Gene Information

Name : guaA (zobellia_568)
Accession : YP_004735030.1
Strain : Zobellia galactanivorans DsiJT
Genome accession: NC_015844
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 705858 - 707390 bp
Length : 1533 bp
Strand : -
Note : The GMP synthase is a glutamine amidotransferase from the de novo purine biosynthetic pathway. It catalyzes the synthesis of guanosine 5'monophosphate (GMP) from xanthosine 5'monophosphate (XMP), ATP and glutamine; Belongs to the Glutamine amidotransferas

DNA sequence :
ATGCAAAACAACGTCCTTATACTCGATTTCGGTTCTCAGTACACACAACTCATTGCTAGAAGGGTTAGAGAACTCAATAT
TTTCTGTGAAATAAAGCCTTATAACAAGCTTCCTGATGATTTATCGTCGTACAAAGCGGTAATCTTATCGGGGTCGCCCT
TTTCGGTACGTGCCGATGATGCGCCACATCCCGATTTGTCGCAAATCAGGGGCAAAAAGCCGCTATTGGCCGTTTGTTAC
GGGGCCCAATACCTTGCCCATTTCGGCGGGGGTAATGTTGCGCCTTCCAATACAAGGGAGTATGGTCGGGCAAATCTGTC
GTATATAAAACCTGATGAAGCTTTCTTTGAAGGGGTTTCGGAAGGGAGTCAAGTGTGGATGAGCCATAGTGATACCATTC
AGAAACTCCCGGAAAAAGGAGTGGTCTTGGCCAGTACGCACGATGTAGAACATGCTGCGTATAAGATTGAAGACGAGAGT
ACTTACGCCATACAGTTCCACCCAGAGGTTTATCATTCCAAAGATGGAAAGAAAATATTGGAAAACTTTTTGGTGAACAT
CGCCGGCCTTGAACAAACTTGGACCCCGGATGCATTTGTAGATATGACCGTTTCCGAGTTGAAACAAAAAATAGGAGACG
ACAAGGTAGTGCTTGGTTTGTCGGGTGGGGTTGATTCTACCGTGGCGGCAGTGCTTCTGCACAAGGCTATCGGAAAGAAC
CTGTATTGCATATTCGTAAATAACGGCCTGTTGAGAAAGAACGAATTTCAAGATGTTCTGGATCAATACGAACATATGGG
GTTGAACGTTAAAGGGGTTGATGCTTCGGCACGCTTTTTGGATGCCCTTGCAGGGGAAAGCGATCCTGAAAAGAAACGAA
AGATTATCGGAAAGGTGTTTATAGATGTGTTCGATGATGAGGCCCACTTGGTGAAAGATGTAAAATGGTTGGCGCAGGGT
ACCATATACCCTGATGTTATTGAATCGGTTTCGGCAACGGGAGGTCCGTCCGCAACCATCAAAAGCCACCACAATGTAGG
GGGCTTGCCTGATTTTATGAAACTCGAGGTGGTGGAGCCGCTAAAAATGTTGTTTAAGGATGAAGTCCGAAGGGTCGGTA
AGAGTATGGGTATCGATGATGAGCGTCTAGGGCGCCATCCCTTCCCAGGACCAGGATTGGCCATTCGTATACTAGGGGAT
ATAACCCGGGAGAAGGTGGCCATTTTGCAAGAAGTAGACCATATTTTTATCCAAGGATTACGCGATTGGGGACTTTATGA
CAAGGTTTGGCAGGCCGGAGCCATGCTTTTGCCCGTAAATAGTGTAGGCGTAATGGGAGATGAGCGTACTTATGAAAAAT
GCGTAGCTTTGCGGGCTGTAGAAAGTACCGATGGTATGACCGCCGACTGGGTGAATTTGCCATACGAGTTCTTGCAAAAG
ACGTCAAACGATATTATCAACAAAGTGCCGGGCGTGAACAGGGTCGTATATGACATAAGTTCAAAACCGCCCGCAACCAT
TGAATGGGAATAG

Protein sequence :
MQNNVLILDFGSQYTQLIARRVRELNIFCEIKPYNKLPDDLSSYKAVILSGSPFSVRADDAPHPDLSQIRGKKPLLAVCY
GAQYLAHFGGGNVAPSNTREYGRANLSYIKPDEAFFEGVSEGSQVWMSHSDTIQKLPEKGVVLASTHDVEHAAYKIEDES
TYAIQFHPEVYHSKDGKKILENFLVNIAGLEQTWTPDAFVDMTVSELKQKIGDDKVVLGLSGGVDSTVAAVLLHKAIGKN
LYCIFVNNGLLRKNEFQDVLDQYEHMGLNVKGVDASARFLDALAGESDPEKKRKIIGKVFIDVFDDEAHLVKDVKWLAQG
TIYPDVIESVSATGGPSATIKSHHNVGGLPDFMKLEVVEPLKMLFKDEVRRVGKSMGIDDERLGRHPFPGPGLAIRILGD
ITREKVAILQEVDHIFIQGLRDWGLYDKVWQAGAMLLPVNSVGVMGDERTYEKCVALRAVESTDGMTADWVNLPYEFLQK
TSNDIINKVPGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-107 48
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-107 48
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-107 48
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-106 46