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Name : dfrA (zobellia_877) Accession : YP_004735333.1 Strain : Zobellia galactanivorans DsiJT Genome accession: NC_015844 Putative virulence/resistance : Resistance Product : dihydrofolate reductase Function : - COG functional category : H : Coenzyme transport and metabolism COG ID : COG0262 EC number : 1.5.1.3 Position : 1049195 - 1049692 bp Length : 498 bp Strand : + Note : Dihydrofolate reductase catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, an essential step in de novo synthesis both of glycine and of purines and deoxythymidine phosphate (the precursors of DNA synthesis). It is also importan DNA sequence : ATGAACATCATAGCCTTGATAGCGGCAGCGGCCGACAACAATGCCCTAGGAAAGGACAACGACCTACTATGGCATTTACC GGATGATTTTAAGAGATTTAAAAGCCTTACTTCCGGGCACACCATTGTCATGGGCAGAAAAACATACGAGAGCTTTCCGA AACCCCTGCCCAATCGCAAGCACGTGATCATTACCCGCGACAAAAATTACACTGTAGACTACGATGTATGTGTTGTGGTA CATTCCTTAGAGGAAGCTTTGGAACTGGTAAAGGACGAAGACTTATCCTTTATAATCGGAGGCGGCGAAATCTACAAACT GGCCATGGAGCACGCCAATAAAATTGAACTCACCCGCGTACACGGCATTTTTGAAGATGCCGACACCTTCTTTCCGGAAA TACCCGAAAGCCAATGGGAACTTGCCAGCGAGCAATACCATCCCGCGGATGAAAAGCACAAATACGCCTTTACTTACCGC ACCTATTTAAAAATCTAA Protein sequence : MNIIALIAAAADNNALGKDNDLLWHLPDDFKRFKSLTSGHTIVMGRKTYESFPKPLPNRKHVIITRDKNYTVDYDVCVVV HSLEEALELVKDEDLSFIIGGGEIYKLAMEHANKIELTRVHGIFEDADTFFPEIPESQWELASEQYHPADEKHKYAFTYR TYLKI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| dfrA12 | ACF06156.1 | dihydrofolate reductase | Not tested | Tn5036-like | Protein | 1e-22 | 45 |
