Gene Information

Name : clpB1 (zobellia_4745)
Accession : YP_004739159.1
Strain : Zobellia galactanivorans DsiJT
Genome accession: NC_015844
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 5484469 - 5487069 bp
Length : 2601 bp
Strand : +
Note : ClpB is a homohexamer that is a part of a stress-induced multi-chaperone system involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds

DNA sequence :
ATGAACTTTAATAATTACACCACTAAATCACAGGAGGCCATTCAGCAAGCCCAGCAGATTGCACAGGGTTTGGGCCACCA
ACAAATTGAAAACGAACACTTGTTCAAGGCCATTTGGGAAGTCGATGAAAATGTACTCCCCTTCATTTTAAAGAAACTGA
ACATTAACATAGCCTTGCTGCAACAGATTTTAGCAAAGGAGCTAGAGAGTTTTCCAAAAGTTTCGGGAGGCGACCTTATG
TTGTCTCGCGAAGCAGGTAAAACCCTGAACGAAGCCAGTATCATTGCCAAGAAGATGGATGACGAATTCGTCTCCATTGA
ACACCTGTTATTGGCCATCTTAAAATCGAGCAGTAAAATTTCGCGTATATTAAAAGACCAAGGAGCCACCGAAAAAGACT
TAAAAGCGGCGATCGAGGAGTTGCGTAAAGGTGGAAAGGTAACCTCACAAAGTGCCGAAGACACCTACAATTCACTTGAT
AAATATGCCCGAAACCTTAACGAATTGGCCGATAGCGGTAAATTAGACCCGGTAATAGGACGTGACGAAGAGATTCGGCG
TATACTCCAAATCTTATCGAGAAGAACGAAGAACAACCCTATTTTGGTAGGCGAACCGGGTACCGGTAAAACTGCCATCG
CAGAAGGCTTGGCCCATAGGATCGTTCAAGGCGATGTTCCTGAAAATTTAAAGGACAAAATCATCTATTCCCTAGATATG
GGAGCCCTTATTGCAGGGGCCAAATACAAAGGTGAGTTTGAGGAACGTTTAAAATCGGTCATCAAAGAAGTAACTTCCTC
AGATGGCGATATCGTATTGTTCATTGACGAGATACACACCTTGGTAGGAGCCGGTGGCGGACAGGGGGCCATGGATGCCG
CCAACATTTTAAAACCGGCATTGGCCCGTGGGGAACTCCGAGCCATAGGAGCCACAACCCTTGACGAATACCAAAAATAT
TTCGAGAAAGACAAGGCCCTTGAAAGACGTTTTCAAAAAGTAGTGGTAAACGAGCCCGATACCGAGAGTGCCATTTCCAT
TCTTCGTGGTATTAAGGAAAAATACGAGGCCCACCATAAGGTCCGTATCAAAGATGAAGCGGTCATTGCCGCGGTCGAGC
TTTCGCAACGCTATATTACCAATCGCTTCCTTCCCGATAAAGCGATCGACCTCATGGACGAGGCCGCCTCTAAATTACGG
ATGGAAATCAACTCCAAACCGGAAGAACTAGATGTCCTTGACCGTAAGATCATGCAATTGGAGATTGAGATCGAAGCCAT
CAAAAGGGAAAACGACAAGGCAAAACTCAAATTGTTGAACGTTGATTTGGCGAATCTCAAGGAAGACCGAAACGAACTCT
TTGCCAAGTGGGAAAGTGAAAAATCGGTCGTTGATGAAATCCAAAAAACGAAACAAGACATAGAGGAATTCAAAAATGAG
GCCGAGCGCGCCGAGCGAAACGGGGATTACGGCAAAGTAGCCGAACTCAGGTACGGAAAAATCAAAGAAGCCCAAGAAAA
ACTGGAAGAACTCCAAAAAGCGCTCGATGAGCAACAACTGGGCGACACCATGATCAAAGAAGAGGTGACAAACGAAGACA
TCGCCGAAGTCGTGGCCAAATGGACCGGTATACCCGTTACCAAAATGCTACAGAGTGAACGCGAAAAACTCTTGAAACTG
GAAGATGTACTGCACAAAAGAGTAGTTGGCCAAGAAGAAGCCATTGTGGCCGTATCCGACGCCATAAGAAGAAGTCGCGC
CGGATTACAAGACGCCAACAAGCCTATCGGTTCGTTCTTGTTCCTTGGTACAACAGGGGTCGGTAAGACCGAGTTGGCCA
AAACCCTGGCTTCCTACCTTTTTGATGATGAAAGTGCCATGACCCGTATCGATATGAGCGAATATCAAGAACGTCACTCG
GTAAGTAGATTGGTGGGAGCACCTCCAGGATATGTTGGATACGATGAAGGGGGCCAGCTTACGGAAGCCGTTCGTAGAAG
ACCGTATTCCGTGGTATTACTCGACGAAATAGAAAAGGCCCATCCCGACACCTTCAATATTTTATTACAAGTGTTGGATG
AAGGAAGGCTTACGGACAACAAAGGTCGTGTTGCCGATTTCAAGAATACGATCATCATTATGACCAGTAATATGGGCAGC
AGTATTATTCAGGAAAAATACGAGAACAATAAAGACCCCTTCAGTGCAGCGGAAGCCGCGCGTGTGGAGGTACTAGGACT
CTTACGTAAAACCATACGCCCAGAGTTCCTTAACCGTATCGATGACATCATCATGTTTTCACCGCTTAGCCGCGAGGATA
TTTCCAAAATTGTTAGGCTACAGTTGAACAGTTTGAAGAAAACCATTGCGAAGCAACACATTACCATCGATGCTACGGAA
GAGGCTATCAATTACTTGGCCAATAAGGGCTACGACCCACAGTACGGGGCCCGTCCGATCAAAAGGGTAATACAGCGGGA
AGTGCTGAACAACCTTTCCAAAGAACTATTGAGCGGCACCATAAAAGCTGACAGTATCGTGCTTATCGATTCATTTAACG
ATGCACTGGTTTTTAGAAATCAAGACGAATTGGTGAAATAA

