Gene Information

Name : Atc_1726 (Atc_1726)
Accession : YP_004749075.1
Strain : Acidithiobacillus caldus SM-1
Genome accession: NC_015850
Putative virulence/resistance : Resistance
Product : Mercuric ion reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1779458 - 1781074 bp
Length : 1617 bp
Strand : +
Note : -

DNA sequence : 
ATGACCCAAAATCTCGATCTCGGCATCACCGGAATGACCTGCGAGCATTGCGCCCGCACGGTGGAAAAAGCTTTGCGTGC
GGTCCCCGGCGTCCTTGCGGCGGAGGTCTCCTGGCCAGAACGCCGGGCACGCATCCAGGCCAGCGCAGATCTCGACCCGG
CTGCCCTGGGCCGCGCCGTCACGGCCGCCGGTTACGGTATCGGCGATGGCGACTATCACGGCGGGAGTCTGCACGTCGCC
ATCATCGGCTCCGGTTCCGCCGCTTTCGCCGCCGCCCTCCGCTTGGTGGAAGGGGGCGCGCGGGTCACCATGATCGAGGC
CGGCACCTTGGGGGGCACCTGCGTCAATGTCGGTTGTGTGCCTTCCAAAATCTTCATTCGCGCGGCGCAAACCGCCCACA
TCCTGCAAGCGCATCCCGTCGCCGGCTTGGAGCATCATCGATCCCGTGTCGATCGCCGCGCCATGCAGGCGCAGCAGCAG
GCACGCGTGGAGGCCCTGCGCCAGGCGAAGTATCAGCGGGTTCTGGAGGTCCATCCGCAAATCACCCTGCGCCGGGGACG
CGCCCGCTTCCTCGACAGACAACACCTGGAGATCGCTGACGGCAGTGGCAGAAAAGACGTCGTCAGCGCCGACCGCGTGC
TCATCGCCACGGGCTCGCGTCCTGCCATTCCGCCCATTCGGGGTCTCGACCAGACTCCCTACTGGACCTCTACCGAGGCG
CTGGCTGCAACCGAGATTCCCCGGCGTTTGCTGGTCATCGGCGCTTCCATCGTTGCCCTGGAACTGGCGCAGGCCTTTGC
GCGCCTCGGCAGCAGCGTTACCATCCTCGCACGCAGCACCCTGCTGTCGCAACTGGATTCAGAAATCGGAAAAGCGCTCA
AGACCATACTCGAGGGCGAGGGTCTGGATATCCGCCTGCACAGCCAGCCCGATAGCGTCCACTACCGCGATGGCCAGTTC
CACACCCGGCTCGGCGAAGCGGACCTGATCAGCGATGCCCTCCTGGTGGCCACGGGCCGACGCGCCAATACCGACGATCT
CGGACTGGAAGCGCTCGGCGTGGCCTGCAACGCCCAGGGCGCCATCGCCGTCGATAGCGCAATGCGCTCCACCGTTGCGG
GGATCTTTGCTGCTGGCGATTGCAGCACCCTACCACAATACGTCTACGTAGCGGCCGCCGCCGGCACCCGGGCAGCGGTC
AATATGCTCGGTGGCGATGCTCAGCTGGATCTCGCGGTATTGCCGGCGGTGGTCTTCACCGATCCTCAGGTGGCCACCGT
CGGGCTGGATGAGAAAGCCGCCCGCGCCGCAGGGCATCGAGTAACGGTGCGCCGTCTGAATCTGGATCAGGTGCCCCGCG
CTCTGGCCAATTTCGACACTCGCGGTTTCATCAAGATGGTGGCCGATGCCGACACGGATCGCCTCTTGGGCGTACAGGTT
TTGGCCGCCGAAGGCGGCGAGCTCATTCAGACCGCCGCCGTCGCTCTGCGGGCGGGCTGGCGGATCGAAGACCTTGCCAG
CATGCTCTTTCCCTATCTGACTATGGTGGAGGGGCTCAAGCTGTGCGCCCAGACCTTCACCAAAGATGTCTCGGAACTCT
CCTGCTGCGCCGGCTGA

Protein sequence : 
MTQNLDLGITGMTCEHCARTVEKALRAVPGVLAAEVSWPERRARIQASADLDPAALGRAVTAAGYGIGDGDYHGGSLHVA
IIGSGSAAFAAALRLVEGGARVTMIEAGTLGGTCVNVGCVPSKIFIRAAQTAHILQAHPVAGLEHHRSRVDRRAMQAQQQ
ARVEALRQAKYQRVLEVHPQITLRRGRARFLDRQHLEIADGSGRKDVVSADRVLIATGSRPAIPPIRGLDQTPYWTSTEA
LAATEIPRRLLVIGASIVALELAQAFARLGSSVTILARSTLLSQLDSEIGKALKTILEGEGLDIRLHSQPDSVHYRDGQF
HTRLGEADLISDALLVATGRRANTDDLGLEALGVACNAQGAIAVDSAMRSTVAGIFAAGDCSTLPQYVYVAAAAGTRAAV
NMLGGDAQLDLAVLPAVVFTDPQVATVGLDEKAARAAGHRVTVRRLNLDQVPRALANFDTRGFIKMVADADTDRLLGVQV
LAAEGGELIQTAAVALRAGWRIEDLASMLFPYLTMVEGLKLCAQTFTKDVSELSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 8e-116 56
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 4e-116 55
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 6e-116 55
merA AFG30120.1 MerA Not tested PAGI-2 Protein 4e-116 55
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-114 55
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-114 55
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-114 55
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 7e-111 54
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 9e-111 54
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 4e-108 53
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 5e-73 41
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 7e-73 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Atc_1726 YP_004749075.1 Mercuric ion reductase BAC0652 Protein 9e-108 58
Atc_1726 YP_004749075.1 Mercuric ion reductase BAC0653 Protein 1e-114 54
Atc_1726 YP_004749075.1 Mercuric ion reductase BAC0650 Protein 2e-112 54
Atc_1726 YP_004749075.1 Mercuric ion reductase BAC0651 Protein 3e-73 41
Atc_1726 YP_004749075.1 Mercuric ion reductase BAC0224 Protein 1e-71 41