Gene Information

Name : Atc_1058 (Atc_1058)
Accession : YP_004748407.1
Strain : Acidithiobacillus caldus SM-1
Genome accession: NC_015850
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1056887 - 1058551 bp
Length : 1665 bp
Strand : -
Note : -

DNA sequence : 
ATGACTAAGAACATCGCATTGGATATCCTGGGCATGACCTGCGAGCACTGTGCCGTAACGGTCCAAAAAGCCCTTCGCAA
CGTGCCTGGAGTACAGGACGCCCGCGTGTCCTTTTCGCAAGGCCAGGCAAACATCGATCTTGCAGTCGACGTCCCCACGC
GCGATCTCATCGCTGCCGTTAACTTGGTGGGGTATGGCGCAGTGGCTCCTGGTGAATCCGGCCCGAAAATGGGACAGATT
CCGACGGGCGCGCAGCCCAGGTCCAGTTCGGACGGGATGCGGATCGTTATTATTGGGTCGGGTTCCGCCGCCTTTGCTGC
CGCCATCCGCGCGGTGGAGGAAGGCGCCCGCGTGACCATGATCGAAAAGGGCACGCTCGGAGGAACCTGCGTCAACATCG
GTTGCGTGCCCTCAAAGATCCTCATTCGTGCGGCCCAAATGGCTCACGAGCAGAGGGCGCATCCTTTTGAGGGCTTGGCG
CACGCAACCCCAGCGGTGGACCGTACCGCCCTGGTCGCTCAGCAGCAGCACCGGGTCGAGGAACTGCGCCAGGAGAAATA
TGCCAATGTCTTGACCGCGTACCCCGCCATTACGTTCCTGCAGGGAACCGCACGCTTTGTCGATTCCCACTCCGTGGCCG
TTCAATCCGCAGATGGCACAGAGCAGACGGTTCAAGGGGATCGTTTTCTTATCGCCGTCGGTGCGCGTCCCCATGTACCG
GGGATTCCGGGCATCGCCCAGACGCCCTACTGGACGTCCACCGAAGCTTTGGTCGCCACCGAACTTCCCCAACACCTGAT
CGTCTTGGGTGGATCGGTGGTCGCGGTGGAAATGGCTCAAGCCTTTCGGCGACTCGGTGCGCAGGTGACGGTACTGGCAC
GCAGTACACTCCTGTCGCGGGAGGACCCAGCGCTCGGTGAAGGGCTCAAGGCAGCTTTCGAGGCCGAGGGCATCCGTGTC
CTGCTGCACACGACCCCCAAATCGGTCCGCTACGAGCGCGATACGTTCCTGGTGGAAACTGCTACCGAAACCTTACGCGG
CGATCGATTGCTGGTAGCTACGGGACGCACACCCAACACCGACCAGCTTGGTCTCGAGACCATTGGGGTGATTACGGCCG
ATTCTGGTGCCATTGTGGTCGACGATCACATGCAAACCAGTGTGTCTCACATCTTTGCCGCTGGAGATTGCACGACCCTT
CCGCAGTTCGTCTATGTCGCTGCCGCCGGCGGTACCCGGGCCGCCATCAACATGATGGGTGGCGACGCCGTGCTCGATTT
ACAGACCATGCCCGCGGTGGTCTTTACCGATCCGCAGGTGGCCACCGTCGGGTTAGACGCGCGTTCGGCTGAGCGCCTCG
GCATCCGGGCGATCAGCCGCACCCTCACCCTGGACAATGTCCCCCGTGCACTGGCCAACTTCGACACGAGGGGGTTCATC
ACCCTGGTCGTGGAGGAGGCAACCGGAAAACTCCTAGGGGCGCAGGTCCTGGCCGCAGAGGGGGGTGAAATCATCCAGGC
AGCGGCTCTAGCCCTGCGGGGTGGACTCCGTTACCAAGATCTAGCCGACCAGCTCTTCCCCTATCTCACGATGGTCGAGG
GCCTGAAGCTCTGTGCGCAAACCTTCACCAAAGACGTCAAGCAGCTGTCCTGCTGCGCGGGGTAA

Protein sequence : 
MTKNIALDILGMTCEHCAVTVQKALRNVPGVQDARVSFSQGQANIDLAVDVPTRDLIAAVNLVGYGAVAPGESGPKMGQI
PTGAQPRSSSDGMRIVIIGSGSAAFAAAIRAVEEGARVTMIEKGTLGGTCVNIGCVPSKILIRAAQMAHEQRAHPFEGLA
HATPAVDRTALVAQQQHRVEELRQEKYANVLTAYPAITFLQGTARFVDSHSVAVQSADGTEQTVQGDRFLIAVGARPHVP
GIPGIAQTPYWTSTEALVATELPQHLIVLGGSVVAVEMAQAFRRLGAQVTVLARSTLLSREDPALGEGLKAAFEAEGIRV
LLHTTPKSVRYERDTFLVETATETLRGDRLLVATGRTPNTDQLGLETIGVITADSGAIVVDDHMQTSVSHIFAAGDCTTL
PQFVYVAAAGGTRAAINMMGGDAVLDLQTMPAVVFTDPQVATVGLDARSAERLGIRAISRTLTLDNVPRALANFDTRGFI
TLVVEEATGKLLGAQVLAAEGGEIIQAAALALRGGLRYQDLADQLFPYLTMVEGLKLCAQTFTKDVKQLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 3e-134 61
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 4e-134 61
merA AFG30120.1 MerA Not tested PAGI-2 Protein 3e-134 61
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-131 60
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-132 59
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-132 59
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-132 59
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 1e-128 58
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 7e-129 58
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 4e-125 56
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 1e-78 41
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 2e-78 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Atc_1058 YP_004748407.1 mercuric reductase BAC0653 Protein 5e-134 59
Atc_1058 YP_004748407.1 mercuric reductase BAC0652 Protein 3e-128 57
Atc_1058 YP_004748407.1 mercuric reductase BAC0650 Protein 3e-125 54
Atc_1058 YP_004748407.1 mercuric reductase BAC0651 Protein 8e-79 41