Gene Information

Name : cadA (CFU_1128)
Accession : YP_004751783.1
Strain : Collimonas fungivorans Ter331
Genome accession: NC_015856
Putative virulence/resistance : Resistance
Product : lead, cadmium, zinc and mercury transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1318249 - 1320582 bp
Length : 2334 bp
Strand : +
Note : -

DNA sequence :
ATGCAAGGAGTAATCAATTGCATCTTCAAAACCCGAATCAAGGAGCACATCATGGGCCGTTGCGAACACGACCATAACGA
TCACCAGCATGGTCACGAGCATAAGCACGATCACAAACATGAGCACCAGCATGCGCACGCAGATGCGGGCGCATCCGCCG
CCGGCCGTGCGCCGCTGATTGCAGGGGCGGAACAGGCGGTGTTCCTGATCCAGAAGATGGATTGCCCGACCGAAGAAAAA
CTGATACGCGACAGATTCAGGAACATGGCCGGCATCGAAGCCATGCAGTTCAACCTGATCCAGCGCGAGCTGACGGTCCA
GCATCGCCTGCCTTCGGTGGATGCCATCGTTGCCGCCTTGAAGGCGCTGGACCTGGAGCCGGTGCTCAAATCGGACACGC
TGACCGGCGCCGCCGATCTGACCGCCAGCGACGGCGCTTTCAAGATATCCCGCAGGAAGTGGCTGCTGATGGCGCTTTCC
GGCATGACCGCTGTTGGCGCCGAGGTAGTGGTCTGGAGCGGCGGCCAGGATAGTTCATGGCTGGTGATCGGCCTGGCCCT
GGTAGCGATTCTGAGCGGCGGCCTGGATACCTTGAAAAAGGGCTGGATTGCATTGCGTAATTTTTCCCTCAACATGAATT
TCCTGATGTCGCTGGCGGTGATAGGCGCGGCCATCATCGGCCAATGGCCGGAAGCGGCGGTAGTGATTTTCCTGTTCGCG
CTGGCGGAAATGATCGAGGCCTTGTCGCTGGACCGCGCCCGCAATGCGATCAAAGGGCTGATGGCGATGGCGCCGGACCT
GGCCACGGTGCAAGGCGCCGAGGGCGAGTGGCGCGAGGTCGCCACCGGCGAGGTGGAACTGGCGGCGCTGATCCGCGTCA
AGCCGGGTGCGCGCGTGCCGCTCGATGGCCTGGTGACCGACGGCCAGACCACCATCAACCAGGCCGCGATCACCGGTGAA
AGCATGCCGGTGGAAAAACAGGCCGGCGACCAGGTGTTTGCCGGCACCATCAACGAGCGCGGCTCCTTTGTCTACCGGGT
GACCGCGCTGCAAGCCAATTCGACCCTGGCGCGCATCATCAAGAGCGTGCAGCAGGCGCAGGGCGAGCGCGCGCCGACCC
AGCGTTTCGTTGATCAGTTTGCGCGCTATTACATTCCGGTAGTGGTGCTGGCTGCGTTGCTGGTCGCCACCTTGCCGCCG
CTGCTGATGGGCGCGGAGTTCTATCCGTGGCTGTACAAGGCCCTGGTGCTGTTGGTGATCGCCTGTCCTTGCGCGCTGGT
GATTTCGACGCCGGTGACGGTGGTGAGCGGGCTGGCGGCGGCGGCCAGGAGCGGCGTGCTGGTCAAGGGCGGGGTGTACC
TGGAGATGGGGCGCAAGATCAAGGCGCTGGCGCTGGACAAGACCGGCACGCTGACCTTGGGCAAGCCAGGCGTCACCGAT
GTGCAGCTGGTGCAGCCGGCGGCTGATGACGACCTGCTGCACCAGCTGCAGCGCCAGGCCGCGAGCCTGGCCAGCCGTTC
CGACCATCCGGTGTCGGGCGCGGTAGCGGTGCACTGGCAAACCTTGGCCAATGCCGGAAACCTGTTTGAAGTCGGCGCGT
TTGAAGCGTTGACCGGCCGCGGCGTGCAAGGCAGTATCGACGGCCAGCAATTCTATCTTGGCAATCATCGCCTGGTGCAC
GAGATGGATATCTGCAATCCAGCGCTGGAAGCGCGCCTGTCGGCGCTGGAGAGCGAAGGCAAGACCACCGTGGTGCTGTG
TTCGGCTACCCAACCCTTGCTTATCCTGGCAGTGGCCGATACGGTGCGCGACATTGCAGTCGAAGCAGTCGCCAGGCTGC
AGGCAATCGGAGTCGAAGCTGTCATGCTGACCGGCGACAATGCGCATACCGCGCAGGCCATCGCAACCCAGGTCGGCATC
AGCGACGCCCGCGGCGACCAGCTGCCGCAAGACAAGCGCGACGCCATCAACGACTTGCGCGCGCGTTACGGCTACGTCGG
CATGGTGGGCGACGGCATCAACGATGCGCCGGCGCTGGCGCAAGCCGATATCGGATTTGCGATGGGGGCGGCAGGCAGCG
ACACGGCGCTGGAAACCGCCGACGTGGCGCTGATGGATGACGACTTGCGCAAGATCGCGGACTTCATCCGCTTGAGCAAA
AAGACACACACGGTGCTGATGCAAAACATTACGTTGGCGCTAGGCATCAAAGCCATCTTTCTGGTGCTGGCGCTGACCGG
CGAAGCCACCCTGTGGATGGCGGTGTTCGCCGACATGGGAGCGAGCTTGCTGGTAGTGTTTAACGGCCTGAGGTTGCTGC
GGGCATTGCGCTGA

