTATCGGTCGCGAGACCCACCTGATGATGCTGGACCACTACCAGCAGACGAAGAACCTGCTCTGGTCCTACGACGA
GAACCCCAACGGTCTCTTCTGA

Protein sequence :
MTITAQGSNVYAAPGTEGSLISFKPRYGNFIGGQWVEPADGQYMENISPVDGKVFCEVPRSKAADVEKALDAAHAAAPAW
GKTSVQERSRILLKIADVLEENLEMLAVAETWDNGKPVRETLAADLPLAVDHFRYYAGALRAQEGHLSQIDENTVAYHFH
EPLGVVAQIIPWNFPILMAAWKICPALAAGNAIVLKPAEQTPASILVVAELIADLLPDGVLNIVNGLGEETGAALTASDR
IAKIAFTGSTEVGKIINKAVAEKLIPVTLELGGKSPNIFFGDVMDADDSFRQKTLEGFSMFALNQGEVCTCPSRALVQES
IADEFLELAVERVRQVKVGNPLDPETMIGAQASLEQMDKISSYLKSGPEEGAEVLIGGSVRTVDGLENGFYVEPTVLKGS
NNMRCFQEEIFGPVLAVTTFQDFDDAIAIANDTDYGLGAGVWARDGRTAYQAGRAIQSGRVWVNNYHSYPAHAAFGGYKK
SGIGRETHLMMLDHYQQTKNLLWSYDENPNGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-132 60
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 8e-141 60
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 8e-141 60
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 8e-141 60
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-140 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_004758536.1 aldehyde dehydrogenase VFG0082 Protein 1e-132 60