Gene Information

Name : entE (BPI_II15)
Accession : YP_004757246.1
Strain :
Genome accession: NC_015858
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.7.7.58
Position : 12099 - 13940 bp
Length : 1842 bp
Strand : -
Note : -

DNA sequence : 
TTGTGCGCCTCTTTGCCGGGGCGGGGATCGTGGAAGCCTCCAGCCCGGATTCCGAATGGGCCGAAGTACAGACCAAGCTT
GGCACCATGCTGCGTGCCTGCGGCCTTTCGGCCTGAAACAGAGCCTCTCCATGTCTTTGTTTCTACGCATTATCCGACGC
AGAGCCGCTTCGCATTGCGGGCTCGAAAACTGCACTCGTTTTTATTTCAAGCAGAACAAGTCATGACCATCGAATTTACC
CATTGGCCACCGGCACGCGAACGCCTCTATCGCGAAAAGGGCTACTGGATCGACAAACCCCTCACCCGCGCACTGGAAGA
ACAGGCCGCCATGCGGCCCGATGCGCCCGCTATCCTCTGCGGCGAGCGGCGTTTCACCTATGCCGAACTCGACCGTCTGT
CTTCCAACCTGGCCTCCCGGCTTGCGGCAGCCGGCATAGGCAAAGGCGACACGGCACTGGTGCAACTGCCCAATATCGCC
GAATTCTACATCGTGTTCTTCGCACTCATGAAAGCGGGCATCGCGCCCGTCAATGCGCTTTTCAGCCATCGCAAGCTGGA
GCTTGGCGCCTATGCCAGCCAGATCGAACCACGGCTGCTGATCGGCTCACGCCAGCATGAACTCTTCATGGATGACGCCT
TTGCCCGCGACCTTGGCAAAAATCTTTCCGCACCGCTGCTAACACTTTTTGCAGGCGAGGCCGACCCTGCGTCGAGCCTC
GACCACTGGATCGCCACGCCTGCGGACAAAGCCGTTCCCTTCTCGCCAACCGGCGCTGGCGAAGTCGCCTTTTTCCAGCT
TTCCGGCGGCAGCACCGGCACGCCGAAACTCATCCCGCGCACGCATAATGATTATGATTACAGCGTGCGCGCCAGCGTGG
AAATCTGCGCGCTGACACCGCAGACCCGTTTTCTCTGCGCCCTGCCCACCGCGCATAATTATCCAATGAGTTCGCCCGGC
GCGCTCGGCGTTTTCCATGCGGGCGGCTGTGTCGTCATGGCCCCCAACCCGGAACCGCTCAACTGCTTCTCCATCATCGA
ACGTCATGGCGTAAACATGGTGGCACTGGTGCCTCCGGCAGTGGCGCTCTGGCTACAGGCAGCCCCCGATCATCTGGCAG
CACTCAGCTCGCTGAAACTCGTGCAGGTGGGTGGCGCAAGCTTTGCGGAGGCGCTTGCCCGGCAGGTGCCACAGGTTCTG
GGCTGCAAGCTGCAACAGGTCTTCGGCATGGCCGAGGGGCTGGTCAACTATACCCGCCTTGACGACCCGGACGAGATCGT
CTTCACCACCCAGGGCCGTCCGATCAGCCCGGACGATGAAATCAGGATCGTCGATGAGGATGGCGAACCCGTGGCCGAAG
GCCAGCCAGGAATGCTGGCCACGCGCGGGCCTTACACGTTCTGCGGCTATTATCGCAGCCCCGAACATAATGCGCAGGTC
TTCGACAGTGAAGGCTTTTATTATTCGGGCGACGTGGTCCAGCGCACGCCGGAAGGCTATCTGCGCGTCGTGGGCCGCGT
GAAGGACCAGATTAATCGCGGCGGCGAGAAAGTTGCCGCCGAGGAGATTGAAAACCTGATCCTCCTCCATCCCGATGTGA
CGCACGCCGCACTTGTCGCCATGCAGGATGAATTGCTGGGCGAGAAAAGCTGCGCTTTCATCGTCTCGCGCAATCCCGAT
CTCAAGCCGCCTGTTCTGCGGCGTCACCTGCTGGCGCTGGGCGTTGCCGAATACAAGCTTCCAGACCGCATCAGGCTCAT
TGAAACCATGCCGCTCACCGCAGTTGGCAAGATCGACAAAAAGCATCTGCGCAAGCTTTCAAGCCCATCCTCCCCCGGTT
AG

Protein sequence : 
MCASLPGRGSWKPPARIPNGPKYRPSLAPCCVPAAFRPETEPLHVFVSTHYPTQSRFALRARKLHSFLFQAEQVMTIEFT
HWPPARERLYREKGYWIDKPLTRALEEQAAMRPDAPAILCGERRFTYAELDRLSSNLASRLAAAGIGKGDTALVQLPNIA
EFYIVFFALMKAGIAPVNALFSHRKLELGAYASQIEPRLLIGSRQHELFMDDAFARDLGKNLSAPLLTLFAGEADPASSL
DHWIATPADKAVPFSPTGAGEVAFFQLSGGSTGTPKLIPRTHNDYDYSVRASVEICALTPQTRFLCALPTAHNYPMSSPG
ALGVFHAGGCVVMAPNPEPLNCFSIIERHGVNMVALVPPAVALWLQAAPDHLAALSSLKLVQVGGASFAEALARQVPQVL
GCKLQQVFGMAEGLVNYTRLDDPDEIVFTTQGRPISPDDEIRIVDEDGEPVAEGQPGMLATRGPYTFCGYYRSPEHNAQV
FDSEGFYYSGDVVQRTPEGYLRVVGRVKDQINRGGEKVAAEEIENLILLHPDVTHAALVAMQDELLGEKSCAFIVSRNPD
LKPPVLRRHLLALGVAEYKLPDRIRLIETMPLTAVGKIDKKHLRKLSSPSSPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 1e-85 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-85 44
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-85 44
ybtE CAA21394.1 - Virulence HPI Protein 1e-85 44
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-86 44
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-85 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 6e-86 44
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-85 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-85 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE YP_004757246.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 2e-143 58
entE YP_004757246.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 1e-106 47
entE YP_004757246.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-87 41