Protein sequence :
MQGVINCIFKTRIKEHIMGRCEHDHNDHQHGHEHKHDHKHEHQHAHADAGASAAGRAPLIAGAEQAVFLIQKMDCPTEEK
LIRDRFRNMAGIEAMQFNLIQRELTVQHRLPSVDAIVAALKALDLEPVLKSDTLTGAADLTASDGAFKISRRKWLLMALS
GMTAVGAEVVVWSGGQDSSWLVIGLALVAILSGGLDTLKKGWIALRNFSLNMNFLMSLAVIGAAIIGQWPEAAVVIFLFA
LAEMIEALSLDRARNAIKGLMAMAPDLATVQGAEGEWREVATGEVELAALIRVKPGARVPLDGLVTDGQTTINQAAITGE
SMPVEKQAGDQVFAGTINERGSFVYRVTALQANSTLARIIKSVQQAQGERAPTQRFVDQFARYYIPVVVLAALLVATLPP
LLMGAEFYPWLYKALVLLVIACPCALVISTPVTVVSGLAAAARSGVLVKGGVYLEMGRKIKALALDKTGTLTLGKPGVTD
VQLVQPAADDDLLHQLQRQAASLASRSDHPVSGAVAVHWQTLANAGNLFEVGAFEALTGRGVQGSIDGQQFYLGNHRLVH
EMDICNPALEARLSALESEGKTTVVLCSATQPLLILAVADTVRDIAVEAVARLQAIGVEAVMLTGDNAHTAQAIATQVGI
SDARGDQLPQDKRDAINDLRARYGYVGMVGDGINDAPALAQADIGFAMGAAGSDTALETADVALMDDDLRKIADFIRLSK
KTHTVLMQNITLALGIKAIFLVLALTGEATLWMAVFADMGASLLVVFNGLRLLRALR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 61
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-118 45
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-120 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-118 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_004751783.1 lead, cadmium, zinc and mercury transporting ATPase BAC0298 Protein 0.0 60
cadA YP_004751783.1 lead, cadmium, zinc and mercury transporting ATPase BAC0092 Protein 2e-86 42
cadA YP_004751783.1 lead, cadmium, zinc and mercury transporting ATPase BAC0461 Protein 8e-78 41