Protein sequence :
MNFNNYTTKSQEAIQQAQQIAQGLGHQQIENEHLFKAIWEVDENVLPFILKKLNINIALLQQILAKELESFPKVSGGDLM
LSREAGKTLNEASIIAKKMDDEFVSIEHLLLAILKSSSKISRILKDQGATEKDLKAAIEELRKGGKVTSQSAEDTYNSLD
KYARNLNELADSGKLDPVIGRDEEIRRILQILSRRTKNNPILVGEPGTGKTAIAEGLAHRIVQGDVPENLKDKIIYSLDM
GALIAGAKYKGEFEERLKSVIKEVTSSDGDIVLFIDEIHTLVGAGGGQGAMDAANILKPALARGELRAIGATTLDEYQKY
FEKDKALERRFQKVVVNEPDTESAISILRGIKEKYEAHHKVRIKDEAVIAAVELSQRYITNRFLPDKAIDLMDEAASKLR
MEINSKPEELDVLDRKIMQLEIEIEAIKRENDKAKLKLLNVDLANLKEDRNELFAKWESEKSVVDEIQKTKQDIEEFKNE
AERAERNGDYGKVAELRYGKIKEAQEKLEELQKALDEQQLGDTMIKEEVTNEDIAEVVAKWTGIPVTKMLQSEREKLLKL
EDVLHKRVVGQEEAIVAVSDAIRRSRAGLQDANKPIGSFLFLGTTGVGKTELAKTLASYLFDDESAMTRIDMSEYQERHS
VSRLVGAPPGYVGYDEGGQLTEAVRRRPYSVVLLDEIEKAHPDTFNILLQVLDEGRLTDNKGRVADFKNTIIIMTSNMGS
SIIQEKYENNKDPFSAAEAARVEVLGLLRKTIRPEFLNRIDDIIMFSPLSREDISKIVRLQLNSLKKTIAKQHITIDATE
EAINYLANKGYDPQYGARPIKRVIQREVLNNLSKELLSGTIKADSIVLIDSFNDALVFRNQDELVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 6e-99 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 5e-99 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB1 YP_004739159.1 chaperone ClpB VFG2076 Protein 4e-123 45