Gene Information

Name : GYY_04440 (GYY_04440)
Accession : YP_004742506.1
Strain : Methanococcus maripaludis X1
Genome accession: NC_015847
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 820692 - 823790 bp
Length : 3099 bp
Strand : +
Note : COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

DNA sequence :
ATGTCTAATTTATGTGAAGATACGGTTGAACAGGGGACTCTTGAGCTTTTAAAGAGTATTGGATATGAAATAATTTCAGG
TCCTGAAATTGCGCCTGATGGAACTTCTCCTGAACGTAAAGATTATTCTGAAGTTGTGCTTGTTTCTCGGCTTAGGGATG
CAATTTCAAGAATAAATCCAAAAGTTCCAGTGGAAGCTCGAGAAGATGCACTTCGAAAAGTCTTGAGGCTTGAAAATCCA
AATTTACTCATGAATAACGAGAAGTTTCACGAGTTTATATTTAAGGGAATTGATGTAGAATACCCAATTGATGGAAGAGT
TAAGGGAGATAAGGTATATTTACTCGATAAAGACCCTTTGAAAAACGAATTTGTTGCAGTAAATCAATTTACAATCATTC
AGAATAATAAAAACAGGCGGCCAGATATTGTTATATTTGTAAACGGGCTTCCGCTTTCAGTTATTGAACTTAAAAATCCT
ACAAAAGAAGATGCTACGATATGGAGTGCTTATAATCAGATTCAAACGTATAAATCGGAAATTTCAGAACTTTTTAAGTA
TAACGAGCTCATACTAATTTCTGATGGTACGGAATCGCGAATAGGTACGCTTTCTTCAAATAAAGAGTGGTTTTTACCTT
GGAAATCAATTGATGGAACTTCTGAAATTAATAATGGGGTAAGCCAGCTTAAGATTTCAATTCTTGGAATGTTTGATAAA
ACGCGGTTTATTGACATAATAAAGAATTTTATTGTTTTTAAAAAAGATGGAAAAGACATTATAAAAGTTATTGCAGGATA
CCACCAGTATTTTGCAGCAAACCGTGCAATTGAAAAAACTATTGAAGCAGTTTCTGGAAATCGCCGGTGCGGTGTTGTAT
GGCACACGCAAGGGTCTGGGAAAAGTCTTACAATGGCTTTTTATGCTGGAAAACTTGCGATTACTCCTGAACTTAGAAAC
CCTACAATTGTAGTTGTAACTGACAGGAATGACCTTGACGACCAGCTCTTTGGAACGTTTGCGTCATGTATTGATGTATT
AAAACAGACTCCGGTTCAGGCAAAAAATGCAGAGGACTTAAAAGAACAGTTAAAGGTTGTATCGGGTGGAGTAATCTTTA
CAACGATGCAGAAGTTTTCTGTAGATGAACTTAATGCAAAATATCCGATGCTTTCTGATCGAGAAAACATAATCGTAATG
GCTGATGAAGCACACAGGAGCCAGTACGGTCTTAAAGCAAAATCAGTTGCGAGAAACGGTGAAGTTGGCATAACTTACGG
GTTTGCTAAATATTTACGTGATGCCCTACCAAATGCTTCATTTATTGGATTTACAGGAACTCCGATAGACTTTGAAGATA
AAAGCACCCGTTCGATATTTGGTGAATATATCGATATTTACGATGTAAGACGGGCTGTTGCTGATGGTAGAACTGTAAAA
ATCTACTATGAAAGCCGTGTTGCAAAAATCGGAATTGAAAACGACGTTCTTGCTAAACTTGACGCAGAATTTGAGGAAGT
TACAGAATTTGAAGAAAATTATAAAAAAGAGAAATTAAAGGGCAAATGGGCACAGCTTGAAGCGATTGTTGGAAGCAATG
ACAGGATTTCAAAAGTTGCACAGGATATTGTCAATCACTTTGAAAAGCGGGAAGAAACACTTACTGGAAAAGCAATTGTT
GTATGCATGAGCAGGAGAATTTGCGTTGATCTGTATGACGAAATTATTCGTTTAAGGCCTGAATGGCATAATGACGATGA
CAAGCTTGGTGTTTTAAAGGTTATAATGACAGGTTCTGCGGCTGACGGTACAGAATGGCAAAAACACATAAGGACAAAAG
GAAAACGAAAAGAGCTTGCTGAACACTTTAAAGATTCTGAAAGTGAATTTAAAATTGCGATTGTTCGTGATATGTGGCTT
ACTGGCTTTGATGTTCCGTGTTTGCACACACTTTATATCGATAAGCCTATGAAAGGGCACGGTTTAATGCAGGCGATTGC
AAGGGTAAACAGGGTATTTAGAGATAAGCCTGGAGGACTTGTTGTTGACTACATCGGAATTGCACAGGATTTAAAGTATG
CGCTTGTGAATTACACTTCAAATGGCGGTACTGGGAAACCAACGTATGATATAGAAGATGCAGTAAACCTCATGAAATCA
AAATACGAAGCTATGAAAGATTTCTTTTATGGCCATGACTACTCAAAATTCTTTAATGGAACAAATATTGAAAAAATGGA
TGTAATTCCAGAAACTTTAGAATTTATCCTTAATCAGCCTGATGGGAAAAAGCGGTTTGTTAAACTTGCGCTTGAACTTA
TAAAGTCATACGCTCTATCCCTGCCGCATGAAGAAGCCATAAAAATCCGTGAGGAAGTCGCGTTCTTTACAGGGGTTAAA
GCGGCACTTTATAAAAATACGGAAATTTCAGGAAAACCAGAAGATGAACTAAACAGCGCGATAAAACAGATTGTATCTGG
TGCAGTTCGTACTGATGGAATAATCGATGTATTTGGTGAAGCAGGACTTGAAAAACCCGATATTTCGATTCTGTCTGAAC
AATTCCTCGAAGATGTAAAAAACATGAAATATAAAAATTTAGCACTTGAAACGCTTAAAAAAATATTAAATGACGAAATA
AGGGCTAAATTTAAAAACAATCTTTTGCAGGAAAAGAAATTTTCAGAGATGATTGAAAACGCGATTAAAAGATACCACAA
TAAAGCGATAGATTCGGCGGCAGTTATTCAAGAACTCATAGCAATTGCAAAGGAAATTGAAAACGCTAAAAGAAGAGGGG
AAGAATTACATTTAACTGAAGAAGAGCTCGCATTTTACGATGCGTTATCAGACAACGATTCAGCAAAGGAAATTTTAGGA
ACAGAAGTTTTAAGTGAAATTGCAAGGGAACTGACTGACACTTTGAGGAAAAACATTTCCATTGACTGGGAAGTTAGGGA
AACTGTAAGGGCGACTTTAAGGGTCAGGGTTAAACGACTTCTTAAAAAATACGGGTATCCTCCAGACAAAGCACAGATTG
CAGCTGACCTTGTTTTAAAACAGGCTGAAACAATTTCTAAAGAATGGATGAATGCTTAA

Protein sequence :
MSNLCEDTVEQGTLELLKSIGYEIISGPEIAPDGTSPERKDYSEVVLVSRLRDAISRINPKVPVEAREDALRKVLRLENP
NLLMNNEKFHEFIFKGIDVEYPIDGRVKGDKVYLLDKDPLKNEFVAVNQFTIIQNNKNRRPDIVIFVNGLPLSVIELKNP
TKEDATIWSAYNQIQTYKSEISELFKYNELILISDGTESRIGTLSSNKEWFLPWKSIDGTSEINNGVSQLKISILGMFDK
TRFIDIIKNFIVFKKDGKDIIKVIAGYHQYFAANRAIEKTIEAVSGNRRCGVVWHTQGSGKSLTMAFYAGKLAITPELRN
PTIVVVTDRNDLDDQLFGTFASCIDVLKQTPVQAKNAEDLKEQLKVVSGGVIFTTMQKFSVDELNAKYPMLSDRENIIVM
ADEAHRSQYGLKAKSVARNGEVGITYGFAKYLRDALPNASFIGFTGTPIDFEDKSTRSIFGEYIDIYDVRRAVADGRTVK
IYYESRVAKIGIENDVLAKLDAEFEEVTEFEENYKKEKLKGKWAQLEAIVGSNDRISKVAQDIVNHFEKREETLTGKAIV
VCMSRRICVDLYDEIIRLRPEWHNDDDKLGVLKVIMTGSAADGTEWQKHIRTKGKRKELAEHFKDSESEFKIAIVRDMWL
TGFDVPCLHTLYIDKPMKGHGLMQAIARVNRVFRDKPGGLVVDYIGIAQDLKYALVNYTSNGGTGKPTYDIEDAVNLMKS
KYEAMKDFFYGHDYSKFFNGTNIEKMDVIPETLEFILNQPDGKKRFVKLALELIKSYALSLPHEEAIKIREEVAFFTGVK
AALYKNTEISGKPEDELNSAIKQIVSGAVRTDGIIDVFGEAGLEKPDISILSEQFLEDVKNMKYKNLALETLKKILNDEI
RAKFKNNLLQEKKFSEMIENAIKRYHNKAIDSAAVIQELIAIAKEIENAKRRGEELHLTEEELAFYDALSDNDSAKEILG
TEVLSEIARELTDTLRKNISIDWEVRETVRATLRVRVKRLLKKYGYPPDKAQIAADLVLKQAETISKEWMNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 48
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 48
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 47
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 47